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Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains 2 Proteins (TMEFF2)

May be a survival factor for hippocampal and mesencephalic neurons. Additionally we are shipping TMEFF2 Antibodies (82) and TMEFF2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TMEFF2 23671 Q9UIK5
TMEFF2 56363 Q9QYM9
Rat TMEFF2 TMEFF2 363228  
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Top TMEFF2 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,737.17
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$704.00
Details

TMEFF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine) ,
,

More Proteins for Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains 2 (TMEFF2) Interaction Partners

Human Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains 2 (TMEFF2) interaction partners

  1. Results suggest that TMEFF2 is a brain-enriched endogenous modulator of Abeta (show APP Proteins) neurotoxicity and an enhancer of alpha-secretase processing of AbetaPP

  2. TMEFF2 regulates the non-canonical activin/BMP4 signaling, PI3K, and Ras/ERK1/2 pathways.

  3. c-Myc (show MYC Proteins) contributes to the epigenetic regulation of HPP1 (show NAE1 Proteins) via the dominant recruitment of HDAC3 (show HDAC3 Proteins).

  4. TMEFF2 acts as a tumor suppressor in gastric cancer through direct interaction with SHP-1 and can be a potential biomarker of carcinogenesis.

  5. TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells.

  6. Androgen signaling promotes eIF2alpha (show EIF2A Proteins) phosphorylation and subsequent translation of TMEFF2 via a mechanism that requires uORFs in the 5'-UTR of TMEFF2.

  7. Methylation of TMEFF2 gene is associated with colorectal neoplasia in ulcerative colitis and Crohn's colitis.

  8. Findings suggest that methylation-associated down-regulation of TMEFF2 gene may be involved in lung tumorigenesis and TMEFF2 methylation can serve as a specific blood-based biomarker for NSCLC.

  9. Several genes expressed at exceptionally high levels were identified associated with early oocyte development, TMEFF2, the Rho-GTPase-activating protein oligophrenin 1 (OPHN1) and the mitochondrial-encoded ATPase6 (ATP6).

  10. TMEFF2 can function to regulate PDGF (show PDGFA Proteins) signaling; it is hypermethylated and downregulated in glioma and several other cancers

Mouse (Murine) Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains 2 (TMEFF2) interaction partners

  1. Results suggest that TMEFF2 is a brain-enriched endogenous modulator of Abeta (show APP Proteins) neurotoxicity and an enhancer of alpha-secretase processing of AbetaPP

  2. Loss of TMEFF2 is associated with cell migration and invasion leading to prostate cancer.

TMEFF2 Protein Profile

Protein Summary

May be a survival factor for hippocampal and mesencephalic neurons. The shedded form may up-regulate cell proliferation (By similarity).

Gene names and symbols associated with TMEFF2

  • transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2)
  • novel protein similar to vertebrate transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) (DKEY-9G20.2)
  • transmembrane protein with EGF-like and two follistatin-like domains 2 (LOC100345498)
  • transmembrane protein with EGF-like and two follistatin-like domains 2 (Tmeff2)
  • 4832418D20Rik protein
  • 7630402F16Rik protein
  • CT120.2 protein
  • HPP1 protein
  • LOC100004613 protein
  • TENB2 protein
  • TPEF protein
  • TR protein

Protein level used designations for TMEFF2

transmembrane protein with EGF-like and two follistatin-like domains 2 , TR-2 , cancer/testis antigen family 120, member 2 , hyperplastic polyposis protein 1 , tomoregulin , tomoregulin-2 , transmembrane protein TENB2

GENE ID SPECIES
100054833 Equus caballus
100004613 Danio rerio
100345498 Oryctolagus cuniculus
23671 Homo sapiens
56363 Mus musculus
768542 Gallus gallus
478848 Canis lupus familiaris
654831 Sus scrofa
538354 Bos taurus
363228 Rattus norvegicus
100714257 Cavia porcellus
Selected quality suppliers for TMEFF2 Proteins (TMEFF2)
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