You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) Antibodies

Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Additionally we are shipping TRPM8 Proteins (9) and TRPM8 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRPM8 79054 Q7Z2W7
TRPM8 171382 Q8R4D5
TRPM8 171384 Q8R455
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-TRPM8 Antibodies at antibodies-online.com

Showing 10 out of 131 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-TRPM8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: ACHN cell lysate Immunohistochemistry with Prostate tissue at an antibody concentration of 5µg/ml using anti-TRPM8 antibody (ARP35357_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB TRPM8 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TRPM8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. TRPM8 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the TRPM8 antibody detected the TRPM8 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of TRPM8 Antibody (Center) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). TRPM8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TRPM8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB TRPM8 Antibody (Center) (ABIN655714) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of TRPM8 (arrow) using rabbit polyclonal TRPM8 Antibody (C-term)(ABIN392819).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the TRPM8 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with TRPM8 antibody (C-term) (ABIN392819), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of TRPM8 (arrow) using rabbit polyclonal TRPM8 Antibody (C-term C940)(ABIN392821).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the TRPM8 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with TRPM8 antibody (C-term C940) (ABIN392821), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of TRPM8 (arrow) using rabbit polyclonal TRPM8 Antibody (Center R536)(ABIN392820).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the TRPM8 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with TRPM8 antibody (Center R536) (ABIN392820), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details

TRPM8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,

, , , , , , , , , , , , , ,
Mouse (Murine) , ,
,

, , , , , , , , , , ,
Rat (Rattus) , , ,
, ,

, , , , , , , , , , , , , , ,

Top referenced anti-TRPM8 Antibodies

  1. Human Polyclonal TRPM8 Primary Antibody for EIA, IHC (p) - ABIN955342 : Yee, Zhou, Lee: Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma. in Cancer letters 2010 (PubMed)
    Show all 5 references for ABIN955342

  2. Human Polyclonal TRPM8 Primary Antibody for EIA, IF - ABIN955341 : Kühn, Witschas, Kühn, Lückhoff: Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN955341

  3. Human Polyclonal TRPM8 Primary Antibody for EIA, IHC (p) - ABIN360715 : Kiessling, Füssel, Schmitz, Stevanovic, Meye, Weigle, Klenk, Wirth, Rieber: Identification of an HLA-A*0201-restricted T-cell epitope derived from the prostate cancer-associated protein trp-p8. in The Prostate 2003 (PubMed)
    Show all 3 references for ABIN360715

  4. Human Polyclonal TRPM8 Primary Antibody for EIA, IHC (p) - ABIN360716 : Tsavaler, Shapero, Morkowski, Laus: Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. in Cancer research 2001 (PubMed)
    Show all 3 references for ABIN360716

  5. Human Polyclonal TRPM8 Primary Antibody for IF, IHC (p) - ABIN655714 : Gkika, Flourakis, Lemonnier, Prevarskaya: PSA reduces prostate cancer cell motility by stimulating TRPM8 activity and plasma membrane expression. in Oncogene 2010 (PubMed)

  6. Chicken Polyclonal TRPM8 Primary Antibody for IHC, WB - ABIN2776255 : Wondergem, Ecay, Mahieu, Owsianik, Nilius: HGF/SF and menthol increase human glioblastoma cell calcium and migration. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against TRPM8 Interaction Partners

Guinea Pig Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) interaction partners

  1. The role of TRPM8 in the Guinea-pig bladder-cooling reflex investigated using a novel TRPM8 antagonist

Human Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) interaction partners

  1. The data of this study provided evidence for decreased activity and expression level of TRPM8 in the presence of methylglyoxal.

  2. Study used a combination of molecular modeling and experimental techniques to examine the structure of the TRPM8 transmembrane and pore helix region including the conducting conformation of the selectivity filter

  3. Translational and clinical investigation to exploit TRPM8 as a molecular biomarker and therapeutic target is expected to make a positive impact on precision medicine in pancreatic cancer and other malignant diseases.

  4. Several TRPM8 variants appeared to be poorly expressed in transfected HEK293 cells compared with non-mutated TRPM8.

  5. The GC variant of the TRPM8: c.750G > C (rs11562975) polymorphism is associated with cold-induced airway hyperresponsiveness in patients with bronchial asthma.

