anti-Transmembrane Protease, serine 2 (TMPRSS2) Antibodies

TMPRSS2 encodes a protein that belongs to the serine protease family. Additionally we are shipping TMPRSS2 Kits (18) and TMPRSS2 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TMPRSS2 7113 O15393
TMPRSS2 156435  
TMPRSS2 50528 Q9JIQ8
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Top anti-TMPRSS2 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TMPRSS2 antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). TMPRSS2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TMPRSS2 antibody (Center) in HepG2 cell line lysates (35ug/lane). TMPRSS2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of TMPRSS2 antibody (Center) (ABIN391564) in HepG2 cell line lysates (35 µg/lane). TMPRSS2 (arrow) was detected using the purified polyclonal antibody. TMPRSS2 Antibody (Center) (ABIN391564) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of TMPRSS2 Antibody (N-term) (ABIN391563) in 293, NCI-H460 cell line lysates (35 µg/lane). TMPRSS2 (arrow) was detected using the purified polyclonal antibody. TMPRSS2 Antibody (N-term) (ABIN391563) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, WB   0.1 mg Log in to see 10 to 12 Days
$375.38
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lung labeled with Anti PRSS10/TMPRSS2 Polyclonal Antibody, Unconjugated (ABIN716876) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse lung labeled with Anti TMPRSS2 Polyclonal Antibody, Unconjugated  followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

TMPRSS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TMPRSS2 Antibodies

  1. Human Polyclonal TMPRSS2 Primary Antibody for EIA, WB - ABIN453423 : Gopalan, Leversha, Satagopan, Zhou, Al-Ahmadie, Fine, Eastham, Scardino, Scher, Tickoo, Reuter, Gerald: TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. in Cancer research 2009 (PubMed)
    Show all 2 references for 453423

  2. Human Polyclonal TMPRSS2 Primary Antibody for EIA, WB - ABIN453424 : Hofer, Kuefer, Maier, Herkommer, Perner, Demichelis, Paiss, Vogel, Rubin, Hoegel: Genome-wide linkage analysis of TMPRSS2-ERG fusion in familial prostate cancer. in Cancer research 2009 (PubMed)
    Show all 2 references for 453424

  3. Human Polyclonal TMPRSS2 Primary Antibody for ELISA, WB - ABIN449738 : Tomlins, Laxman, Dhanasekaran, Helgeson, Cao, Morris, Menon, Jing, Cao, Han, Yu, Wang, Montie, Rubin, Pienta, Roulston, Shah, Varambally, Mehra, Chinnaiyan: Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. in Nature 2007 (PubMed)

More Antibodies against TMPRSS2 Interaction Partners

Human Transmembrane Protease, serine 2 (TMPRSS2) interaction partners

  1. Study provide evidence that PTEN (show PTEN Antibodies) deletion and TMPRSS2-ERG (show ERG Antibodies) gene fusion were mutually exclusive in patients with prostate neoplasm. TMPRSS2-ERG (show ERG Antibodies) gene fusion was rare compared to peripheral zone tumors and to PTEN (show PTEN Antibodies) inactivation in T1a (show PDPN Antibodies) transition zone tumors.

  2. miR (show MLXIP Antibodies)-204 upregulates androgen receptor (AR (show AR Antibodies) ) and downregulates TMPRSS2/ERG (show ERG Antibodies) through direct regulation of their promoter methylation and set of transcription factors during AR cancer-related reprogramming.

  3. differential expression of TMPRSS2:ERG (show ERG Antibodies) in urine exosomes in prostate cancer and controls

  4. The present study established evidence for the first two common PrCa risk variants differentially associated with TMPRSS2:ERG (show ERG Antibodies) fusion status. TMPRSS2:ERG (show ERG Antibodies) phenotyping of larger studies is required to determine comprehensive sets of variants with subtype-specific roles in prostate cancer.

  5. Human coronavirus 229E presumably evolved to bypass the endosome by entering the cell via TMPRSS2.

  6. TMPRSS2-ERG (show ERG Antibodies) role in prostate cancer invasiveness and regulation of MMP-9 (show MMP9 Antibodies) and plexin B1 (show PLXNB1 Antibodies).

  7. Our results indicate that it is possible to predict pT3 (show ZNF135 Antibodies) stage at final histology from TMPRSS2:ERG (show ERG Antibodies) gene fusion at initial core needle biopsy. FISH determination of TMPRSS2:ERG (show ERG Antibodies) gene fusion may be particularly useful for patients scheduled to undergo a radical prostatectomy in order to improve oncological and functional results

  8. Data show there was a good agreement of transcriptional regulator ERG (show ERG Antibodies) protein (ERG (show ERG Antibodies)) immunostaining with the presence of TMPRSS2:ERG (show ERG Antibodies) fusion protein.

  9. A combination of high preoperative serum PSA (show PLAG1 Antibodies) and high expression of TMPRSS2-ERG (show ERG Antibodies) could be promising in distinguishing those tumors that are aggressive and life-threatening.

  10. Studies showed that urinary TMPRSS2:ERG (show ERG Antibodies) transcripts seem to be indicative of Prostate cancer aggressiveness upon biopsy. [review]

Mouse (Murine) Transmembrane Protease, serine 2 (TMPRSS2) interaction partners

  1. DPP4 (show DPP4 Antibodies):CD9 (show CD9 Antibodies):TTSP (show TMPRSS11E Antibodies) as the protein complexes are necessary for early efficient MERS-coronavirus entry.

  2. Genetic inhibition of TMPRSS2-ERG (show ERG Antibodies) junction oncogene (show RAB1A Antibodies) in prostate cancer by means of siRNA has strong antineoplastic effect in a mouse model and in vitro.

  3. The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis

  4. TMPRSS2 as a host cell factor essential for viral spread and pathogenesis of mono-basic H1N1 and H3N2 influenza A viruses.

  5. These results demonstrate that TMPRSS2 expression is essential for influenza A virus replication in vivo.

  6. These data demonstrate that TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 and H1N1 influenza virus in mice.

  7. Loss of TMPRSS2 serine protease (show F2 Antibodies) activity does not influence fertility, reduce survival, result in prostate hyperplasia or carcinoma, or alter prostatic luminal epithelial cell regrowth following castration and androgen replacement.

TMPRSS2 Antigen Profile

Protein Summary

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TMPRSS2

  • transmembrane protease serine 2-like (LOC100739411) antibody
  • transmembrane protease, serine 2 (TMPRSS2) antibody
  • transmembrane protease, serine 2 (Tmprss2) antibody
  • transmembrane protease, serine 2-like (LOC100337870) antibody
  • D16Ertd61e antibody
  • PP9284 antibody
  • PRSS10 antibody

Protein level used designations for TMPRSS2

epitheliasin , serine protease 10 , transmembrane protease serine 2 , plasmic transmembrane protein X

GENE ID SPECIES
100739411 Sus scrofa
7113 Homo sapiens
156435 Rattus norvegicus
50528 Mus musculus
418528 Gallus gallus
100732077 Cavia porcellus
100337870 Oryctolagus cuniculus
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