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anti-Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) Antibodies

The structure of the protein encoded by TRPA1 is highly related to both the protein ankyrin and transmembrane proteins. Additionally we are shipping TRPA1 Proteins (8) and TRPA1 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRPA1 8989 O75762
TRPA1 277328 Q8BLA8
TRPA1 312896 Q6RI86
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Top anti-TRPA1 Antibodies at antibodies-online.com

Showing 10 out of 93 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, WB WB Suggested Anti-TRPA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Stomach 100 μL Log in to see 2 to 3 Days
$289.00
Details
Guinea Pig Rabbit Un-conjugated ICC, IHC (fro), IF, IHC (p), IHC, WB Detection of TRPA1 in human brain membrane fraction using 2ug/ml of ABIN258315. Staining TRPA1 in mouse intestine using ABIN258315. 0.1 mL Log in to see 7 to 9 Days
$473.81
Details
Mouse Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: TRPA1 Antibody [ABIN4075369] - mouse brain lysate (reduced, denatured) using Rabbit antibody to 4th cytoplasmic loop of TRPA1 (ANKTM1): whole serum at 1:1000 dilution. Western Blot: TRPA1 Antibody [ABIN4075369] - Mouse brain lysate using Rabbit antibody to TRPA1 at 1 : 500 dilution incubated overnight at 4C. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Guinea Pig Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: TRPA1 Antibody [ABIN4093041] - IF on vagal nodose ganglia. Image from verified customer review. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Rat Rabbit Un-conjugated IHC, WB WB on mouse brain lysate (reduced, denatured) using Rabbit antibody to 4th cytoplasmic loop of TRPA1 (ANKTM1): whole serum (ABIN351100) at 1 : 1000 dilution. 100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Rabbit Un-conjugated IHC (p), WB TRPA1 antibody  ABIN1104836 (5 ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human skeletal muscle, followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 7 to 9 Days
$595.83
Details
Human Rabbit Un-conjugated IHC (p) Anti-TRPA1 antibody  ABIN1049431 IHC staining of human ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Guinea Pig Rabbit DyLight 650 ICC, IF, IHC (fro), IHC (p), WB   0.1 mL Log in to see 7 to 9 Days
$500.06
Details

TRPA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TRPA1 Antibodies

  1. Guinea Pig Polyclonal TRPA1 Primary Antibody for ICC, IHC (fro) - ABIN258315 : Yu, Gao, Peterson, Ouyang: TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus. in American journal of physiology. Gastrointestinal and liver physiology 2009 (PubMed)
    Show all 13 references for ABIN258315

  2. Rat (Rattus) Polyclonal TRPA1 Primary Antibody for IHC, WB - ABIN351100 : Jordt, Bautista, Chuang, McKemy, Zygmunt, Högestätt, Meng, Julius: Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. in Nature 2004 (PubMed)
    Show all 2 references for ABIN351100

  3. Human Polyclonal TRPA1 Primary Antibody for IF, IHC - ABIN2776190 : Chen, Zhang, Kort, Huth, Sun, Miesbauer, Cassar, Neelands, Scott, Moreland, Reilly, Hajduk, Kym, Hutchins, Faltynek: Molecular determinants of species-specific activation or blockade of TRPA1 channels. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 (PubMed)
    Show all 2 references for ABIN2776190

  4. Guinea Pig Polyclonal TRPA1 Primary Antibody for ICC, IF - ABIN409304 : Coavoy-Sánchez, Rodrigues, Teixeira, Soares, Torregrossa, Wood, Whiteman, Costa, Muscará: Hydrogen sulfide donors alleviate itch secondary to the activation of type-2 protease activated receptors (PAR-2) in mice. in Pharmacological research 2016 (PubMed)
    Show all 2 references for ABIN409304

  5. Mouse (Murine) Polyclonal TRPA1 Primary Antibody for IHC, IHC (p) - ABIN407536 : Zhang, Wickley, Sinha, Bratz, Damron: Propofol restores transient receptor potential vanilloid receptor subtype-1 sensitivity via activation of transient receptor potential ankyrin receptor subtype-1 in sensory neurons. in Anesthesiology 2011 (PubMed)

  6. Guinea Pig Polyclonal TRPA1 Primary Antibody for ICC, IF - ABIN4362896 : Hidaka, Ogawa, Kobayashi, Suzuki, Funayama, Nagashima, Fujimura, Aiba, Nakayama, Okuyama, Yamamoto: The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. in Nature immunology 2016 (PubMed)

More Antibodies against TRPA1 Interaction Partners

Zebrafish Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. Zebrafish TRPA1a is specialized for chemical sensing, whereas zTRPA1b responds to thermal stimuli.

