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anti-Tribbles Homolog 2 (Drosophila) (TRIB2) Antibodies

TRIB2 encodes one of three members of the Tribbles family. Additionally we are shipping Tribbles Homolog 2 (Drosophila) Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRIB2 28951 Q92519
TRIB2 217410 Q8K4K3
TRIB2 313974  
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Top anti-Tribbles Homolog 2 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-TRIB2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB TRIB2 was detected in paraffin-embedded sections of human tonsil tissues using rabbit anti- TRIB2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method TRIB2 was detected in paraffin-embedded sections of rat spleen tissues using rabbit anti- TRIB2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to TRIB2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] TRIB2 monoclonal antibody (M04), clone 1B1 Western Blot analysis of TRIB2 expression in Jurkat (ABIN1339540). 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of TRIB2 (arrow) using rabbit polyclonal TRIB2 N-term (ABIN652876). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the TRIB2 gene (Lane 2) . TRIB2 Antibody (N-term) (ABIN652876) IHC analysis in formalin fixed and paraffin embedded mouse brain followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-TRIB2 mouse monoclonal antibody. (ABIN2452556, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-TRIB2mouse monoclonal antibody. (ABIN2452556, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000, TMB staining, Read the data in Microplate Reader by 450 nm Formalin-fixed and paraffin embedded human lung cancer labeled with Anti-TRIB2 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB Western blot analysis of TRIB2 over-expressed 293 cell line, cotransfected with TRIB2 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of TRIB2 expression in transfected 293T cell line by TRIB2 monoclonal antibody (M04), clone 1B1. Lane 1: TRIB2 transfected lysate(38.8 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Goat Un-conjugated IHC (p) Colon, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details

TRIB2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Tribbles Homolog 2 (Drosophila) Antibodies

  1. Human Monoclonal TRIB2 Primary Antibody for IHC (p), RNAi - ABIN565396 : Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ... in The Journal of biological chemistry 2013 (PubMed)
    Show all 3 references for ABIN565396

  2. Chicken Polyclonal TRIB2 Primary Antibody for WB - ABIN2786174 : Lin, Lee, Hung, Li, Yang-Yen, Yen: Survival factor withdrawal-induced apoptosis of TF-1 cells involves a TRB2-Mcl-1 axis-dependent pathway. in The Journal of biological chemistry 2007 (PubMed)

More Antibodies against Tribbles Homolog 2 (Drosophila) Interaction Partners

Xenopus laevis Tribbles Homolog 2 (Drosophila) (TRIB2) interaction partners

  1. tissues expressing the highest levels of Xtrb2 were most markedly affected by morpholino knockdown, with perturbation of neural crest and eye development

Human Tribbles Homolog 2 (Drosophila) (TRIB2) interaction partners

  1. High TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 (show TAL1 Antibodies) complex in T-cell acute lymphoblastic leukemia.

  2. Studies suggest that pseudo-kinase family of tribbles (show TRIB1 Antibodies) (TRIB) proteins TRIB1 (show TRIB1 Antibodies), TRIB2 and TRIB3 (show TRIB3 Antibodies) play roles in pathogenesis of rheumatoid arthritis (RA) and osteoarthritis.

  3. Studies suggest that pseudo-kinase family of tribbles (show TRIB1 Antibodies) (TRIB) proteins TRIB1 (show TRIB1 Antibodies), TRIB2 and TRIB3 (show TRIB3 Antibodies) were involved in the pathogenesis of inflammation.

  4. Studies suggest that tribbles homolog 2 (Drosophila) protein (TRIB2) as a meaningful biomarker to both diagnose and stage melanoma.

  5. Studies indicate that the molecular interactions that take place between tribbles homolog 2 (Drosophila) protein (TRIB2) and factors involved in the ubiquitin proteasome system (UPS) are varied and have differential downstream effects.

  6. Studies indicate that small molecules can reveal rate-limiting signalling outputs and functions of pseudo-kinase family of tribbles (show TRIB1 Antibodies) (TRIB) proteins TRIB1 (show TRIB1 Antibodies), TRIB2 and TRIB3 (show TRIB3 Antibodies) in cells and intact organisms, serving as guides for the development of new drugs.

