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Transition Protein 2 (During Histone To Protamine Replacement) Proteins (TNP2)

a zinc binding nuclear protein in sperm [RGD, Feb 2006].. Additionally we are shipping TNP2 Antibodies (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNP2 21959 P11378
TNP2 24840 P11101
TNP2 7142 Q05952
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Top TNP2 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,218.33
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$2,266.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,275.17
Details
Yeast Pan paniscus His tag   1 mg Log in to see 56 to 66 Days
$2,277.00
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,277.00
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days
$2,289.83
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,289.83
Details
Yeast Pongo pygmaeus His tag   1 mg Log in to see 56 to 66 Days
$2,293.50
Details

TNP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human

More Proteins for Transition Protein 2 (During Histone To Protamine Replacement) (TNP2) Interaction Partners

Mouse (Murine) Transition Protein 2 (During Histone To Protamine Replacement) (TNP2) interaction partners

  1. The association of Tp2 (show TERT Proteins) expression via binding to the conserved RNA binding motifs of GRTH (show DDX25 Proteins) protein and the basis for understanding GRTH (show DDX25 Proteins) in the regulation of the genes essential for germ cell elongation and completion of spermatogenesis is revealed.

  2. Testis-specific (show AIF1 Proteins) miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25 (show DDX25 Proteins))-null mice silences transition protein 2 and protamine 2 (show PRM2 Proteins) messages at sites within coding region: implications of its role in germ cell development.

  3. Cannabinoid receptor 1 influences chromatin remodeling in mouse spermatids by affecting content of transition protein 2 mRNA.

  4. The elevated levels of the remaining TP in Tnp-mutant mice appeared to be a consequence of the prolonged nucleus retention, rather than increased synthesis

  5. Epididymal sperm from Tnp2 null genotypes demonstrated a general decrease in normal morphology, motility, chromatin condensation, and degree of protamine 2 (show PRM2 Proteins) processing with decreasing levels of transition proteins in mutant sperm.

  6. Specific microRNAs, such as Mirn122a, could be involved in the posttranscriptional regulation of mRNAs such as Tnp2 in the mammalian testis.

  7. These results show clearly that a strict temporal and stage-specific Tnp2 translation is necessary for the correct differentiation of round spermatids into mature spermatozoa and for male fertility.

  8. Data show that Parp2 (show PARP2 Proteins) interacts significantly with both the transition protein TP2 (show TERT Proteins) and the transition chaperone HSPA2, whereas Parp1 (show PARP1 Proteins) binds weakly to HSPA2 (show HSPA2 Proteins).

Human Transition Protein 2 (During Histone To Protamine Replacement) (TNP2) interaction partners

  1. the quantity of PRM1 (show PRM1 Proteins), PRM2 (show PRM2 Proteins), and TNP2 transcripts and the PRM1 (show PRM1 Proteins)/PRM2 (show PRM2 Proteins) mRNA ratio affect spermiogenesis, sperm morphology

  2. MiR (show MLXIP Proteins)-122 may influence spermatozoa-like cells by suppressing TNP2 expression and inhibiting the expression of proteins associated with sperm development.

  3. analysis of the TNP2 gene did not show any association with infertility.

  4. We found significantly lower levels of HILS1, TNP1 (show TNP1 Proteins), and TNP2 transcripts in spermatozoa from asthenozoospermic men compared to normozoospermic men.

  5. The presence of transition proteins (TP1 (show RPLP2 Proteins) and/or TP2 (show TERT Proteins)) in spermatids in semen indicates inhibition in the differentiation pathway from round spermatids to spermatozoa in infertile men.

  6. Acetylation of transition protein 2 (TP2) by KAT3B (p300 (show EP300 Proteins)) alters its DNA condensation property and interaction with putative histone chaperone NPM3 (show NPM3 Proteins).

Cow (Bovine) Transition Protein 2 (During Histone To Protamine Replacement) (TNP2) interaction partners

  1. SNP g.1536 C>T in the TNP2 3'-UTR, which altered the binding of TNP2 with bta-miR (show MYLIP Proteins)-154, was found to be associated with the semen quality traits of Chinese Holstein bulls

TNP2 Protein Profile

Protein Summary

a zinc binding nuclear protein in sperm

Gene names and symbols associated with TNP2

  • transition protein 2 (during histone to protamine replacement) (TNP2)
  • transition protein 2 (Tnp2)
  • Tp-2 protein
  • TP2 protein

Protein level used designations for TNP2

nuclear transition protein 2 , transition protein 2 (alt.) , TP-2 , TP2 , haploid expressed, male germcell specific, chromatin binding

GENE ID SPECIES
100189599 Equus caballus
21959 Mus musculus
24840 Rattus norvegicus
7142 Homo sapiens
281538 Bos taurus
479849 Canis lupus familiaris
406180 Sus scrofa
467904 Pan troglodytes
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