  2. Inhibition of TRPA1 protein expression in zebrafish and mouse inner ears inhibits receptor cell function

  3. Larvae heterozygous for mutations in trpa1a respond to mustard oil to an extent similar to that of their wild-type siblings.

Fruit Fly (Drosophila melanogaster) Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. study concludes that the TRPA1 channel is not required for temperature synchronization but instead is required to repress activity during the warm part of the day

  2. Contribution of Drosophila TRPA1 to Metabolism.

  3. Citronellal can promote feeding deterrence of fruit flies through direct action on gustatory dTRPA1, revealing the first isoform-specific function for TRPA1(A).

  4. Recent work has uncovered the Transient Receptor Potential (TRP) channels TRPA1 mediating fly thermosensation.

  5. our results propose that the uracil/Duox (show DUOX1 Antibodies) pathway promotes bacteria expulsion from the gut (show GUSB Antibodies) through the HOCl-sensitive receptor, TRPA1(A)10b, thereby minimizing the chances that bacteria adapt to survive host defense systems.

  6. The mechanosensory channel, Piezo, has been identifieded in larval drosophila dorsal bipolar dendritic sensory neurons, with TRPA1 playing a subsidiary role.

  7. results suggest that specific isoforms of dTRPA1 can sense UV light via photochemical production of H2O2

  8. reported expression of TrpA1 in clock neurons is unlikely to be involved in generating the summer locomotor profile, suggesting that other TrpA1 neurons are responsible for the A component

  9. The activation of TRPA1-expressing neurons may differentially coordinate light/dark circadian entrainment, depending on the temperature.

  10. A 37-amino-acid-long intracellular region (encoded by a single exon) that is critical for dTRPA1 temperature responses.

Guinea Pig Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. TRPA1 activation suppresses gastric accommodation by increasing gastric tone through cholinergic neuronal pathways.

Caenorhabditis elegans (C. elegans) Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. Study reveals that TRPA-1, a cold-sensitive TRP channel, detects temperature drop in the environment to extend lifespan. This effect requires cold-induced, TRPA-1-mediated calcium influx and a calcium-sensitive PKC that signals to the transcription factor DAF-16/FOXO.

  2. harsh touch specifically required the DEG/ENaC proteins MEC-10 and DEGT-1 (F25D1.4), which represent putative components of a harsh touch mechanotransduction complex; responses to cold required the TRPA-1 channel and were MEC-10 and DEGT-1 independent

  3. This study demonstrates that trpa-1 encodes an ion channel that can be activated in response to mechanical pressure and is required for mechanosensory neuron function.

Human Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. data suggest that cardamonin is a selective TRPA1 antagonist, providing novel insight into the target of its anti-nociceptive activity.

  2. TRPA1 activation stimulates a cholinergic mechanism in a tetrodotoxin-resistant manner to cause muscle contraction.

  3. Taken together, these data demonstrated that TRPA1 activation played an important role in the enhanced production of reactive oxygen species induced by cold stress in A549 cell.

  4. Report activation of TRPA1 by o-chlorobenzylidene malononitrile as model of neuropathic pain.

  5. These findings suggest that the TRPA1-TRPV1 (show TRPV1 Antibodies) interaction may play an important role in regulating the function and excitability of pulmonary sensory neurons during airway inflammation

  6. TRPA1 was expressed in all studied regions (tongue, epiglottis, and pharynx), but was always localized below the basal lamina. No immunoreactivity for TRPA1 was found on epithelial cells.

  7. exposure to cigarette smoke extract initially causes an increase in the extracellular level of ROS (show ROS1 Antibodies), which in turn activates lung epithelial TRPA1

  8. Certain TRPA1 variants and tyrosine-to-phenylalanine mutants exhibited good function compared with non-mutated TRPA1 in transfected HEK293 cells

  9. the inflammatory cytokine TNF-a (show TNF Antibodies) can modulate the activity of the mechanosensitive ion channels TRPA1 and TRPV4 (show TRPV4 Antibodies) in odontoblasts via the p38 MAPK (show MAPK14 Antibodies) pathway but has differential effects on their expression.