  7. Studies show that TRIB1 (show TRIB1 Antibodies) and TRIB2 are highly expressed in molecularly-defined sub-types of acute myeloid leukemia (show BCL11A Antibodies) (AML (show RUNX1 Antibodies)).

  8. Studies show a remarkable reduction in tribbles (show TRIB1 Antibodies) 2 protein (Trib2) expression during oocyte maturation whereas tribbles (show TRIB1 Antibodies) 1 protein (Trib1 (show TRIB1 Antibodies)) and tribbles 3 (show TRIB3 Antibodies) protein (Trib3 (show TRIB3 Antibodies)) expression was significantly increased during this process.

  9. The results suggest that TRIB2 is a meaningful biomarker reflecting diagnosis and progression of melanoma, as well as predicting clinical response to chemotherapy.

  10. Data suggest that TRB2 exhibits metal-independent autophosphorylation activity, low affinity ATP binding/hydrolysis, and a conserved catalytic lysine residue in the active site (rather than the asparagine in many metal-dependent kinases).

Mouse (Murine) Tribbles Homolog 2 (Drosophila) (TRIB2) interaction partners

  1. TRIB1 (show TRIB1 Antibodies) and TRIB3 (show TRIB3 Antibodies) are more strongly expressed than TRIB2 in cumulus cells (CC) surrounding oocytes from preovulatory follicles than in CC of immature ones.

  2. we identify the contribution of dysregulated C/EBPalpha (show CEBPA Antibodies) and E2F1 (show E2F1 Antibodies) to elevated Trib2 expression and leukemic cell survival

  3. Trib2 transduced hematopoietic stem cells developed acute myeloid leukemia (show BCL11A Antibodies).

  4. Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients.

  5. Data identify Tribbles homolog 2 as an oncogene (show RAB1A Antibodies) that induces acute myelogenous leukemia through a mechanism involving inactivation of C/EBPalpha (show CEBPA Antibodies).

  6. describe suppression of adipocyte differentiation by TRBs Trib1 (show TRIB1 Antibodies), Trib2, Trib3 (show TRIB3 Antibodies)

  7. Mice reconstituted with HSC (show FUT1 Antibodies) cotransduced with HoxA9 (show HOXA9 Antibodies) and Trib2 had accelerated onset of AML (show RUNX1 Antibodies) compared to either gene alone

  8. Linkage of Meis1 (show MEIS1 Antibodies) leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3 (show CCL3 Antibodies).

  9. These results suggest that Trb2 plays minimal roles during kidney and mouse development.

Tribbles Homolog 2 (Drosophila) (TRIB2) Antigen Profile

Protein Summary

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with TRIB2

  • tribbles homolog 2 (Drosophila) (TRIB2) antibody
  • tribbles homolog 2 (Drosophila) (trib2) antibody
  • tribbles homolog 2 (trib2) antibody
  • tribbles homolog 2 (LOC100357208) antibody
  • tribbles homolog 2 (Drosophila) (Trib2) antibody
  • AW319517 antibody
  • C5FW antibody
  • GS3955 antibody
  • RGD1564451 antibody
  • TRB-2 antibody
  • TRB2 antibody
  • TRIB2 antibody
  • xtrb2 antibody
  • Xtrbl antibody

Protein level used designations for TRIB2

tribbles homolog 2 (Drosophila) , tribbles homolog 2-like , tribbles homolog 2 , serine/threonine protein kinase , tribbles-like protein 2 , TRB-2

GENE ID SPECIES
459038 Pan troglodytes
100331041 Danio rerio
394677 Xenopus (Silurana) tropicalis
100357208 Oryctolagus cuniculus
100528799 Ictalurus punctatus
378920 Xenopus laevis
378919 Gallus gallus
28951 Homo sapiens
403884 Canis lupus familiaris
352960 Bos taurus
217410 Mus musculus
313974 Rattus norvegicus
100173599 Pongo abelii
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