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anti-Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) (TMED10) Antibodies

TMED10 is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. Additionally we are shipping TMED10 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TMED10 10972 P49755
TMED10 68581 Q9D1D4
TMED10 84599 Q63584
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Top anti-TMED10 Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-TMED10 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Small Intestine WB Suggested Anti-TMED10  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human Small Intestine 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of TMP21 in human brain tissue with this product at 2.5 μg/ml. Western blot analysis of TMP21 in Raji cell lysate with this product at (A) 0.5 and (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of TMP21 in human brain tissue with this product at 5 μg/ml. Western blot analysis of TMP21 in mouse brain tissue lysate with this product at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB IKK(alpha/beta) Antibody (S176/180)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the IKK antibody detected the IKK protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Prostate (formalin-fixed, paraffin-embedded) stained with TMED10 antibody ABIN214004 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with TMED10 antibody ABIN214004 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Breast (formalin-fixed, paraffin-embedded) stained with TMED10 antibody ABIN214530 at 3 ng/ul followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Prostate (formalin-fixed, paraffin-embedded) stained with TMED10 antibody ABIN214530 at 3 ng/ul followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details

TMED10 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TMED10 Antibodies

  1. Human Polyclonal TMED10 Primary Antibody for IHC, ELISA - ABIN1003291 : Blum, Feick, Puype, Vandekerckhove, Klengel, Nastainczyk, Schulz: Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking. in The Journal of biological chemistry 1996 (PubMed)
    Show all 4 references for ABIN1003291

  2. Human Polyclonal TMED10 Primary Antibody for EIA, IHC (p) - ABIN500992 : Selkoe: The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. in Trends in cell biology 1999 (PubMed)
    Show all 4 references for ABIN500992

  3. Human Polyclonal TMED10 Primary Antibody for EIA, IHC (p) - ABIN500990 : Chen, Hasegawa, Schmitt-Ulms, Kawarai, Bohm, Katayama, Gu, Sanjo, Glista, Rogaeva, Wakutani, Pardossi-Piquard, Ruan, Tandon, Checler, Marambaud, Hansen, Westaway, St George-Hyslop, Fraser: TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. in Nature 2006 (PubMed)
    Show all 3 references for ABIN500990

  4. Chicken Polyclonal TMED10 Primary Antibody for WB - ABIN2787806 : Dolcini, Dunys, Sevalle, Chen, Guillot-Sestier, St George-Hyslop, Fraser, Checler: TMP21 regulates Abeta production but does not affect caspase-3, p53, and neprilysin. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against TMED10 Interaction Partners

Human Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) (TMED10) interaction partners

  1. TMP21 modulates cell growth in papillary thyroid cancer cells by inducing autophagy, which may be associated with activation of AMPK (show PRKAA1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway.

  2. Study demonstrates that NleF binds to the human Tmp21 protein and subsequently disrupts intracellular protein (show CKAP2 Antibodies) trafficking.

  3. Data show that the level of p23 expression is critical for neuronal function, and p23 overexpression initiates a cascade in brainstem that leads to severe motor deficits and other neurological problems, culminating in premature death.

  4. Results suggest that Tmp21 is a novel protein that preferentially binds to Beta(2)-microglobulin-free MHC-I heavy chains.

  5. p23 acts as an anchoring protein that retains PKCdelta (show PKCd Antibodies) at the perinuclear region, thus limiting the availability of this kinase for activation in response to stimuli.

  6. Transmembrane protein 23 (show SGMS1 Antibodies) and p24A differentially control G-protein coupled receptor (show ADRA1A Antibodies) trafficking and signaling in astrocytes.

  7. These results demonstrate that p23/Tmp21 acts as an anchor that distinctively modulates compartmentalization of C1 domain-containing proteins, and it plays an essential role in beta2-chimaerin (show CHN1 Antibodies) relocalization.

  8. TMP21, a member of the p24 cargo protein family, is a component of presenilin complexes and differentially regulates gamma-secretase cleavage without affecting epsilon-secretase activity

  9. TMP21 behaves as a regulator of gamma- but not epsilon-cleavages of beta-amyloid precursor protein generated by presenilin-dependent gamma-secretase complex.

  10. p23 is widely distributed throughout the frontal cortex, hippocampus and cerebellum of control and Alzheimer disease (AD)brains; steady-state p23 levels are reduced in the brains of individuals with AD.

Mouse (Murine) Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) (TMED10) interaction partners

  1. These findings suggest that a fraction of p23 (show CDK5R1 Antibodies) enters post-Golgi compartments and may function in the biogenesis and/or quality control of SGs (show SKI Antibodies).

  2. High levels of p23 (show CDK5R1 Antibodies) expression are found in embryonic mouse brain, but the steady-state p23 (show CDK5R1 Antibodies) levels gradually decline after birth to the lower adult level.

TMED10 Antigen Profile

Protein Summary

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Gene names and symbols associated with TMED10

  • transmembrane emp24-like trafficking protein 10 (tmed10) antibody
  • transmembrane emp24-like trafficking protein 10 (yeast) (TMED10) antibody
  • transmembrane emp24-like trafficking protein 10 (yeast) (Tmed10) antibody
  • transmembrane emp24-like trafficking protein 10 (yeast) (tmed10) antibody
  • 1110014C03Rik antibody
  • fe06g04 antibody
  • p23 antibody
  • P24(DELTA) antibody
  • p24delta1 antibody
  • S31I125 antibody
  • S31III125 antibody
  • Tmp-21-I antibody
  • Tmp21 antibody
  • wu:fb98e10 antibody
  • wu:fe06g04 antibody
  • zgc:85681 antibody

Protein level used designations for TMED10

transmembrane protein tmp21 , 21 kDa transmembrane trafficking protein , 21 kDa transmembrane-trafficking protein , p24 family protein delta-1 , p24delta , p24delta1 , transmembrane emp24 domain-containing protein 10 , transmembrane protein Tmp21 , transmembrane trafficking protein , integral membrane protein Tmp21-I (p23) , transmembrane trafficking protein 21 , p24 delta 1 , integral membrane protein p23

GENE ID SPECIES
379442 Xenopus laevis
10972 Homo sapiens
68581 Mus musculus
84599 Rattus norvegicus
529761 Bos taurus
326716 Danio rerio
423362 Gallus gallus
100009296 Oryctolagus cuniculus
610559 Canis lupus familiaris
Selected quality suppliers for anti-TMED10 (TMED10) Antibodies
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