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Transient Receptor Potential Cation Channel, Subfamily C, Member 6 Proteins (TRPC6)

The protein encoded by TRPC6 forms a receptor-activated calcium channel in the cell membrane. Additionally we are shipping Transient Receptor Potential Cation Channel, Subfamily C, Member 6 Antibodies (130) and Transient Receptor Potential Cation Channel, Subfamily C, Member 6 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRPC6 7225 Q9Y210
TRPC6 22068 Q61143
Rat TRPC6 TRPC6 89823  
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Top Transient Receptor Potential Cation Channel, Subfamily C, Member 6 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

TRPC6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
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More Proteins for Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) Interaction Partners

Cow (Bovine) Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) interaction partners

  1. These findings suggest that lysoPC induces CaM (show KRIT1 Proteins) phosphorylation at Tyr (show TYR Proteins)(99) by a Src (show SRC Proteins) family kinase and that phosphorylated CaM (show KRIT1 Proteins) activates PI3K to produce PIP3, which promotes TRPC6 translocation to the cell membrane.

  2. analysis of a TRPC6-TRPC5 (show TRPC5 Proteins) channel cascade that restricts endothelial cell movement

Human Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) interaction partners

  1. Genetic Interactions Between TRPC6 and NPHS1 (show NPHS1 Proteins) Variants Affect Posttransplant Risk of Recurrent Focal Segmental Glomerulosclerosis.

  2. These findings suggest that lysoPC induces CaM (show CALM1 Proteins) phosphorylation at Tyr (show TYR Proteins)(99) by a Src (show SRC Proteins) family kinase and that phosphorylated CaM (show CALM1 Proteins) activates PI3K (show PIK3CA Proteins) to produce PIP3, which promotes TRPC6 translocation to the cell membrane.

  3. This study demonstrated that TRPC6 reduction or haploinsufficiency leads to altered neuronal development, morphology and function.

  4. TRPC6 specifically interacts with APP (show APP Proteins) leading to inhibition of its cleavage by gamma-secretase and reduction in Abeta (show APP Proteins) production.

  5. results suggest that TRPC6 regulates metabolism to affect HIF-1alpha (show HIF1A Proteins) stability and consequent glucose metabolism in human glioma cells under hypoxia

  6. HIF-1alpha (show HIF1A Proteins) knockdown attenuated hypoxia-induced BMP4 (show BMP4 Proteins) expression and knockdown of either HIF-1alpha (show HIF1A Proteins) or BMP4 (show BMP4 Proteins) abolished hypoxia-induced TRPC expression and basal [Ca(2 (show CA2 Proteins)+)]i.

  7. TRPC3 (show TRPC3 Proteins) and TRPC6 participate diversely in synaptic reorganization in the mossy fiber pathway in temporal lobe epilepsy.

  8. the transient receptor potential canonical-6 (TRPC6) calcium-permeable channel in the alveolar macrophages also functions to shunt the transmembrane potential generated by proton pumping.

  9. TRPC6 genetic variants are promising candidate predictors of nervous system involvement in systemic lupus erythematosus

  10. Selectively activating endothelial TRPC6 rescues transendothelial migration

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) interaction partners

  1. AngII-injured podocyte had a significant increase in apoptosis, while silencing TRPC6 could decrease the apoptosis induced by AngII.

  2. TRPC3 (show TRPC3 Proteins) and TRPC6 participate diversely in synaptic reorganization in the mossy fiber pathway in temporal lobe epilepsy.

  3. the transient receptor potential canonical-6 (TRPC6) calcium-permeable channel in the alveolar macrophages also functions to shunt the transmembrane potential generated by proton pumping.

  4. Selectively activating endothelial TRPC6 rescues transendothelial migration

  5. MicroRNA-26a prevents endothelial cell apoptosis by directly targeting TRPC6 in the setting of atherosclerosis.

  6. These findings indicate that the mTORC2 (show CRTC2 Proteins) signaling pathway regulates TRPC6 in podocytes but that the mTORC1 signaling pathway does not appear to exert an effect on TRPC6.

  7. these findings provide strong evidence for a role of immunophilins, including FKBP25 (show FKBP3 Proteins) and FKBP38 (show FKBP8 Proteins), in NCCE mediated by TRPC6.

  8. Locally generated Sdc4 (show SDC4 Proteins) may play a role in regulating TRPC6 channels, and may contribute to glomerular pathology.

  9. Results suggest that stretch-accelerated wound closure is due to the ATP release through mechanosensitive hemichannels from the foremost cells and the subsequent Ca(2 (show CA2 Proteins)+) waves mediated by P2Y (show P2RY1 Proteins) and TRPC6 activation.

  10. Results suggest that IL-17A (show IL17A Proteins) may promote brain ischemia reperfusion injury through the increase of calpain-mediated TRPC6 proteolysis

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) interaction partners

  1. Data found that the pig adrenal medulla expressed predominantly TRPC1 (show TRPC1 Proteins), TRPC5 (show TRPC5 Proteins), and TRPC6 transcripts. The expression level of these TRPCs was significantly elevated in the adrenal medulla from pigs with metabolic syndrome.

Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) Protein Profile

Protein Summary

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

Gene names and symbols associated with TRPC6

  • transient receptor potential cation channel, subfamily C, member 6 (TRPC6)
  • transient receptor potential cation channel, subfamily C, member 6 (trpc6)
  • transient receptor potential cation channel, subfamily C, member 6 (Trpc6)
  • transient receptor potential cation channel, subfamily C, member 6a (trpc6a)
  • AV025995 protein
  • bZ1P14.9 protein
  • FSGS2 protein
  • LLHWJM002 protein
  • LLHWJM003 protein
  • LLHWJM004 protein
  • mtrp6 protein
  • si:rp71-1p14.9 protein
  • TRP-6 protein
  • trp6 protein
  • trpc6 protein
  • Trrp6 protein

Protein level used designations for TRPC6

transient receptor potential cation channel, subfamily C, member 6 , short transient receptor potential channel 6-like , TRP-6 , short transient receptor potential channel 6 , transient receptor protein 6 , calcium entry channel , transient receptor potential channel subfamily C member 6

GENE ID SPECIES
100061175 Equus caballus
414293 Bos taurus
418989 Gallus gallus
100079408 Ornithorhynchus anatinus
100395510 Callithrix jacchus
100479387 Ailuropoda melanoleuca
100545253 Meleagris gallopavo
100554810 Anolis carolinensis
7225 Homo sapiens
22068 Mus musculus
89823 Rattus norvegicus
100347206 Oryctolagus cuniculus
489435 Canis lupus familiaris
100271728 Sus scrofa
407151 Bos taurus
100135637 Cavia porcellus
451503 Pan troglodytes
563989 Danio rerio
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