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TSNAX encodes a protein which specifically interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. Additionally we are shipping Translin-Associated Factor X Antibodies (39) and Translin-Associated Factor X Proteins (8) and many more products for this protein.
TSNAX protein is known to form a brain enriched complex with translin (show TSN ELISA Kits), that can bind single-stranded DNA and RNA through which it is involved in protein regulation.
High chimeric TSNAX-DISC1 (show DISC1 ELISA Kits) resulting from intergenic splicing is associated with endometrial carcinoma.
LIS1 and TSNAX genes are not associated with susceptibility to bipolar I disorder in Chinese Han population.
Data show a novel role of phospholipase Cbeta1 (PLCbeta1) in gene regulation through translin-associated factor X (TRAX) association.
Our results provide further evidence for sex-dependent effects of the TSNAX/DISC1 (show DISC1 ELISA Kits) locus in the aetiology of schizophrenia and bipolar affective disorder
TRAX binds to ssDNA and two regions in TRAX, designated TRAXB2 and TRAXB3, mediate nucleic acid binding activity of the trax-translin (show TSN ELISA Kits) heteromeric complex.
C3PO (show TSN ELISA Kits) endonuclease is an asymmetric octamer barrel consisting of six translin (show TSN ELISA Kits) and two TRAX subunits which activates RISC (show SCPEP1 ELISA Kits) by degrading the Ago2 (show EIF2C2 ELISA Kits)-nicked passenger strand of siRNA.
The results of this suggested an association between the TSNAX-DISC1 (show DISC1 ELISA Kits) region and both forms of affective disorders.
Results suggest that rs766288 in translin-associated factor X gene may play a role in the pathophysiology of female major depressive disorder in the Japanese population.
TRAX is post-transcriptionally stabilized by TB-RBP (show TSN ELISA Kits) and both proteins are needed for normal cell proliferation
TRAX is required for DNA repair, by interacting with activated ATM (show ATM ELISA Kits) and protects cells from genotoxic stress-induced apoptosis.
trax acts to regulate translin's RNA and DNA binding affinities as part of a cellular RNA trafficking mechanism.
The TB-RBP (show TSN ELISA Kits)-related and -interacting protein Translin-associated factor X was reduced to 50% normal levels in heterozygotes and was absent in TB-RBP (show TSN ELISA Kits)-null animals.
subcellular locations of TB-RBP (show TSN ELISA Kits) and TRAX in male germ cells are modulated by the relative ratios of TRAX and TB-RBP (show TSN ELISA Kits)
Trax was found to accumulate in the Golgi complex of mid-late pachytene spermatocytes
This gene encodes a protein which specifically interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. The encoded protein contains bipartite nuclear targeting sequences that may provide nuclear transport for translin, which lacks any nuclear targeting motifs.
translin-associated protein X
, translin-associated factor X
, translin-like protein