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Tribbles Homolog 1 (Drosophila) Proteins (TRIB1)

a nuclear factor\; gene expression induced by m1-acetylcholine receptor [RGD, Feb 2006].. Additionally we are shipping TRIB1 Antibodies (92) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRIB1 10221 Q96RU8
TRIB1 211770 Q8K4K4
Rat TRIB1 TRIB1 78969  
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Top TRIB1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TRIB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

More Proteins for Tribbles Homolog 1 (Drosophila) (TRIB1) Interaction Partners

Human Tribbles Homolog 1 (Drosophila) (TRIB1) interaction partners

  1. Trib1 formed a complex with pHDAC1.

  2. Studies indicate that tribbles homolog 1 (Drosophila) protein appear to be involved in some of the most common diseases, such as cancer, metabolic disease and hyperlipidaemia.

  3. Studies suggest that pseudo-kinase family of tribbles (TRIB) proteins TRIB1, TRIB2 (show TRIB2 Proteins) and TRIB3 (show TRIB3 Proteins) play roles in pathogenesis of rheumatoid arthritis (RA) and osteoarthritis.

  4. Studies indicate that the minor allele of a single nucleotide polymorphism (SNP, rs6982502) in the regulatory sequence reduces the activity of the tribbles homolog 1 (Drosophila) protein (TRIB1) promoter.

  5. Studies suggest that pseudo-kinase family of tribbles (TRIB) proteins TRIB1, TRIB2 (show TRIB2 Proteins) and TRIB3 (show TRIB3 Proteins) were involved in the pathogenesis of inflammation.

  6. Studies indicate that tribbles homolog 1 (Drosophila) protein (TRIB1) interacts with the master molecule of Tregs, forkhead box P3 (FOXP3 (show FOXP3 Proteins)), a transcription factor essential for Treg suppressive activity.

  7. Studies indicate that tribbles homolog 1 (Drosophila) protein (tribbles-1; TRIB1) is an important modulator of human energy metabolism and metabolic syndromes.

  8. Studies indicate that small molecules can reveal rate-limiting signalling outputs and functions of pseudo-kinase family of tribbles (TRIB) proteins TRIB1, TRIB2 (show TRIB2 Proteins) and TRIB3 (show TRIB3 Proteins) in cells and intact organisms, serving as guides for the development of new drugs.

  9. Studies indicate that overexpression of the wild-type tribbles homolog 1 (Drosophila) protein (Trib1) gene effectively induces leukaemia.

  10. Studies show that TRIB1 and TRIB2 (show TRIB2 Proteins) are highly expressed in molecularly-defined sub-types of acute myeloid leukemia (show BCL11A Proteins) (AML (show RUNX1 Proteins)).

Mouse (Murine) Tribbles Homolog 1 (Drosophila) (TRIB1) interaction partners

  1. The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9 (show PCSK9 Proteins)/Low Density Lipoprotein Receptor (LDLR (show LDLR Proteins)) Axis.

  2. Deletion of hepatic Trib1 leads to increased C/EBPalpha (show CEBPA Proteins) binding near upregulated lipogenic genes, as well as Trib1 itself.

  3. TRIB1 and TRIB3 (show TRIB3 Proteins) are more strongly expressed than TRIB2 (show TRIB2 Proteins) in cumulus cells (CC) surrounding oocytes from preovulatory follicles than in CC of immature ones.

  4. These data suggested that the modulation of TRIB1 expression affects hepatic lipogenesis and glycogenesis through multiple molecular interactions.

  5. In gene knock-down experiments in macrophages using small interfering RNAs targeted to Trib1, it was observed that TNF-alpha production was increased following treatment with IFN-gamma and/or TLR2 ligands.

  6. These results indicate that COP1 and Trib1 act as an oncoprotein complex functioning upstream of C/EBPalpha (show CEBPA Proteins), and its ligase activity is crucial for leukemogenesis.

  7. tribbles-1 is a novel binding partner of Foxp3 (show FOXP3 Proteins) in regulatory T cells

  8. results demonstrate that Trib1 is critical for adipose tissue maintenance and suppression of metabolic disorders by controlling the differentiation of tissue-resident M2-like macrophages

  9. Trib1-knockout mice showed elevated levels of plasma TG and cholesterol due to increased VLDL production.

  10. Trib1 transduced hematopoietic stem cells developed acute myeloid leukemia (show BCL11A Proteins).

TRIB1 Protein Profile

Protein Summary

a nuclear factor\; gene expression induced by m1-acetylcholine receptor

Gene names and symbols associated with TRIB1

  • tribbles homolog 1 (Drosophila) (TRIB1)
  • tribbles homolog 1 (Drosophila) (trib1)
  • tribbles homolog 1 (trib1)
  • tribbles homolog 1 (Drosophila) (Trib1)
  • A530090O15Rik protein
  • C8FW protein
  • Gig2 protein
  • SKIP1 protein
  • TRB-1 protein
  • Trb1 protein
  • TRIB1 protein
  • tribbles protein

Protein level used designations for TRIB1

tribbles homolog 1 (Drosophila) , G-protein-coupled receptor induced protein , phosphoprotein C8FW , tribbles homolog 1 , G-protein-coupled receptor-induced gene 2 protein , G-protein-coupled receptor-induced protein 2 , GIG-2 , TRB-1 , phosphoprotein regulated by mitogenic pathways , tribbles-like protein 1 , G-protein-coupled receptor induced protein GIG2

GENE ID SPECIES
464388 Pan troglodytes
792957 Danio rerio
100033926 Equus caballus
693459 Macaca mulatta
734240 Xenopus laevis
10221 Homo sapiens
521857 Bos taurus
211770 Mus musculus
776883 Gallus gallus
482039 Canis lupus familiaris
78969 Rattus norvegicus
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