anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) Antibodies

The protein encoded by TRPC6 forms a receptor-activated calcium channel in the cell membrane. Additionally we are shipping Transient Receptor Potential Cation Channel, Subfamily C, Member 6 Proteins (8) and Transient Receptor Potential Cation Channel, Subfamily C, Member 6 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRPC6 7225 Q9Y210
TRPC6 22068 Q61143
TRPC6 89823  
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Top anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 Antibodies at antibodies-online.com

Showing 10 out of 131 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-TRPC6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Horse Rabbit Un-conjugated WB WB Suggested Anti-TRPC6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Horse Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-TRPC6 Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB ABIN334518 (0.03 ug/ml) staining of Human Placenta lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$368.50
Details
Human Goat Un-conjugated IP, ELISA, WB Western Blot: TRPC6 Antibody [NBP1-00142] - Analysis of TRPC6 in human placenta lysate (35ug protein in RIPA buffer) using this antibody at 0.03 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$447.56
Details
Chimpanzee Mouse Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 10 to 12 Days
$411.18
Details
Mouse Rabbit Un-conjugated WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-TRPC6 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti-TRPC6 antibody, Western blotting Lane 1: Rat Lung Tissue Lysate Lane 2: 293T Cell Lysate Lane 3: 293T Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Mouse Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$326.89
Details

TRPC6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 Antibodies

  1. Human Polyclonal TRPC6 Primary Antibody for IP, ELISA - ABIN314245 : Foller, Kasinathan, Koka, Lang, Shumilina, Birnbaumer, Lang, Huber: TRPC6 contributes to the Ca(2+) leak of human erythrocytes. in Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008 (PubMed)
    Show all 4 Pubmed References

  2. Mouse (Murine) Polyclonal TRPC6 Primary Antibody for FACS, ELISA - ABIN269792 : Winn, Conlon, Lynn, Farrington, Creazzo, Hawkins, Daskalakis, Kwan, Ebersviller, Burchette, Pericak-Vance, Howell, Vance, Rosenberg: A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. in Science (New York, N.Y.) 2005 (PubMed)

More Antibodies against Transient Receptor Potential Cation Channel, Subfamily C, Member 6 Interaction Partners

Cow (Bovine) Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) interaction partners

  1. These findings suggest that lysoPC induces CaM (show KRIT1 Antibodies) phosphorylation at Tyr (show TYR Antibodies)(99) by a Src (show SRC Antibodies) family kinase and that phosphorylated CaM (show KRIT1 Antibodies) activates PI3K to produce PIP3, which promotes TRPC6 translocation to the cell membrane.

  2. analysis of a TRPC6-TRPC5 (show TRPC5 Antibodies) channel cascade that restricts endothelial cell movement

Human Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) interaction partners

  1. potential implications of transient receptor potential (TRP) channels in the pathogenesis of intestinal fibrosis, since they are known to act as cellular stress sensors/transducers affecting intracellular Ca(2 (show CA2 Antibodies)+) homeostasis/dynamics, and are involved in a broad spectrum of cell pathophysiology including inflammation and tissue remodeling.

  2. Studies provide evidence that the TRPC6-mediated signaling pathway in kidney cells is under control of reactive oxygen species under both physiological and pathological conditions. [review]

  3. SARAF (show TMEM66 Antibodies) modulates TRPC1 (show TRPC1 Antibodies), but not TRPC6, channel function in a STIM1 (show STIM1 Antibodies)-independent manner

  4. Functional interaction of upregulated CaSR (show CASR Antibodies) and upregulated TRPC6 in pulmonary artery smooth muscle cells from idiopathic pulmonary arterial hypertension patients may play an important role in the development and progression of sustained pulmonary vasoconstriction and pulmonary vascular remodeling.

  5. Our comprehensive analysis of human disease-causing TRPC6 mutations reveals loss of TRPC6 function as an additional concept of hereditary focal segmental glomerulosclerosis and provides molecular insights into the mechanism responsible for the loss-of-function phenotype of TRPC6 G757D in humans

  6. study demonstrated that the various mechanisms regulating MDR in HCC (show FAM126A Antibodies) cells are calcium dependent through the TRPC6/calcium/STAT3 (show STAT3 Antibodies) pathway. We propose that targeting TRPC6 in HCC (show FAM126A Antibodies) may be a novel antineoplastic strategy, especially combined with chemotherapy

  7. n response to stretching (20%), ATP was released only from the foremost cells at the wound edge; it then diffused to the cells behind the wound edge and activated the P2Y (show P2RY1 Antibodies) receptors, which caused propagating Ca(2 (show CA2 Antibodies)+) waves via TRPC6

  8. Data suggest that targeted manipulation of protein kinase C (show PKC Antibodies) isoforms PKCalpha (show PKCa Antibodies), PKCbeta, and PKCeta might be beneficial in certain proteinuric kidney diseases with altered transient receptor potential cation channel subfamily C member 6 protein (TRPC6) functions.

