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Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Additionally we are shipping TFF3 Kits (81) and TFF3 Proteins (42) and many more products for this protein.
Showing 10 out of 143 products:
Human Monoclonal TFF3 Primary Antibody for IHC (p), ELISA - ABIN563166
Bignotti, Ravaggi, Tassi, Calza, Rossi, Falchetti, Romani, Bandiera, Odicino, Pecorelli, Santin: Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomas. in British journal of cancer 2008
Show all 7 references for ABIN563166
Human Polyclonal TFF3 Primary Antibody for IF (p), IHC (p) - ABIN669786
Kimura, van der Merwe, Bering, Penmatsa, Conoley, Sangild, Naren, Buddington: Glucose transport by epithelia prepared from harvested enterocytes. in Cytotechnology 2015
Human Polyclonal TFF3 Primary Antibody for EIA, WB - ABIN783349
Zhao, Li, Pan, Liu, Lv, Leung, Lu: Enhanced gene delivery by chitosan-disulfide-conjugated LMW-PEI for facilitating osteogenic differentiation. in Acta biomaterialia 2013
Human Monoclonal TFF3 Primary Antibody for ELISA, WB - ABIN563167
Hamady, Farrar, Whitehead, Holland, Lodge, Carding: Identification and use of the putative Bacteroides ovatus xylanase promoter for the inducible production of recombinant human proteins. in Microbiology (Reading, England) 2008
Human Polyclonal TFF3 Primary Antibody for IHC, ELISA - ABIN1585377
Borniquel, Jädert, Lundberg: Dietary conjugated linoleic acid activates PPARγ and the intestinal trefoil factor in SW480 cells and mice with dextran sulfate sodium-induced colitis. in The Journal of nutrition 2012
TFF3 protein knockout can facilitate apoptosis of human pituitary adenoma HP75 cells via mitochondrial pathway
Data show that trefoil factor-3 (TFF3) secreted from mammary carcinoma cells promotes de novo angiogenesis via interleukin-8 (IL-8 (show IL8 Antibodies))/IL-8 (show IL8 Antibodies) receptor (show CXCR1 Antibodies) CXCR2 (show CXCR2 Antibodies).
Dimers CXCR4 (show CXCR4 Antibodies) and CXCR7 (show CXCR7 Antibodies) are involved in TFF3-dependent activation of cell migration, but not cell proliferation. The ERK1/2 (show MAPK1/3 Antibodies) pathway is activated in the process, but not influenced by CXCR4 (show CXCR4 Antibodies) or CXCR7 (show CXCR7 Antibodies).
These findings suggest that the rs184432 and rs225359 polymorphisms in TFF1 (show TFF1 Antibodies) have protective effects for GC and contribute to the development of GC in Korean individuals.
TFF3 expression is associated with response to endocrine therapy, and outperforms oestrogen receptor, progesterone receptor (show PGR Antibodies) and TFF1 (show TFF1 Antibodies) as an independent biomarker, possibly because it mediates the malign effects of oestrogen on invasion and metastasis
the results provide a mechanistic explanation for ITF-mediated protection of gastric epithelial mucosa cells, suggesting that activation of the ERK1/2 (show MAPK1/3 Antibodies) signaling pathway may provide a new therapeutic strategy for repairing gastric injury.
primary outcome measures were to evaluate the safety, acceptability, and accuracy of the Cytosponge-TFF3 test compared with endoscopy and biopsy. In all, 1,042 (93.9%) patients successfully swallowed the Cytosponge, and there were no serious side effects
TFF3 is not only a useful biomarker for a long-term surgical result in CRC (show CALR Antibodies) patient, but also may be a risk factor of early recurrence.
Associations discovered between trefoil factor 3 gene variants and idiopathic recurrent spontaneous abortion.
TFF3 expression predicts metastasis and poor survival outcome of patients with mammary carcinoma.
TFF3 is regulated by food intake, improves glucose tolerance and induces mucinous metaplasia.
TFF1 (show TFF1 Antibodies) and TFF3 peptides might be involved in the complex processes of nervous system development and differentiation and brain plasticity.
The TFF3 was present in cartilage chondrocytes undergoing endochondral ossification, particularly in zone of proliferation, hypertrophy and calcification as well as in zone of cartilage degeneration during the monitored fetal period.
Intravenous administration of recombinant TFF3 reversed changes in cerebral injury.
Tff3 peptides are involved in glucose homeostasis and insulin (show INS Antibodies) sensitivity, providing a promising peptide on new therapies against the metabolic disorders associated with type 2 diabetes mellitus.
The genetically deleting Tff3 in mice altered down-regulated Pttg1 and up-regulated serpina3n expression, indicating a potential role of these factors during the development of presbyacusis.
Tff3 knock out mice have lower body weight than wild-type mice.
Soy protein diet, but not Lactobacillus rhamnosus GG, decreases mucin-1 (show MUC1 Antibodies), trefoil factor-3, and tumor necrosis factor-alpha (show TNF Antibodies) in colon of dextran sodium sulfate-induced colitis.
results suggest that a diminution of the intestinal trefoil factor system may be involved in the acceleration of aging in SAM (show TTN Antibodies)-P6 mice
Loss of the barrier protective molecule TFF3 leads to a profound increase in susceptibility to DSS (show PMP22 Antibodies)-induced colitis, and this can be abrogated by reducing Fuc-TVII (show FUT7 Antibodies)-dependent leukocyte recruitment.
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
trefoil factor 3 (intestinal)
, polypeptide P1.B
, trefoil factor 3
, intestinal trefoil factor
, Intestinal trefoil factor
, trefoil factor family peptide 3