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Transition Protein 1 (During Histone To Protamine Replacement) (TNP1) ELISA Kits

Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880\; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008].. Additionally we are shipping TNP1 Antibodies (27) and TNP1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse TNP1 TNP1 21958 P10856
Anti-Rat TNP1 TNP1 24839 P02317
Anti-Human TNP1 TNP1 7141 P09430
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More ELISA Kits for TNP1 Interaction Partners

Mouse (Murine) Transition Protein 1 (During Histone To Protamine Replacement) (TNP1) interaction partners

  1. The elevated levels of the remaining TP in Tnp-mutant mice appeared to be a consequence of the prolonged nucleus retention, rather than increased synthesis.

  2. Epididymal sperm from the Tnp1 null genotypes demonstrated a general decrease in normal morphology, motility, chromatin condensation, and degree of protamine 2 (show PRM2 ELISA Kits) processing with decreasing levels of transition proteins in mutant sperm.

  3. JHDM2A (show KDM3A ELISA Kits) directly binds to and controls the expression of transition nuclear protein 1 (show NUPR1 ELISA Kits) (Tnp1) and protamine 1 (Prm1 (show PRM1 ELISA Kits)) genes, the products of which are required for packaging and condensation of sperm chromatin

Human Transition Protein 1 (During Histone To Protamine Replacement) (TNP1) interaction partners

  1. Among Systemic lupus erythematosus patients, 63.6% and 45.5% of those with lupus nephritis were positive for anti-RRP8 (show RRP8 ELISA Kits) and anti-TNP1 antibodies, compared with 12.5% and 9.4% of Systemic lupus erythematosus patients without nephritis, respectively.

  2. frequency of the haplotype GCG (show GCG ELISA Kits) (H3) was increased in azoospermic men compared with fertile men. expression analysis of the TNP1 gene in obstructive azoospermic men showed that haplotypes of the TNP1 gene do not affect its expression level.

  3. a deletion of 15 nucleotides encompassing the recognition site for the cAMP response element transcription factor was found in the 5'-promoter region of the TNP1 gene in infertile men; this deletion reduces TNP1 expression and may cause infertility

  4. We found significantly lower levels of HILS1, TNP1, and TNP2 (show TNP2 ELISA Kits) transcripts in spermatozoa from asthenozoospermic men compared to normozoospermic men.

  5. The TNP1 contributes not only to successful fertilization, but may has an important impact in development of preimplantation embryos.

  6. The presence of transition proteins (TP1 (show RPLP2 ELISA Kits) and/or TP2 (show TERT ELISA Kits)) in spermatids in semen indicates inhibition in the differentiation pathway from round spermatids to spermatozoa in infertile men.

Cow (Bovine) Transition Protein 1 (During Histone To Protamine Replacement) (TNP1) interaction partners

  1. We propose that SNPs on the TNP1 3'-UTR (show UTS2R ELISA Kits) may help select semen quality trait in Chinese Holstein bulls in the dairy industry.

TNP1 Antigen Profile

Antigen Summary

Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880\; PRM2, MIM 182890) (Luerssen et al., 1990

Gene names and symbols associated with TNP1

  • transition protein 1 (during histone to protamine replacement) (TNP1) antibody
  • transition protein 1 (during histone to protamine replacement) (LOC100349146) antibody
  • spermatid nuclear transition protein 1-like (LOC100513764) antibody
  • transition protein 1 (Tnp1) antibody
  • Stp-1 antibody
  • TNP1 antibody
  • Tp-1 antibody
  • TP1 antibody

Protein level used designations for TNP1

transition protein 1 (during histone to protamine replacement) , Spermatid nuclear transition protein 1 , spermatid nuclear transition protein 1 , STP-1 , TP-1 , testis-specific basic protein

GENE ID SPECIES
696593 Macaca mulatta
100349146 Oryctolagus cuniculus
740418 Pan troglodytes
100630835 Equus caballus
100513764 Sus scrofa
21958 Mus musculus
24839 Rattus norvegicus
7141 Homo sapiens
100686780 Canis lupus familiaris
407743 Sus scrofa
281537 Bos taurus
101108026 Ovis aries
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