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TMPRSS2 encodes a protein that belongs to the serine protease family. Additionally we are shipping TMPRSS2 Kits (17) and TMPRSS2 Proteins (12) and many more products for this protein.
Showing 10 out of 64 products:
Human Polyclonal TMPRSS2 Primary Antibody for EIA, WB - ABIN453424
Gopalan, Leversha, Satagopan, Zhou, Al-Ahmadie, Fine, Eastham, Scardino, Scher, Tickoo, Reuter, Gerald: TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. in Cancer research 2009
Show all 2 references for ABIN453424
Human Polyclonal TMPRSS2 Primary Antibody for EIA, WB - ABIN453423
Hofer, Kuefer, Maier, Herkommer, Perner, Demichelis, Paiss, Vogel, Rubin, Hoegel: Genome-wide linkage analysis of TMPRSS2-ERG fusion in familial prostate cancer. in Cancer research 2009
Show all 2 references for ABIN453423
Human Polyclonal TMPRSS2 Primary Antibody for ELISA, WB - ABIN449738
Tomlins, Laxman, Dhanasekaran, Helgeson, Cao, Morris, Menon, Jing, Cao, Han, Yu, Wang, Montie, Rubin, Pienta, Roulston, Shah, Varambally, Mehra, Chinnaiyan: Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. in Nature 2007
TMPRSS2-ERG (show ERG Antibodies) role in prostate cancer invasiveness and regulation of MMP-9 (show MMP9 Antibodies) and plexin B1 (show PLXNB1 Antibodies).
Our results indicate that it is possible to predict pT3 (show ZNF135 Antibodies) stage at final histology from TMPRSS2:ERG (show ERG Antibodies) gene fusion at initial core needle biopsy. FISH determination of TMPRSS2:ERG (show ERG Antibodies) gene fusion may be particularly useful for patients scheduled to undergo a radical prostatectomy in order to improve oncological and functional results
Data show there was a good agreement of transcriptional regulator ERG (show ERG Antibodies) protein (ERG (show ERG Antibodies)) immunostaining with the presence of TMPRSS2:ERG (show ERG Antibodies) fusion protein.
A combination of high preoperative serum PSA (show PLAG1 Antibodies) and high expression of TMPRSS2-ERG (show ERG Antibodies) could be promising in distinguishing those tumors that are aggressive and life-threatening.
Studies showed that urinary TMPRSS2:ERG (show ERG Antibodies) transcripts seem to be indicative of Prostate cancer aggressiveness upon biopsy. [review]
Aspirin was associated with a significant reduction in the relative risk of TMPRSS2:ERG (show ERG Antibodies) (T2E )fusion positive, but not T2E negative
the type II transmembrane serine protease (show TMPRSS11E Antibodies) TMPRSS2 was able to activate hemagglutinin (show HA Antibodies) for cell entry indicating that bat (show BAAT Antibodies) influenza A virus can utilize human proteases for hemagglutinin (show HA Antibodies) activation.
The relatively low rate of ERG (show ERG Antibodies)-positive prostatic intraepithelial neoplasia counts in favor of the limited role of chimeric transcript TMPRSS2/ERG (show ERG Antibodies) in the differential diagnosis of prostatic intraepithelial neoplasia
TMPRSS2 isoform 1 is expressed in viral target cells.
The TMPRSS2-ERG (show ERG Antibodies) Gene Fusion Blocks XRCC4 (show XRCC4 Antibodies)-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP (show COL11A2 Antibodies) Inhibition
Genetic inhibition of TMPRSS2-ERG (show ERG Antibodies) junction oncogene (show RAB1A Antibodies) in prostate cancer by means of siRNA has strong antineoplastic effect in a mouse model and in vitro.
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis
TMPRSS2 as a host cell factor essential for viral spread and pathogenesis of mono-basic H1N1 and H3N2 influenza A viruses.
These results demonstrate that TMPRSS2 expression is essential for influenza A virus replication in vivo.
These data demonstrate that TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 and H1N1 influenza virus in mice.
Loss of TMPRSS2 serine protease (show F2 Antibodies) activity does not influence fertility, reduce survival, result in prostate hyperplasia or carcinoma, or alter prostatic luminal epithelial cell regrowth following castration and androgen replacement.
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, serine protease 10
, transmembrane protease serine 2
, plasmic transmembrane protein X