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anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) Antibodies

The membrane-associated protein encoded by TAP1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) Kits (28) and Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TAP1 6890 Q03518
TAP1 21354 P21958
TAP1 24811  
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Top anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) Antibodies at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-TAP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1... Host: Rabbit  Target Name: TAP1  Sample Tissue: Hela  Antibody Dilutio... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with ... TAP1 Antibody (I795) (ABIN390185) western blot analysis in Jurkat cell... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse FITC FACS 50 μg Log in to see 6 to 8 Days
$346.50
Details
Human Mouse Un-conjugated ICC, IF, IP, ELISA, WB 50 μL Log in to see 5 to 6 Days
$429.10
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- TAP1 Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer T... 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated FACS, IP, WB 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

TAP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, ,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) Antibodies

  1. Human Polyclonal TAP1 Primary Antibody for IHC (p), WB - ABIN390185 : Lajoie, Zijenah, Faucher, Ward, Roger: Novel TAP1 polymorphisms in indigenous Zimbabweans: their potential implications on TAP function and in human diseases. in Human immunology 2003 (PubMed)
    Show all 5 references for ABIN390185

  2. Human Polyclonal TAP1 Primary Antibody for EIA, IHC (p) - ABIN1449427 : Gaudet, Wiley: Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing. in The EMBO journal 2001 (PubMed)
    Show all 5 references for ABIN1449427

  3. Human Monoclonal TAP1 Primary Antibody for ICC, IF - ABIN108594 : Kim, Kataoka, Dreyfuss: Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex. in Science (New York, N.Y.) 2001 (PubMed)

  4. Chicken Polyclonal TAP1 Primary Antibody for WB - ABIN2781498 : Soundravally, Hoti: Polymorphisms of the TAP 1 and 2 gene may influence clinical outcome of primary dengue viral infection. in Scandinavian journal of immunology 2008 (PubMed)

  5. Human Polyclonal TAP1 Primary Antibody for IF (cc), IF (p) - ABIN680728 : Stettner, Lohmann, Wolffram, Weinberger, Dehmel, Hartung, Mausberg, Kieseier: Interleukin-17 impedes Schwann cell-mediated myelination. in Journal of neuroinflammation 2014 (PubMed)

More Antibodies against Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) Interaction Partners

Human Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) interaction partners

  1. IFNalpha upregulates TAP1 expression in peripheral blood mononuclear cells (PBMCs) of patients with malignant melanoma receiving adjuvant high-dose immunotherapy.

  2. PSF1 expression correlates with a more aggressive phenotype as well as worse prognosis in hepatocellular carcinoma patients.

  3. PSF1 is expressed in high-grade prostate cancer and may be a useful biomarker to identify patients with a poor prognosis at the time of diagnosis

  4. Studies indicate that ABC (show ABCB6 Antibodies) transporters associated with antigen processing TAP1/2 (ABCB2/3) is a crucial element of the adaptive immune system.

  5. None of TAP1 alleles showed a signi fi cant di ff erence in phenotype frequency between pulmonary tuberculosis and controls, and among subgroups of pulmonary tuberculosis.

  6. The TAP1-rs1135216 and PSMB9 (show PSMB9 Antibodies)-rs17587 variants are significantly associated with vitiligo (show MITF Antibodies), and even one copy of these mutant alleles can influence the risk among Saudis.

  7. PSF1 was overexpressed in lung cancer.

  8. TAP1 I333V gene polymorphism was significantly associated with increased type 1 diabetes mellitus risk.

  9. Participants with a mutated allele had an increased risk for CRC (show CALR Antibodies). The adjusted odds ratios for the C/T, T/T, and the mutation type (C/T + T/T) compared to that of wild type (C/C) were 2.27, 1.95, and 2.22 respectively.

  10. Results suggested an association of TAP1-333 polymorphism with multiple myeloma.

Mouse (Murine) Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) interaction partners

  1. It transport class I antigens to cell surface of CD8 (show CD8A Antibodies) positive lymphocytes which have a vital role in liver inflammation like fructose-induced steatosis.

  2. Knocking out Tap1 abolishes NMDAR-dependent LTD in area CA1 of adult mouse hippocampus and is accompanied by memory deficits. MHC class I expression could be an unexpected cause of disrupted synaptic plasticity and cognitive deficits.

