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anti-Translocation Protein 1 (TLOC1) Antibodies

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Additionally we are shipping Translocation Protein 1 Proteins (7) and Translocation Protein 1 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TLOC1 7095 Q99442
TLOC1 69276 Q8BU14
TLOC1 294912  
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Top anti-Translocation Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SEC62 antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of SEC62 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of SEC62 Antibody (N-term) Cat.-No AP53834PU-N in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the SEC62 antibody detected the SEC62 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunohistochemistry of SEC62 in mouse brain tissue with SEC62 antibody at 5 ug/mL. Western blot analysis of SEC62 in rat brain tissue lysate with SEC62 antibody at (A) 0.5 and (B) 1 ug/mL. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB SEC62 Antibody (N-term)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SEC62 antibody detected the SEC62 protein (arrow). SEC62 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SEC62 Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB   50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of SEC62 in rat brain tissue lysate with SEC62 antibody at (A) 0.5 and (B) 1 µg/mL. 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

TLOC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-Translocation Protein 1 Antibodies

  1. Human Polyclonal TLOC1 Primary Antibody for EIA, IHC (p) - ABIN954706 : Jung, Kindich, Kamradt, Jung, Müller, Schulz, Engers, Unteregger, Stöckle, Zimmermann, Wullich: Genomic and expression analysis of the 3q25-q26 amplification unit reveals TLOC1/SEC62 as a probable target gene in prostate cancer. in Molecular cancer research : MCR 2006 (PubMed)
    Show all 4 references for ABIN954706

  2. Human Polyclonal TLOC1 Primary Antibody for EIA, IF - ABIN1450053 : Deshaies, Schekman: SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum. in The Journal of cell biology 1990 (PubMed)
    Show all 3 references for ABIN1450053

More Antibodies against Translocation Protein 1 Interaction Partners

Human Translocation Protein 1 (TLOC1) interaction partners

  1. these studies identify TLOC1 and SKIL (show SKIL Antibodies) as driver genes at 3q26 and more broadly suggest that cooperating genes may be coamplified in other regions with somatic copy number gain.

  2. Sec62 overproduction significantly correlates with reduced non-small lung cancer patient survival.

  3. Phosphorylation of Sec63 (show SEC63 Antibodies) by CK2 (show CSNK2A1 Antibodies) enhanced its binding to Sec62

  4. Silencing the SEC62 gene inhibits post-translational transport of small presecretory proteins into endoplasmic reticulum.

  5. the Sec62-dependent translocation pathway serves as a fail-safe mechanism to ensure efficient secretion of small proteins and provides cells with an opportunity to regulate secretion of small proteins independent of the signal recognition particle pathway

  6. These results revealed that cyclin B1 (show CCNB1 Antibodies) and Sec62 may be candidate biomarkers and potential therapeutic targets for HBV-related HCC (show FAM126A Antibodies) recurrence after surgery.

  7. The results indicate that SEC62 represents a potential candidate oncogene (show RAB1A Antibodies) in the amplified 3q region in cases of non-small cell lung cancer.

  8. Our data indicate a crucial function of Sec62 in the response to thapsigargin-induced endoplasmic reticulum stress.

  9. after silencing of SEC62 the cell migration and the invasive potential of the cells was blocked or at least dramatically reduced while cell viability was hardly affected. SEC62 gene may indeed be considered a target gene in the therapy of various tumors

  10. The gene TLOC1/SEC62 revealed the highest frequency (50%) of copy number gains in the prostate cancer and was found to be up-regulated at the mRNA level.

Mouse (Murine) Translocation Protein 1 (TLOC1) interaction partners

  1. Interaction of ribosomes and Sec62 with the core Sec61 (show SEC61A1 Antibodies) translocon is mutually exclusive.

  2. The Sec62 protein plays a role in post-translational transport of presecretory proteins into endoplasmic reticulum.

Translocation Protein 1 (TLOC1) Antigen Profile

Protein Summary

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Gene names and symbols associated with TLOC1

  • SEC62 homolog (sec62) antibody
  • SEC62 homolog (S. cerevisiae) (SEC62) antibody
  • SEC62 homolog (S. cerevisiae) (sec62) antibody
  • membrane unit of ER protein translocation apparatus (SEC62) antibody
  • SEC62 homolog (S. cerevisiae) (Sec62) antibody
  • 3100002M17Rik antibody
  • Ab2-292 antibody
  • AI844545 antibody
  • AW545092 antibody
  • Dtrp1 antibody
  • HTP1 antibody
  • Tloc1 antibody
  • TP-1 antibody
  • wu:fb57b06 antibody
  • zgc:114073 antibody

Protein level used designations for TLOC1

translocation protein 1 , translocation protein SEC62 , fb57b06 , uncharacterized protein LOC696989 , hypothetical protein , hTP-1 , membrane protein SEC62, S.cerevisiae, homolog of , TP-1

GENE ID SPECIES
446676 Xenopus laevis
538938 Bos taurus
563660 Danio rerio
696989 Macaca mulatta
744481 Pan troglodytes
100125961 Sus scrofa
3637124 Candida albicans SC5314
7095 Homo sapiens
69276 Mus musculus
294912 Rattus norvegicus
424993 Gallus gallus
609416 Canis lupus familiaris
100174729 Pongo abelii
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