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Transient Receptor Potential Cation Channel, Subfamily C, Member 1 Proteins (TRPC1)

TRPC1 encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Additionally we are shipping Transient Receptor Potential Cation Channel, Subfamily C, Member 1 Antibodies (66) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRPC1 7220 P48995
TRPC1 22063 Q61056
Rat TRPC1 TRPC1 89821 Q9QX01
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Top Transient Receptor Potential Cation Channel, Subfamily C, Member 1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

TRPC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) Interaction Partners

Xenopus laevis Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) interaction partners

  1. Endogenous as well as overexpressed xTRPV6 interacts with xTRPC1.

  2. our results suggest that calcium influx through mechanosensitive TRPC1 channels on filopodia activates calpain to control growth cone turning during development.

  3. This study suggested that BDNF (show BDNF Proteins)-induced synaptic potentiation involves coordinated presynaptic and postsynaptic responses and identifies TRPC1 as a molecular mediator for postsynaptic Ca2 (show CA2 Proteins)+ elevation required for BDNF (show BDNF Proteins)-induced synaptic plasticity.

  4. XTRPC1, a Xenopus homolog of mammalian TRPC1, is required for proper growth cone turning responses of Xenopus spinal neurons to netrin-1 (show NTN1 Proteins), brain-derived neurotrophic factor (show BDNF Proteins) and myelin-associated glycoprotein (show MAG Proteins), but not to semaphorin 3A (show SEMA3A Proteins).

  5. downregulation of Xenopus TRP-1 (show TYRP1 Proteins) (xTRPC1) expression with a specific morpholino oligonucleotide abolished the growth-cone turning and Ca2 (show CA2 Proteins)+ elevation induced by a netrin-1 (show NTN1 Proteins) gradient

Zebrafish Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) interaction partners

  1. These results provide the first in vivo evidence that TRPC1 is essential for angiogenesis in zebrafish.

Rabbit Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) interaction partners

  1. a novel activation mechanism for TRPC1 SOCs in VSMCs, in which store depletion induces formation of TRPC1-Galphaq-PLCbeta1 complexes that lead to PKC stimulation and channel gating.

Human Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) interaction partners

  1. OC. Our results provide the basis for further investigations of the drug-resistance-related functions of TRPC1 in ovarian cancer and other forms of cancer.

  2. TRPC1 mRNA and protein levels were increased in FCDIa, FCDIIa, and FCDIIb patients.

  3. HIF-1alpha (show HIF1A Proteins) knockdown attenuated hypoxia-induced BMP4 (show BMP4 Proteins) expression and knockdown of either HIF-1alpha (show HIF1A Proteins) or BMP4 (show BMP4 Proteins) abolished hypoxia-induced TRPC expression and basal [Ca(2 (show CA2 Proteins)+)]i.

  4. Single nucleotide polymorphisms in TYRP1 (show TYRP1 Proteins) gene is associated with multiple primary melanoma.

  5. In c-kit+ cardiac progenitor cells, silencing TRPC1 significantly reduced the Ca2 (show CA2 Proteins)+ signaling through store-operated Ca2 (show CA2 Proteins)+ channels, decreased cell proliferation and migration, and reduced expression of cyclin D1 (show CCND1 Proteins), cyclin E (show CCNE1 Proteins), and/or p-Akt (show AKT1 Proteins).

  6. RhoA (show RHOA Proteins) interacts with and activates TRPC1 and thus stimulates rapid epithelial restitution after injury by inducing Ca(2 (show CA2 Proteins)+) signaling.

  7. TRPC1 may take part both in regulation of store-operated Ca(2 (show CA2 Proteins)+) entry and proliferation of hepatocellular carcinoma cells.

  8. The decrease in mitochondrial Ca(2 (show CA2 Proteins)+) loading following CPA (show CPA1 Proteins)-induced endoplasmic reticulum depletion in TRPC1-silenced Huh7 cells suggests a possible role of TRPC1 in hepatocellular carcinoma cell apoptosis.

  9. data demonstrate that trafficking via fast recycling endosomes determines TRPC1-STIM1 (show STIM1 Proteins) clustering within ER-PM junctions following ER-Ca2 (show CA2 Proteins)+ store depletion which is critical for the surface expression and function of the channel.

  10. Mutation in TYRP1 (show TYRP1 Proteins) is associated with oculocutaneous albinism.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) interaction partners

  1. The results of this study showed that Loss of TRPC1 facilitated the gliotic response induced by increased intraocular pressure (IOP), suggesting that the channel might contribute to the glial mechanosusceptibility.

