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TRPS1 encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Additionally we are shipping TRPS1 Antibodies (22) and and many more products for this protein.
TRPS1 gene was responsible for most of the TRPS phenotype
Data show that co-silencing of tricho-rhino (show RHNO1 ELISA Kits)-phalangeal-syndrome (TRPS1) and cathepsin D (show CTSD ELISA Kits) (Cath-D) in breast cancer cells (BCC) affects the transcription of cell cycle and proliferation.
Trps1 plays a crucial role in osteosarcoma angiogenesis, metastasis and clinical surgical stage.
Single nucleotide polymorphisms in TRPS1 gene is associated with Coronary Artery Disease.
Missense mutations are located exclusively in exon 6 and 7 of TRPS1 in patients with tricho-rhino (show RHNO1 ELISA Kits)-phalangeal syndrome.
TRPS1 haploinsufficiency results in STAT3 (show STAT3 ELISA Kits) and SOX9 (show SOX9 ELISA Kits) mRNA expression in Trichorhinophalangeal syndrome.
Trps1 is involved in non-anastomotic biliary structure pathogenesis following liver transplantation and negatively correlates with biliary epithelial cell epithelial-mesenchymal transition and biliary fibrosis in liver grafts.
our study proposes that TRPS1 acts as a central hub in the control of cell cycle and proliferation during cancer development
Identification of a novel missense mutation c.2726G>A (p.C909Y) of the TRPS1 gene in a family with trichorhinophalangeal syndrome type I.
we identified a mutation in the TRPS1 gene The same mutation was detected as a 10% mosaic mutation by Pyrosequencing in blood-derived DNA from his healthy mother. this is the first time that somatic mosaicism has been identified in TRPSI
our findings partially explain why patients with TRPS show a broad range of congenital cardiac defects, although Trps1 expression is observed in a more restricted fashion.
Taken together, these results show that hair follicle development in Trps1 KO embryos is impaired directly or indirectly by decreased Noggin (show NOG ELISA Kits) expression.
association between SNP within TRPS1 and BMD (show BEST1 ELISA Kits)
Trps1 acts as a regulator of hdac1 (show HDAC1 ELISA Kits) and hdac4 (show HDAC5 ELISA Kits) histone deacetylases during mitosis.
The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta (show TGFB1 ELISA Kits) signaling.
We found that Trps1 directly represses expression of the hair follicle stem cell regulator Sox9 (show SOX9 ELISA Kits) to control proliferation of the follicle epithelium.
Trps1 is identified as a potent inhibitor of Dspp (show DSPP ELISA Kits) expression and the subsequent mineralization of dentin.
analysis of control of mesenchymal lineage progression by microRNAs targeting skeletal gene regulators Trps1 and Runx2 (show RUNX2 ELISA Kits)
These observations underscore the indispensable role played by Trps1 in normal temporomandibular joint development.
Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density
This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III.
trichorhinophalangeal syndrome I homolog
, zinc finger transcription factor Trps1
, tricho-rhino-phalangeal syndrome type I protein
, zinc finger protein GC79
, atypical GATA protein TRPS1