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TRPM5 encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. Additionally we are shipping TRPM5 Proteins (6) and many more products for this protein.
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Rat (Rattus) Polyclonal TRPM5 Primary Antibody for IHC, WB - ABIN446170
Delgiorno, Hall, Takeuchi, Pan, Halbrook, Washington, Olive, Spence, Sipos, Wright, Wells, Crawford: Identification and manipulation of biliary metaplasia in pancreatic tumors. in Gastroenterology 2013
Our results suggest roles of TRPM3 (show TRPM3 Antibodies) and TRPM5 gene variants in the susceptibility to or clinical expression of Systemic sclerosis
The PKC (show PRRT2 Antibodies)-dependent effect of GLP-1 (show GCG Antibodies) on membrane potential and electrical activity was mediated by activation of Na(+)-permeable TRPM4 (show TRPM4 Antibodies) and TRPM5 channels by mobilization of intracellular Ca(2 (show CA2 Antibodies)+) from thapsigargin-sensitive Ca(2 (show CA2 Antibodies)+) stores
In a Turkish population, genetic polymorphism in TRPM5 genes modify individual susceptibility to metabolic syndrome.
TRPM5-mediated Na(+) entry to promote Ca(2+) uptake via an NCX to trigger MUC5AC secretion
TrpM5 expression was similar throughout the olfactory glomeruli.
The TRPM5 gene rs34551253 (Ala456Thr) polymorphism may be associated with increased risk of developing primary open angle glaucoma in the Turkish population.
AZIN1 (show AZIN1 Antibodies) rs2679757 and TRPM5 rs886277 are associated with the risk of HBV-related liver cirrhosis in Chinese.
extracellular Zn(2+) inhibits TRPM5 channels, and the residues in the outer pore loop of TRPM5 are critically involved in the inhibition.
common TRPM5 variants are likely to be associated with prediabetic phenotypes; and this may in turn contribute to the development of type 2 diabetes mellitus
results suggest TRPM5 may play a role in upregulating endogenous expression of TRPA1 (show TRPA1 Antibodies), that TRPA1 (show TRPA1 Antibodies) activation may be an additional trigger for co-expressed calcium-dependent ion channels such as TRPM5, and that TRPM5 may amplify responses to TRPA1 (show TRPA1 Antibodies) ligands
This study demonstrate that Trpm5 is transiently expressed in a subpopulation of mature OSNs in the embryonic olfactory epithelium, indicating that Trpm5 channels could play a specific role in utero during a narrow developmental time window.
The PKC (show PKC Antibodies)-dependent effect of GLP-1 (show GCG Antibodies) on membrane potential and electrical activity was mediated by activation of Na(+)-permeable TRPM4 (show TRPM4 Antibodies) and TRPM5 channels by mobilization of intracellular Ca(2 (show CA2 Antibodies)+) from thapsigargin-sensitive Ca(2 (show CA2 Antibodies)+) stores
The present findings confirm and extend our recent findings that Trpm5 KO mice express significant preferences for 8% glucose and galactose.
Skn-1a (show POU2F3 Antibodies) is expressed in a minority of Mash1 (show ASCL1 Antibodies)-positive olfactory progenitor cells and a majority of Trpm5-expressing microvillous cells in the main olfactory epithelium.
The Trpm5 (but not T1r3 (show TAS1R3 Antibodies)) signaling is essential for starch preference, Trpm5 KO mice can learn to prefer starch based on its postoral effects.
This study show that olfactory sensory neurons expressing TRPM5 respond to pheromones, but not to regular odors through the opening of CNG (show CNGA1 Antibodies) channels leading to Ca2 (show CA2 Antibodies)+ gating of TRPM5
Evidence suggests that TRPM5 plays a role in mediating transduction for putative pheromones under conditions of reduced chemosensory input.
The results suggest that pharmacological or genetic alteration of TRPM5 activity modulates the benzamil-insensitive NaCl chorda tympani response and its modulation by TRPV1 (show TRPV1 Antibodies) agonists.
The findings of this study indicated that T1r3 (show TAS1R3 Antibodies) and Trpm5 play critical roles in carbohydrate-induced dietary obesity.
There may be a TRPM5-independent transduction pathway for detecting the taste of sweetening substances.
This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
transient receptor potential cation channel, subfamily M, member 5
, transient receptor potential cation channel subfamily M member 5-like
, MLSN1 and TRP-related
, MLSN1- and TRP-related gene 1 protein
, long transient receptor potential channel 5
, transient receptor potential cation channel subfamily M member 5
, long transient receptor potential-related channel 5