  6. we found that the androgen-mediated TRPM8 channel activity is negatively regulated by the androgen receptor (show AR Antibodies) protein

  7. TRPM8 underlines the important physiologic role of the nose in temperature regulation, both in patients with allergy and those without allergy. Isometric contraction studies demonstrate the role of TRPM8 in regulating nasal patency and airway resistance.

  8. These results are the first to show that menthol directly binds to the TRPM8 sensing domain.

  9. Genetic polymorphisms in TRPM8 genes modify individual susceptibility to metabolic syndrome in a Turkish population.

  10. developed a new functional knockout mouse strain by deleting the pore domain of TRPM8 and demonstrated that eTRPM8 knockout impairs adaptation of the epidermis to low temperatures

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) interaction partners

  1. Reduced functional expression of TRPM8 in sensory neurons (due to VAMP7 (show VAMP7 Antibodies) knockout) is associated with deficits in cold avoidance and icilin-induced cold hypersensitivity.

  2. Report essential role of skin TRPM8 in a model of acute cold-induced urinary urgency.

  3. This study findings suggest the existence of VGLUT2 (show SLC17A6 Antibodies) (but not VGLUT1 (show SLC17A7 Antibodies))-mediated glutamate (show GRIN1 Antibodies) signaling in TRPM8+ neurons possibly underlying the cold-induced acute pain and hypersensitivity to cold following pulpal inflammation.

  4. Data suggest that blockage of transient receptor potential (TRP) channels TRPA1 (show TRPA1 Antibodies), TRPV4 (show TRPV4 Antibodies) and possibly TRPM8 may represent a therapeutic option for patients with colonic discomfort and pain.

  5. TRPM8 signaling in mucosal sensory neurons is indispensable for the regulation of innate inflammatory responses via the neuropeptide CGRP (show CALCA Antibodies).

  6. TRPM8-expressing dural afferent fibers undergo cell- and target tissue-specific axonal pruning during postnatal development.

  7. our findings suggest that temperature response thresholds in mice are dynamic. PLC (show HSPG2 Antibodies)-mediated hydrolysis of phosphoinositol 4,5-bisphosphate modulates TRPM8 activity and thereby regulates the response thresholds to cold stimuli.

  8. ZBTB20 (show ZBTB20 Antibodies) regulates nociception and pain sensation by modulating TRPV1 (show TRPV1 Antibodies), TRPA1 (show TRPA1 Antibodies) and TRPM8 expression in nociceptive sensory neurons.

  9. Increased expression of TRPM8 may contribute to the visceral hyperalgesia of experimental colitis.

  10. Study shows that oxidative stress affects urothelial function involving a TRPM8-mediated mechanism and these effects may have important implications for aging.

TRPM8 Antigen Profile

Protein Summary

Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.

Gene names and symbols associated with TRPM8

  • transient receptor potential cation channel, subfamily M, member 8 (TRPM8) antibody
  • transient receptor potential cation channel, subfamily M, member 8 (trpm8-b) antibody
  • transient receptor potential cation channel, subfamily M, member 8 (Trpm8) antibody
  • CMR1 antibody
  • LTrpC-6 antibody
  • LTRPC6 antibody
  • Trp-p8 antibody
  • TRPM8 antibody
  • trpm8b antibody
  • TRPP8 antibody

Protein level used designations for TRPM8

transient receptor potential cation channel, subfamily M, member 8 , transient receptor potential cation channel subfamily M member 8b , transient receptor potential cation channel subfamily M member 8 , transient potential cation channel subfamily M member 8 , LTrpC-6 , long transient receptor potential channel 6 , short form of the TRPM8 cationic channel , transient receptor potential p8 , transient receptor potential subfamily M member 8 , trp-p8 , TRP ion channel TRPM8 , transient receptor potential-p8 , cold menthol receptor 1 , cold/menthol receptor 1 , menthol receptor , transient receptor potential M8 protein , transient receptor potential cation channel, subfamily M, member 8 (predicted), 3 prime , transient receptor potential cation channel, subfamily M, member 8 (predicted), 5 prime

GENE ID SPECIES
100137386 Papio anubis
100302012 Xenopus laevis
100337634 Cavia porcellus
79054 Homo sapiens
171382 Mus musculus
171384 Rattus norvegicus
424025 Gallus gallus
486170 Canis lupus familiaris
541151 Bos taurus
100328692 Oryctolagus cuniculus
Selected quality suppliers for anti-TRPM8 (TRPM8) Antibodies
Did you look for something else?