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Transmembrane Protein 173 (TMEM173) ELISA Kits

Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Additionally we are shipping TMEM173 Antibodies (132) and TMEM173 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human TMEM173 TMEM173 340061 Q86WV6
TMEM173 72512 Q3TBT3
Anti-Rat TMEM173 TMEM173 498840  
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Top TMEM173 ELISA Kits at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Chicken 7.8 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 11 to 13 Days
$1,026.67
Details
Mouse 3.9 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Human 0.062 ng/mL 0.15-10 ng/mL   96 Tests Log in to see 9 to 11 Days
$941.11
Details

More ELISA Kits for TMEM173 Interaction Partners

Human Transmembrane Protein 173 (TMEM173) interaction partners

  1. The study demonstrates the lack of association between the presence of systemic autoimmune diseases and mutations in exon 5 of the TMEM173 gene.

  2. cGAS and STING are intracellular sensors that activate the interferon (show IFNA ELISA Kits) pathway in response to virus infection. [review]

  3. Studies suggest that the transmembrane protein 173 (STING) pathway is the main innate immune pathway involved in sensing of tumors, and its endogenous activation in APCs (show APCS ELISA Kits) leads to subsequent T cell priming against tumor-associated antigens.

  4. A STING-dependent, cGAS-independent pathway important for full interferon (show IFNA ELISA Kits) production and antiviral control of enveloped RNA viruses.

  5. Studies indicate that the STING (stimulator of interferon (show IFNA ELISA Kits) genes)-controlled innate immune pathway has provided insight for treating autoinflammatory disease and cancer.

  6. This study demonstrates that E2 proteins of high risk human papillomavirus reduce STING and IFN-kappa transcription.

  7. Results reveal a critical role of STING in regulating dsDNA-triggered activation of the JAK1 (show JAK1 ELISA Kits)-STAT1 (show STAT1 ELISA Kits) signaling in B cells and highlight the close associations of STING low-expression with JAK1 (show JAK1 ELISA Kits)-STAT1 (show STAT1 ELISA Kits) signaling in systemic lupus erythematosus B cells.

  8. Data identifies a single amino acid change in STING that leads to its constitutive activation of downstream signaling, by increasing its propensity to dimerize and associate with TBK1 (show TBK1 ELISA Kits).

  9. findings demonstrate a novel regulatory circuit in which STING and TBK1 (show TBK1 ELISA Kits) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A (show PPM1A ELISA Kits) dephosphorylates STING and TBK1 (show TBK1 ELISA Kits)

  10. STING(sv) inhibited the activity of the interferon (show IFNA ELISA Kits) (IFN)-beta (show IFNB1 ELISA Kits) promoter.

Mouse (Murine) Transmembrane Protein 173 (TMEM173) interaction partners

  1. NLRX1 (show NLRX1 ELISA Kits) sequesters the DNA-sensing adaptor STING from interaction with TBK1 (show TBK1 ELISA Kits), which is a requisite for IFN-1 induction in response to viral DNA.

  2. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1 (show RPS6KB1 ELISA Kits))-STING membrane protein-TANK-binding kinase 1 (TBK1 (show TBK1 ELISA Kits)) complex was necessary for the activation of interferon regulatory factor-3 (IRF3 (show IRF3 ELISA Kits)).

  3. Sting protein role in the innate immune response and interferon (show IFNA ELISA Kits)-stimulated genes response pathway

  4. required for chitosan-mediated enhancement of antigen specific Th1 (show HAND1 ELISA Kits) and immunoglobulin G2 responses following vaccination

  5. in vitro activation of the AIM2 (show AIM2 ELISA Kits) inflammasome in murine macrophages and dendritic cells leads to reduced activation of the STING pathway, in part through promoting caspase-1 (show CASP1 ELISA Kits)-dependent cell death.

  6. A STING-dependent, cGAS-independent pathway important for full interferon (show IFNA ELISA Kits) production and antiviral control of enveloped RNA viruses.

  7. the G37S mutation of RNaseH2 led to increased expression of interferon (show IFNA ELISA Kits)-stimulated genes dependent on the cGAS-STING signaling pathway.

  8. enforced activation of STING by intratumoral injection of cyclic dinucleotide GMP (show NT5C2 ELISA Kits)-AMP (show TMPRSS5 ELISA Kits) (cGAMP), potently enhanced antitumor CD8 (show CD8A ELISA Kits) T responses.

  9. Results reveal a critical role of STING in regulating dsDNA-triggered activation of the JAK1 (show JAK1 ELISA Kits)-STAT1 (show STAT1 ELISA Kits) signaling in B cells and highlight the close associations of STING low-expression with JAK1 (show JAK1 ELISA Kits)-STAT1 (show STAT1 ELISA Kits) signaling in systemic lupus erythematosus B cells.

  10. findings demonstrate a novel regulatory circuit in which STING and TBK1 (show TBK1 ELISA Kits) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A (show PPM1A ELISA Kits) dephosphorylates STING and TBK1 (show TBK1 ELISA Kits)

Pig (Porcine) Transmembrane Protein 173 (TMEM173) interaction partners

TMEM173 Antigen Profile

Antigen Summary

Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double- stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti- viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

Gene names and symbols associated with TMEM173

  • transmembrane protein 173 (TMEM173) antibody
  • transmembrane protein 173 (Tmem173) antibody
  • 2610307O08Rik antibody
  • ERIS antibody
  • Mita antibody
  • MPYS antibody
  • NET23 antibody
  • RGD1562552 antibody
  • STING antibody

Protein level used designations for TMEM173

transmembrane protein 173 , N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner , endoplasmic reticulum IFN stimulator , endoplasmic reticulum interferon stimulator , hMITA , hSTING , mediator of IRF3 activation , mitochondrial mediator of IRF3 activation , stimulator of interferon genes protein , MMITA , mSTING , Stimulator of interferon genes protein , mitochondrial transmembrane protein 173

GENE ID SPECIES
606815 Canis lupus familiaris
462107 Pan troglodytes
694353 Macaca mulatta
100459760 Pongo abelii
340061 Homo sapiens
72512 Mus musculus
533661 Bos taurus
768990 Gallus gallus
100217389 Sus scrofa
498840 Rattus norvegicus
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