  3. Apoe (show APOE Antibodies)(-/-)Tap1(-/-) mice develop atherosclerosis equal to Apoe (show APOE Antibodies)(-/-) mice, indicating a minor role for CD8 (show CD8A Antibodies)(+) T cells and TAP1-dependent antigen presentation in the disease process.

  4. Role of metalloproteases in vaccinia virus epitope processing for transporter associated with antigen processing (TAP)-independent human leukocyte antigen (show HLADRB4 Antibodies) (HLA)-B7 class I antigen presentation.

  5. A complete overview is presented of the applicability of herpesvirus-encoded TAP and tapasin (show TAPBP Antibodies) inhibitors in mouse cells of different genetic background.

  6. Our results do not support a role for MHC class I (TAP1) in adult neurogenesis, although it may still have a role in the maturation and integration of newborn neurons.

  7. a new role for mouse TAP2 in stabilizing TAP1 protein expression is shown using the Jasmine strain; Jasmine has an A to C transversion in exon 5 of TAP2, resulting in a threonine to proline substitution at position 293 of the protein.

  8. Allergen-specific CD8 (show CD8A Antibodies)+ T cells were recruited to and specifically activated in the lungs of sensitized animals after allergen-aerosol challenge, a process that was dependent on a functional TAP complex

  9. MHC conformational changes, revealed at molecular level, may influence the immunogenicity

  10. Macrophages cross-presented p33 (show LTB Antibodies)-VLP (show VHLL Antibodies) normally in the absence of TAP. The TAP-dependent pathway of cross-presentation is therefore confined to DC while both macrophages and DC harbor the TAP-independent pathway.

Pig (Porcine) Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) interaction partners

  1. data indicate that TAP1 expression is increased by demethylation of promoter CpG islands, with CpG_4, CpG_13 and CpG_15 implicated as the critical regulatory sites

  2. The TAP1 mRNA levels in GG genotype were significantly higher than that in the other two genotypes, with significant differences in the liver, lung, kidney, thymus, lymph node, duodenum and jejunum tissues.

  3. These analyses showed that the TAP1 gene, which was related to MHC I immune regulation, had a stable and low expression level in unweaned stages; however, its expression increased in the postweaning stages.

  4. The TAP1 gene is associated with swine immune responses.

  5. Two splice variants of TAP1 were found.

Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.

Gene names and symbols associated with TAP1

  • transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (TAP1) antibody
  • transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (tap1) antibody
  • transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1) antibody
  • abc17 antibody
  • Abcb2 antibody
  • apt1 antibody
  • Cim antibody
  • D6S114E antibody
  • Ham-1 antibody
  • Ham1 antibody
  • MTP1 antibody
  • PSF-1 antibody
  • psf1 antibody
  • ring4 antibody
  • TAP antibody
  • Tap-1 antibody
  • TAP1*0102N antibody
  • tap1a antibody
  • tap1n antibody
  • Y3 antibody

Protein level used designations for TAP1

ABC transporter, MHC 1 , ATP-binding cassette sub-family B member 2 , ATP-binding cassette, sub-family B (MDR/TAP), member 2 , antigen peptide transporter 1 , peptide supply factor 1 , peptide transporter PSF1 , peptide transporter TAP1 , peptide transporter involved in antigen processing 1 , really interesting new gene 4 protein , transporter associated with antigen processing , transporter, ATP-binding cassette, major histocompatibility complex, 1 , transporter associated with antigen processing 1a , transporter associated with antigen presentation 1 , transporter associated with antigen processing 1 , transporter 1 ATP-binding cassette sub-family B , ABC transporter, MHC, 1 , ATP dependent transport protein family member , ATP-binding cassette transporter, major histocompatibility complex, 1 , histocompatibility antigen modifier 1 , transporter 1, ABC (ATP binding cassette) , transporter, ABC, MHC, 1 , APT1 , transporter 1 ABC (ATP binding cassette)

GENE ID SPECIES
6890 Homo sapiens
100329838 Xenopus laevis
427727 Gallus gallus
524959 Bos taurus
21354 Mus musculus
24811 Rattus norvegicus
733649 Sus scrofa
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