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Trefoil Factor 3 (Intestinal) Proteins (TFF3)

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Additionally we are shipping TFF3 Antibodies (145) and TFF3 Kits (81) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TFF3 7033 Q07654
TFF3 21786 Q62395
TFF3 25563 Q03191
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Top TFF3 Proteins at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$750.20
Details
HOST_Escherichia coli (E. coli) Mouse His tag,MBP tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Escherichia coli (E. coli) Wild boar His tag,MBP tag 100 μg Log in to see 11 to 13 Days
$855.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$651.00
Details
HOST_Escherichia coli (E. coli) Dog His tag 100 μg Log in to see 11 to 13 Days
$668.80
Details

TFF3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)
,
Rat (Rattus)

Top referenced TFF3 Proteins

  1. Human TFF3 Protein expressed in Wheat germ - ABIN1322573 : Liu, Tefft, Roberts, Zhang, Ren, Li, Huang, Zhang, Phillips, Wu: Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia. in American journal of physiology. Heart and circulatory physiology 2012 (PubMed)
    Show all 5 references for ABIN1322573

More Proteins for Trefoil Factor 3 (Intestinal) (TFF3) Interaction Partners

Human Trefoil Factor 3 (Intestinal) (TFF3) interaction partners

  1. TFF3 protein knockout can facilitate apoptosis of human pituitary adenoma HP75 cells via mitochondrial pathway

  2. Data show that trefoil factor-3 (TFF3) secreted from mammary carcinoma cells promotes de novo angiogenesis via interleukin-8 (IL-8 (show IL8 Proteins))/IL-8 (show IL8 Proteins) receptor (show CXCR1 Proteins) CXCR2 (show CXCR2 Proteins).

  3. Dimers CXCR4 and CXCR7 are involved in TFF3-dependent activation of cell migration, but not cell proliferation. The ERK1/2 pathway is activated in the process, but not influenced by CXCR4 or CXCR7.

  4. These findings suggest that the rs184432 and rs225359 polymorphisms in TFF1 (show TFF1 Proteins) have protective effects for GC and contribute to the development of GC in Korean individuals.

  5. TFF3 expression is associated with response to endocrine therapy, and outperforms oestrogen receptor, progesterone receptor (show PGR Proteins) and TFF1 (show TFF1 Proteins) as an independent biomarker, possibly because it mediates the malign effects of oestrogen on invasion and metastasis

  6. the results provide a mechanistic explanation for ITF-mediated protection of gastric epithelial mucosa cells, suggesting that activation of the ERK1/2 signaling pathway may provide a new therapeutic strategy for repairing gastric injury.

  7. primary outcome measures were to evaluate the safety, acceptability, and accuracy of the Cytosponge-TFF3 test compared with endoscopy and biopsy. In all, 1,042 (93.9%) patients successfully swallowed the Cytosponge, and there were no serious side effects

  8. TFF3 is not only a useful biomarker for a long-term surgical result in CRC (show CALR Proteins) patient, but also may be a risk factor of early recurrence.

  9. Associations discovered between trefoil factor 3 gene variants and idiopathic recurrent spontaneous abortion.

  10. TFF3 expression predicts metastasis and poor survival outcome of patients with mammary carcinoma.

Mouse (Murine) Trefoil Factor 3 (Intestinal) (TFF3) interaction partners

  1. TFF3 is regulated by food intake, improves glucose tolerance and induces mucinous metaplasia.

  2. TFF1 (show TFF1 Proteins) and TFF3 peptides might be involved in the complex processes of nervous system development and differentiation and brain plasticity.

  3. The TFF3 was present in cartilage chondrocytes undergoing endochondral ossification, particularly in zone of proliferation, hypertrophy and calcification as well as in zone of cartilage degeneration during the monitored fetal period.

  4. Intravenous administration of recombinant TFF3 reversed changes in cerebral injury.

  5. Tff3 peptides are involved in glucose homeostasis and insulin (show INS Proteins) sensitivity, providing a promising peptide on new therapies against the metabolic disorders associated with type 2 diabetes mellitus.

  6. The genetically deleting Tff3 in mice altered down-regulated Pttg1 (show PTTG1 Proteins) and up-regulated serpina3n (show SERPINA3N Proteins) expression, indicating a potential role of these factors during the development of presbyacusis.

  7. Tff3 knock out mice have lower body weight than wild-type mice.

  8. Soy protein diet, but not Lactobacillus rhamnosus GG, decreases mucin-1 (show MUC1 Proteins), trefoil factor-3, and tumor necrosis factor-alpha (show TNF Proteins) in colon of dextran sodium sulfate-induced colitis.

  9. results suggest that a diminution of the intestinal trefoil factor system may be involved in the acceleration of aging in SAM (show TTN Proteins)-P6 mice

  10. Loss of the barrier protective molecule TFF3 leads to a profound increase in susceptibility to DSS (show PMP22 Proteins)-induced colitis, and this can be abrogated by reducing Fuc-TVII (show FUT7 Proteins)-dependent leukocyte recruitment.

TFF3 Protein Profile

Protein Summary

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Gene names and symbols associated with TFF3

  • trefoil factor 3 (intestinal) (TFF3)
  • trefoil factor 3 (intestinal) (Tff3)
  • trefoil factor 3-like (LOC100739705)
  • trefoil factor 3, intestinal (Tff3)
  • ITF protein
  • mITF protein
  • P1B protein
  • TFF3 protein
  • TFI protein

Protein level used designations for TFF3

trefoil factor 3 (intestinal) , polypeptide P1.B , trefoil factor 3 , intestinal trefoil factor , Intestinal trefoil factor , trefoil factor family peptide 3

GENE ID SPECIES
474124 Pan troglodytes
7033 Homo sapiens
100732911 Cavia porcellus
517889 Bos taurus
100627480 Sus scrofa
100170655 Felis catus
403488 Canis lupus familiaris
780497 Ovis aries
100739705 Sus scrofa
21786 Mus musculus
25563 Rattus norvegicus
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