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anti-Transmembrane Protease, serine 2 (TMPRSS2) Antibodies

TMPRSS2 encodes a protein that belongs to the serine protease family. Additionally we are shipping TMPRSS2 Kits (14) and TMPRSS2 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TMPRSS2 7113 O15393
TMPRSS2 156435  
TMPRSS2 50528 Q9JIQ8
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Top anti-TMPRSS2 Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TMPRSS2 antibody (Center) in HepG2 cell line lysates (35ug/lane). TMPRSS2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TMPRSS2 antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). TMPRSS2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of TMPRSS2 antibody (Center) (ABIN391564) in HepG2 cell line lysates (35 µg/lane). TMPRSS2 (arrow) was detected using the purified polyclonal antibody. TMPRSS2 Antibody (Center) (ABIN391564) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of TMPRSS2 Antibody (N-term) (ABIN391563) in 293, NCI-H460 cell line lysates (35 µg/lane). TMPRSS2 (arrow) was detected using the purified polyclonal antibody. TMPRSS2 Antibody (N-term) (ABIN391563) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lung labeled with Anti PRSS10/TMPRSS2 Polyclonal Antibody, Unconjugated (ABIN716876) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TMPRSS2 is approximately 3ng/ml as a capture antibody. Western Blot detection against Immunogen (37.84 KDa) . 100 μg Log in to see 9 Days
$430.00
Details

TMPRSS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TMPRSS2 Antibodies

  1. Human Polyclonal TMPRSS2 Primary Antibody for EIA, WB - ABIN453424 : Gopalan, Leversha, Satagopan, Zhou, Al-Ahmadie, Fine, Eastham, Scardino, Scher, Tickoo, Reuter, Gerald: TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. in Cancer research 2009 (PubMed)
    Show all 2 references for ABIN453424

  2. Human Polyclonal TMPRSS2 Primary Antibody for EIA, WB - ABIN453423 : Hofer, Kuefer, Maier, Herkommer, Perner, Demichelis, Paiss, Vogel, Rubin, Hoegel: Genome-wide linkage analysis of TMPRSS2-ERG fusion in familial prostate cancer. in Cancer research 2009 (PubMed)
    Show all 2 references for ABIN453423

  3. Human Polyclonal TMPRSS2 Primary Antibody for EIA, WB - ABIN375252 : Tomlins, Laxman, Dhanasekaran, Helgeson, Cao, Morris, Menon, Jing, Cao, Han, Yu, Wang, Montie, Rubin, Pienta, Roulston, Shah, Varambally, Mehra, Chinnaiyan: Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. in Nature 2007 (PubMed)

More Antibodies against TMPRSS2 Interaction Partners

Human Transmembrane Protease, serine 2 (TMPRSS2) interaction partners

  1. Aspirin was associated with a significant reduction in the relative risk of TMPRSS2:ERG (show ERG Antibodies) (T2E )fusion positive, but not T2E negative

  2. the type II transmembrane serine protease (show TMPRSS11E Antibodies) TMPRSS2 was able to activate hemagglutinin (show HA Antibodies) for cell entry indicating that bat (show BAAT Antibodies) influenza A virus can utilize human proteases for hemagglutinin (show HA Antibodies) activation.

  3. The relatively low rate of ERG (show ERG Antibodies)-positive prostatic intraepithelial neoplasia counts in favor of the limited role of chimeric transcript TMPRSS2/ERG (show ERG Antibodies) in the differential diagnosis of prostatic intraepithelial neoplasia

  4. TMPRSS2 isoform 1 is expressed in viral target cells.

  5. The TMPRSS2-ERG (show ERG Antibodies) Gene Fusion Blocks XRCC4 (show XRCC4 Antibodies)-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP (show COL11A2 Antibodies) Inhibition

  6. The potential for TMPRSS2:ERG (show ERG Antibodies) gene fusion, detected by IHC, to modify the role of PTEN (show PTEN Antibodies) loss in lethal progression of prostate cancer.

  7. Results indicate that PTEN (show PTEN Antibodies) loss occurs in cooperation with TMPRSS2-ERG fusion in prostate cancer and the majority of the samples harbor TMPRSS2-ERG fusion as well as PTEN (show PTEN Antibodies) gene deletion.

  8. Elucidation of ERG (show ERG Antibodies) regulation of ABEs in castration-resistant prostate cancer (CRPC) may help to stratify TMPRSS2-ERG fusion-positive prostate cancer patients in the clinic for anti-androgen receptor (show AR Antibodies)-driven therapies.

  9. these data show that the androgen-driven events causing TMPRSS2-ERG (show ERG Antibodies) fusions and other rearrangements of androgen-dependent genes in prostate epithelial cells of young patients preferentially lead to low-grade (and not high-grade) prostate cancer.

  10. Genetic inhibition of TMPRSS2-ERG (show ERG Antibodies) junction oncogene (show RAB1A Antibodies) in prostate cancer by means of siRNA has strong antineoplastic effect in a mouse model and in vitro.

Mouse (Murine) Transmembrane Protease, serine 2 (TMPRSS2) interaction partners

  1. Genetic inhibition of TMPRSS2-ERG (show ERG Antibodies) junction oncogene (show RAB1A Antibodies) in prostate cancer by means of siRNA has strong antineoplastic effect in a mouse model and in vitro.

  2. The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis

  3. TMPRSS2 as a host cell factor essential for viral spread and pathogenesis of mono-basic H1N1 and H3N2 influenza A viruses.

  4. These results demonstrate that TMPRSS2 expression is essential for influenza A virus replication in vivo.

  5. These data demonstrate that TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 and H1N1 influenza virus in mice.

  6. Loss of TMPRSS2 serine protease (show F2 Antibodies) activity does not influence fertility, reduce survival, result in prostate hyperplasia or carcinoma, or alter prostatic luminal epithelial cell regrowth following castration and androgen replacement.

TMPRSS2 Antigen Profile

Protein Summary

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TMPRSS2

  • transmembrane protease serine 2-like (LOC100739411) antibody
  • transmembrane protease, serine 2 (TMPRSS2) antibody
  • transmembrane protease, serine 2 (Tmprss2) antibody
  • transmembrane protease, serine 2-like (LOC100337870) antibody
  • D16Ertd61e antibody
  • PP9284 antibody
  • PRSS10 antibody

Protein level used designations for TMPRSS2

epitheliasin , serine protease 10 , transmembrane protease serine 2 , plasmic transmembrane protein X

GENE ID SPECIES
100739411 Sus scrofa
7113 Homo sapiens
156435 Rattus norvegicus
50528 Mus musculus
418528 Gallus gallus
100732077 Cavia porcellus
100337870 Oryctolagus cuniculus
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