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Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) Proteins (TAP2)

The membrane-associated protein encoded by TAP2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping TAP2 Antibodies (74) and TAP2 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TAP2 6891 Q03519
TAP2 21355 P36371
Rat TAP2 TAP2 24812 P36372
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Top TAP2 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

TAP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine) ,
,

More Proteins for Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) Interaction Partners

Human Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) interaction partners

  1. TAP/TPN complex formation is driven by hydrophobic interactions via leucine zipper-like motifs.

  2. TAP2, HLA-DOA (show HLA-DOA Proteins), HLA-DOB (show HLA-DOB Proteins), and tapasin (show TAPBP Proteins) loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  3. Studies indicate that ABC (show ABCB6 Proteins) transporters associated with antigen processing TAP1 (show TAP1 Proteins)/2 (ABCB2 (show TAP1 Proteins)/3) is a crucial element of the adaptive immune system.

  4. We showed that TAP2 gene has an association with pulmonary tuberculosis in Koreans.

  5. Our meta-analyses suggested that TAP2-379Ile allele was significantly associated with a 59% increased risk for rheumatoid arthritis

  6. Results suggested an association between TAP2-565 polymorphism and chronic lymphoid leukemia (CLL). TAP2-665 GG genotype might be a risk factor for CLL, chronic myeloblastic leukemia, and multiple myeloma.

  7. TAP1 AND TAP2 polymorphisms are associated with a reduced risk for developing cervical intraepithelial neoplasia.

  8. Three tapasin binding sites on TAP have been described, two of which are located in the N-terminal domains of TAP1 and TAP2.

  9. TAP1-TAP2 NBD dimers are not fully stabilized by nucleotides alone, and substrate binding plays a key role in inducing the transition state conformations of the NBD.

  10. the N-terminal region of Snm1B (show DCLRE1B Proteins) forms a complex containing PSF2 and Mus81 (show MUS81 Proteins), while the C-terminal region is important for PSF2-mediated chromatin association.

Mouse (Murine) Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) interaction partners

  1. The Rose strain has an A to T substitution in exon 10 of TAP1 (show TAP1 Proteins), resulting in an asparagine to valine substitution at position 643; defective TAP expression mice have very low major histocompatibility complex-I cell-surface expression, and few CD8 (show CD8A Proteins) T cells.

  2. A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression

TAP2 Protein Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.

Gene names and symbols associated with TAP2

  • transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2)
  • transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (Tap2)
  • ABC18 protein
  • Abcb3 protein
  • AI462429 protein
  • APT2 protein
  • Cim protein
  • D6S217E protein
  • Ham-2 protein
  • Ham2 protein
  • jas protein
  • MTP2 protein
  • PSF-2 protein
  • PSF2 protein
  • RING11 protein
  • Tap-2 protein
  • Y1 protein

Protein level used designations for TAP2

ABC transporter, MHC 2 , ATP-binding cassette, sub-family B (MDR/TAP), member 3 , antigen peptide transporter 2 , peptide supply factor 2 , peptide transporter PSF2 , peptide transporter involved in antigen processing 2 , really interesting new gene 11 protein , transporter 2, ABC (ATP binding cassette) , ATP dependent transport protein family member , ATP-binding cassette sub-family B member 3 , histocompatibility antigen modifier 2 , APT2 , Transporter 2 ABC (ATP binding cassette) , ABC-transporter , transporter 2, ABC(ATP binding cassette) , transporter 2, ATP-binding cassette, sub-family B

GENE ID SPECIES
6891 Homo sapiens
21355 Mus musculus
24812 Rattus norvegicus
281586 Bos taurus
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