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Transient Receptor Potential Cation Channel, Subfamily V, Member 5 Proteins (TRPV5)

TRPV5 is a member of the transient receptor family and the TrpV subfamily. Additionally we are shipping TRPV5 Antibodies (68) and TRPV5 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRPV5 194352 P69744
TRPV5 56302 Q9NQA5
Rat TRPV5 TRPV5 116469 Q9JIP0
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Top TRPV5 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

TRPV5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) Interaction Partners

Horse (Equine) Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) interaction partners

  1. TRPV5 and TRPV6 (show TRPV6 Proteins) were upregulated with time and passage in culture suggesting that a shift in the phenotype of the cells in monolayer culture alters the expression of these channels.

  2. In Equus caballus, TRPV5 mRNA is highly expressed in the kidney but scarce in the duodenum and heart. Protein expression followed a similar pattern.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) interaction partners

  1. A novel primary cell model with TRPV5-dependent Ca(2 (show CA2 Proteins)+) transport characteristics was successfully established.

  2. Phosphorylation of beta1-AR by PKA stimulates active Ca(2 (show CA2 Proteins)+)influx through TRPV5.

  3. The expression of TRPV5 channel is regulated by estrogen via estrogen receptor (show ESR1 Proteins) in osteoblasts.

  4. Uromodulin (show UMOD Proteins) upregulates TRPV5 by decreasing caveolin-1 (show CAV1 Proteins) dependent endocytosis of TRPV5.

  5. In colitis in mice, tumor necrosis factor (show TNF Proteins) and interferon-gamma (show IFNG Proteins) reduced expression of Klotho (show KL Proteins), which otherwise would protect TRPV5 from hypersialylation and cytokine-induced TRPV5 endocytosis, UBR4-dependent ubiquitination, degradation, and Ca(2 (show CA2 Proteins)+) wasting.

  6. The TRPV5 S682P mutant is a functionally significant factor in autosomal dominant hypercalciuria.

  7. promoter driven Cre recombinase (show RAG1 Proteins) expression will be useful for inducing DCT2 and CNT specific gene silencing of various channels, pumps, carriers, and receptors

  8. Calcitonin (show CALCA Proteins) augments the renal reabsorptive capacity for Ca(2 (show CA2 Proteins)+). This increase is likely to occur independently of TRPV5.

  9. TrpV5 mediates basal renal calcium absorption in null mutant mice lacking calcium channel beta3 subunits (CaVbeta3) and multimeric calcium channel entry via distal convoluted renal tubules.

  10. the key function of TRPV5 is in active Ca2 (show CA2 Proteins)+ reabsorption and it has an essential role in Ca2 (show CA2 Proteins)+ homeostasis

Human Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) interaction partners

  1. These findings indicate that the A563T variation induces structural, dynamical, and electrostatic changes in the TRPV5 pore, providing structural insight into the functional alterations associated with the A563T variation.

  2. Data found that a TRPV5 polymorphism (rs4236480) was observed to be associated with stone multiplicity of calcium nephrolithiasis, as the risk of stone multiplicity was higher in patients with the TT+CT genotype than in patients with the CC genotype

  3. High TRPV5 expression is aassociated with adenoma of parathyroid glands.

  4. Klotho (show KL Proteins) up-regulates TRPV5 from both the inside and outside of cells.

  5. Decreased expression of TRPV5 is associated with non-small cell lung cancer.

  6. Upregulating the expression of TRPV5 can be utilized to manipulate transmembrane Ca2 (show CA2 Proteins)+ transport, and may serve as an alternative for the treatment of Ca2 (show CA2 Proteins)+ balance-related diseases.

  7. These results suggest that TRPV5 and TRPV6 (show TRPV6 Proteins) are crucial gates controlling cadmium and zinc levels in the human body.

  8. these data showed that TRPV5/TRPV6 (show TRPV6 Proteins) in human lymphocytes are functionally active, and their activity is associated with proliferative status of blood cells.

  9. Data indicate that transient receptor potential vanilloid type 5 (TRPV5) plasma membrane retention is regulated via lipid rafts.

  10. TRPML3 and TRPV5 heteromers could have a biological function

Rabbit Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) interaction partners

  1. mutation of a pore helix residue glutamate-535 to glutamine (E535Q) enhances the sensitivity of the channel to inhibition by extracellular protons

  2. Results suggest that intracellular acidification directly inhibits TRPV5 by causing a conformational change(s) leading to a decrease of open probability of TRPV5 as well as of the single-channel conductance.

  3. Activation of the CaR stimulates TRPV5-mediated Ca(2+) influx via a PMA-insensitive PKC isoform pathway.

TRPV5 Protein Profile

Protein Summary

This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.

Gene names and symbols associated with TRPV5

  • transient receptor potential cation channel, subfamily V, member 5 (TRPV5)
  • transient receptor potential cation channel, subfamily V, member 5 (trpv5)
  • transient receptor potential cation channel, subfamily V, member 5 (Trpv5)
  • CaT2 protein
  • D630033B11 protein
  • ECAC protein
  • Ecac1 protein
  • OTRPC3 protein
  • TRPV5 protein

Protein level used designations for TRPV5

transient receptor potential cation channel, subfamily V, member 5 , epithelial calcium channel 1 , transient receptor potential cation channel subfamily V member 5 , OTRPC3 , calcium transport protein 2 , osm-9-like TRP channel 3 , ECaC , calcium transporter 2 , ECaC1

GENE ID SPECIES
463800 Pan troglodytes
100011049 Monodelphis domestica
100034071 Equus caballus
100379874 Xenopus (Silurana) tropicalis
100596333 Nomascus leucogenys
194352 Mus musculus
56302 Homo sapiens
116469 Rattus norvegicus
482744 Canis lupus familiaris
524365 Bos taurus
100009364 Oryctolagus cuniculus
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