  10. TRPA1 activity may modulate asthma, particularly among individuals living in locations prone to high levels of air pollution.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. Activation of enterocyte transient receptor potential cation channel subfamily A member 1(TRPA1) by food components has the potential to facilitate nutrient absorption

  2. contributes to cinnamaldehyde effects in LPS (show TLR4 Antibodies)-induced systemic inflammatory response syndrome

  3. Our study demonstrated the novel role of the TRPA1 channel in astrocytes under an amyloid beta-elicited inflammatory environment and thus its potential involvement in Alzheimer's disease pathogenesis

  4. Cold exposure caused mechanical hyperalgesia in an experimental arthritic model in a TRPA1-dependent manner.

  5. In TRPA1 knock-out mice hypersensitivity and impaired weight bearing in osteoarthritis limbs were significantly decreased.

  6. Trpa1 is involved in the ocular itch response in allergic conjunctivitis.

  7. TRPA1 was found to mediate acute inflammation and the development of degenerative cartilage changes and joint pain in MIA (show MIA Antibodies)-induced experimental OA in the mouse.

  8. exposure to cigarette smoke extract initially causes an increase in the extracellular level of ROS (show ROS1 Antibodies), which in turn activates lung epithelial TRPA1

  9. K14Cre-Trpa1fl/fl mice had a big mechanosensitivity deficit at the behavioral and primary afferent levels, and decreased mechanically-evoked ATP release. This is not due to low Trpa1 because these cells even in controls have little if any Trpa1.

  10. Data suggest that blockage of transient receptor potential (TRP) channels TRPA1, TRPV4 (show TRPV4 Antibodies) and possibly TRPM8 (show TRPM8 Antibodies) may represent a therapeutic option for patients with colonic discomfort and pain.

TRPA1 Antigen Profile

Protein Summary

The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined\; however, studies indicate the function may involve a role in signal transduction and growth control.

Gene names and symbols associated with TRPA1

  • transient receptor potential cation channel, subfamily A, member 1a (trpa1a) antibody
  • Transient receptor potential A1 (TrpA1) antibody
  • transient receptor potential cation channel, subfamily A, member 1 (TRPA1) antibody
  • transient receptor potential A1 (TcasGA2_TC002449) antibody
  • tryptophan synthase subunit alpha 1 (trpA1) antibody
  • transient receptor potential cation channel, subfamily A, member 1 (trpa1) antibody
  • transient receptor potential cation channel, subfamily A, member 1 (Trpa1) antibody
  • Protein TRPA-1 (trpa-1) antibody
  • Anktm1 antibody
  • CG5751 antibody
  • CG5761 antibody
  • CT18073 antibody
  • dANKTM1 antibody
  • Dmel\\CG5751 antibody
  • DmTRPA1 antibody
  • dTrpA antibody
  • dtrpA1 antibody
  • FEPS antibody
  • GLEAN_02449 antibody
  • TrpA antibody
  • trpA1 antibody

Protein level used designations for TRPA1

transient receptor potential cation channel subfamily A member 1 , CG5751-PG , CG5751-PH , CG5751-PI , CG5751-PJ , CG5751-PK , TrpA1-PG , TrpA1-PH , TrpA1-PI , TrpA1-PJ , TrpA1-PK , transient receptor potential A1 , transient receptor potential cation channel , transient-receptor-potential A1 , ankyrin-like protein 1 , transient receptor potential cation channel, subfamily A, member 1 , tryptophan synthase subunit alpha 1 , transient receptor potential cation channel subfamily A member 1-like , ankyrin-like with transmembrane domains 1 , ankyrin-like with transmembrane domains protein 1 , transformation-sensitive protein p120 , ANKTM1

GENE ID SPECIES
474351 Danio rerio
39015 Drosophila melanogaster
420180 Gallus gallus
464230 Pan troglodytes
486994 Canis lupus familiaris
505317 Bos taurus
658860 Tribolium castaneum
694623 Macaca mulatta
9895859 Achromobacter xylosoxidans A8
100152934 Sus scrofa
100158526 Xenopus (Silurana) tropicalis
100414472 Callithrix jacchus
100460642 Pongo abelii
100526649 Cavia porcellus
178118 Caenorhabditis elegans
8989 Homo sapiens
277328 Mus musculus
312896 Rattus norvegicus
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