  2. transient receptor potential channel 1 suppression of basal sphingosine kinase 1 (show SPHK1 Proteins) activity enables endothelial cell-barrier destabilization by edemagenic agonists

  3. Together the data suggests that Ca(2 (show CA2 Proteins)+) entry via the TRPC1 channels is essential for the activation of CaCC (show CLCA1 Proteins)

  4. TRPC1(-/-) mice exhibited decreased survival, severe lung injury, and systemic bacterial dissemination upon infection.

  5. TRPC1 controls the activity of further Ca(2 (show CA2 Proteins)) influx channels and thus regulates the maintenance of intracellular Ca(2 (show CA2 Proteins)) gradients which are critical for cell migration.

  6. Soleus muscle TRPC1 mRNA was unaltered during the hindlimb unloading-reloading period. However, protein expression remained depressed through the reloading process. Decreased localization of TRPC1 to the sarcolemma was observed.

  7. These results suggest that the AR region of TRPC3 (show TRPC3 Proteins) could mediate the heteromeric TRPC3 (show TRPC3 Proteins)/1 formation, and the heteromeric TRPC3 (show TRPC3 Proteins)/1 could participate in regulating the resting cytosolic Ca(2 (show CA2 Proteins)+) levels in skeletal muscle.

  8. TRPC1 participates in the pathophysiological development of hypoxic pulmonary hypertension in the mouse model.

  9. Data suggest that TRPC1 and TRPC4 (show TRPC4 Proteins) are involved in the sprouting of sensory neurons following bladder cystitis, which leads to overactive bladder disease.

  10. Results indicate an important role of TRPC1 in pulmonary vascular remodeling underlying the development of hypoxia-induced pulmonary hypertension.

Cow (Bovine) Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) interaction partners

  1. the link between HG-induced changes in TRPC1 expression, enhanced Ca(2 (show CA2 Proteins)+) entry, and endothelial dysfunction require further study

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) interaction partners

  1. Demonstrate a novel role of the NO-cGMP-PKG (show PRKG1 Proteins) pathway in the inhibition of 11,12-EET-induced smooth muscle hyperpolarization and relaxation via PKG (show PRKG1 Proteins)-mediated phosphorylation of TRPC1.

  2. Data found that the pig adrenal medulla expressed predominantly TRPC1, TRPC5 (show TRPC5 Proteins), and TRPC6 (show TRPC6 Proteins) transcripts. The expression level of these TRPCs was significantly elevated in the adrenal medulla from pigs with metabolic syndrome.

Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) Protein Profile

Protein Summary

This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.

Gene names and symbols associated with TRPC1

  • transient receptor potential cation channel, subfamily C, member 1 (trpc1)
  • transient receptor potential cation channel, subfamily C, member 1 (LOC100219592)
  • transient receptor potential cation channel, subfamily C, member 1 (TRPC1)
  • calcium influx channel TRPC1A-like (TRPC1A)
  • transient receptor potential cation channel, subfamily C, member 1 (Trpc1)
  • tyrosinase-related protein 1 (TYRP1)
  • b-PROTEIN protein
  • CAS2 protein
  • CATB protein
  • GP75 protein
  • HTRP-1 protein
  • Mtrp1 protein
  • OCA3 protein
  • TRP protein
  • Trp1 protein
  • Trpc1 protein
  • Trrp1 protein
  • TYRP protein
  • xtrpc1 protein

Protein level used designations for TRPC1

transient receptor potential protein , short transient receptor potential channel 1 , transient receptor potential cation channel, subfamily C, member 1 , transient receptor potential cation channel subfamily C member 1 , short transient receptor potential channel 1-like , calcium influx channel TRPC1A , putative calcium influx channel TRPC1A , TRP-1 , transient receptor potential canonical 1 , transient receptor protein 1 , trp-related protein 1 , transient receptor potential channel 1 , store-operated calcium channel , transient receptor potential channel subfamily C member 1 , 5,6-dihydroxyindole-2-carboxylic acid oxidase , DHICA oxidase , catalase B , glycoprotein 75 , melanoma antigen gp75

GENE ID SPECIES
399136 Xenopus laevis
570841 Danio rerio
100219592 Taeniopygia guttata
100462673 Oncorhynchus mykiss
100465650 Ailuropoda melanoleuca
100556438 Anolis carolinensis
100009352 Oryctolagus cuniculus
7220 Homo sapiens
22063 Mus musculus
89821 Rattus norvegicus
282100 Bos taurus
424776 Gallus gallus
485698 Canis lupus familiaris
100156938 Sus scrofa
7306 Homo sapiens
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