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Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope.
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Cow (Bovine) Polyclonal TMEM48 Primary Antibody for WB - ABIN2773878
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
Show all 2 references for ABIN2773878
The interaction between Nup53 and the integral pore membrane protein Ndc1 is essential for vertebrate nuclear pore complex assembly.
ELYS chromatin capture recruits POM121 and NDC1 to initiate nuclear pore assembly
Human homologue NDC1/NET3 contains three FG repeats in the C-terminus, a feature of many nuclear pore proteins.
NDC1-mediated localization of ALADIN to nuclear pore complexes is essential for selective nuclear protein import; abrogation of the interaction between ALADIN and NDC1 may be important for the development of triple-A syndrome.
ALADIN (show AAAS Antibodies) is anchored in the nuclear envelope via NDC1 and that this interaction gets lost, if ALADIN (show AAAS Antibodies) is mutated.
A mutation in the nuclear pore complex gene Tmem48 causes gametogenesis defects in skeletal fusions with sterility (sks) mice.
Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
, transmembrane protein 48
, nuclear division cycle 1 homolog