  9. Insulin increases the expression of TRPC6 channels in podocytes by activation of the calcineurin-dependent pathway.

  10. This study described the expression and functional relevance of TRPC6 in the pathophysiology of HK-2 (show HK2 Antibodies) cell following ischemia reperfusion.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) interaction partners

  1. Administration of soluble klotho (show KL Antibodies) significantly reduced obstruction-induced renal fibrosis in wild-type mice, but not in Trpc6 knockout mice, indicating that klotho (show KL Antibodies) and TRPC6 inhibition act in the same pathway to protect against obstruction-induced renal fibrosis.

  2. In the present study, we have explored the hypothesis that TRPC3 (show TRPC3 Antibodies) and TRPC6 channels expressed in VSMCs may have a differential contribution to the regulation of vascular tone, which could be relevant for the changes in vascular reactivity associated with essential hypertension

  3. This study demonstrated that Transient Receptor Potential Canonical 6 (TRPC6) and Orai2 (show ORAI2 Antibodies) form stromal interaction molecule 2 (STIM2 (show Stim2 Antibodies))-regulated neuronal-store-operated Ca(2 (show CA2 Antibodies)+) influx (nSOC) channel complex in hippocampal synapse and the resulting Ca(2 (show CA2 Antibodies)+) influx is critical for long-term maintenance of mushroom spines in hippocampal neurons.

  4. ASIV may prevent HG-induced podocyte apoptosis via downregulation of TRPC6, which is possibly mediated via the calcineurin/NFAT (show NFATC1 Antibodies) signaling pathway.

  5. the mTORC2 (show CRTC2 Antibodies)/Akt (show AKT1 Antibodies)/NFkappaB pathway-mediated activation of TRPC6 participates in adriamycin-induced podocyte apoptosis.

  6. AngII-injured podocyte had a significant increase in apoptosis, while silencing TRPC6 could decrease the apoptosis induced by AngII.

  7. TRPC3 (show TRPC3 Antibodies) and TRPC6 participate diversely in synaptic reorganization in the mossy fiber pathway in temporal lobe epilepsy.

  8. the transient receptor potential canonical-6 (TRPC6) calcium-permeable channel in the alveolar macrophages also functions to shunt the transmembrane potential generated by proton pumping.

  9. Selectively activating endothelial TRPC6 rescues transendothelial migration

  10. MicroRNA-26a prevents endothelial cell apoptosis by directly targeting TRPC6 in the setting of atherosclerosis.

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) interaction partners

  1. Data found that the pig adrenal medulla expressed predominantly TRPC1 (show TRPC1 Antibodies), TRPC5 (show TRPC5 Antibodies), and TRPC6 transcripts. The expression level of these TRPCs was significantly elevated in the adrenal medulla from pigs with metabolic syndrome.

Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) Antigen Profile

Protein Summary

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

Gene names and symbols associated with TRPC6

  • transient receptor potential cation channel subfamily C member 6 (TRPC6) antibody
  • transient receptor potential cation channel, subfamily C, member 6 (Trpc6) antibody
  • transient receptor potential cation channel, subfamily C, member 6a (trpc6a) antibody
  • transient receptor potential cation channel subfamily C member 6 (Trpc6) antibody
  • transient receptor potential cation channel subfamily C member 6 (trpc6) antibody
  • AV025995 antibody
  • bZ1P14.9 antibody
  • FSGS2 antibody
  • LLHWJM002 antibody
  • LLHWJM003 antibody
  • LLHWJM004 antibody
  • mtrp6 antibody
  • si:rp71-1p14.9 antibody
  • TRP-6 antibody
  • trp6 antibody
  • trpc6 antibody
  • Trrp6 antibody

Protein level used designations for TRPC6

TRP-6 , short transient receptor potential channel 6 , transient receptor protein 6 , calcium entry channel , transient receptor potential cation channel, subfamily C, member 6 , transient receptor potential channel subfamily C member 6 , short transient receptor potential channel 6-like

GENE ID SPECIES
7225 Homo sapiens
22068 Mus musculus
89823 Rattus norvegicus
407151 Bos taurus
418989 Gallus gallus
451503 Pan troglodytes
489435 Canis lupus familiaris
563989 Danio rerio
100061175 Equus caballus
100079408 Ornithorhynchus anatinus
100135637 Cavia porcellus
100271728 Sus scrofa
100347206 Oryctolagus cuniculus
100395510 Callithrix jacchus
100479387 Ailuropoda melanoleuca
100545253 Meleagris gallopavo
100554810 Anolis carolinensis
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