You are viewing an incomplete version of our website. Please click to reload the website as full version.

Trimethyllysine Hydroxylase, epsilon Proteins (TMLHE)

TMLHE encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Additionally we are shipping Trimethyllysine Hydroxylase, epsilon Antibodies (54) and Trimethyllysine Hydroxylase, epsilon Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TMLHE 55217 Q9NVH6
TMLHE 192289 Q91ZE0
TMLHE 170898 Q91ZW6
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Trimethyllysine Hydroxylase, epsilon Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,125.83
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,125.83
Details

TMLHE Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Trimethyllysine Hydroxylase, epsilon (TMLHE) Interaction Partners

Human Trimethyllysine Hydroxylase, epsilon (TMLHE) interaction partners

  1. Study found 3 mutations in TMLHE to be associated with autism spectrum disorder, c.229C>T/p.Arg77X, c.730G>C/p.Asp244His, and c.1107G>T/p.Glu369Asp.

  2. TMLHE deficiency is common in control males and was not significantly increased in frequency in probands from simplex autism families, however, it was 2.82-fold more frequent in probands from male-male multiplex autism families.

  3. Use of array CGH to detect exonic copy number variants throughout the genome in autism families detects a novel deletion in TMLHE.

  4. C-terminal region of trimethyllysine hydroxylase, epsilon contains the main determinants for its enzymatic activity including a key H389 residue

  5. By 5' and 3' RACE, we identified and mapped two alternative 5' TMLH first exons and seven alternative 3'-splice variants.

Mouse (Murine) Trimethyllysine Hydroxylase, epsilon (TMLHE) interaction partners

  1. C-terminal region of TMLH contains the main determinants for its enzymatic activity including a key H389 residue

  2. TMLH expression is present at E12.5 dpc in the liver, lung and brain, and is then maintained in the postnatal brain with a specific neuronal pattern.

Trimethyllysine Hydroxylase, epsilon (TMLHE) Protein Profile

Protein Summary

This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with TMLHE

  • trimethyllysine hydroxylase, epsilon (TMLHE)
  • trimethyllysine hydroxylase, epsilon (tmlhe)
  • trimethyllysine hydroxylase, epsilon (LOC100230324)
  • trimethyllysine hydroxylase, epsilon (Tmlhe)
  • AUTSX6 protein
  • Bbox2 protein
  • D430017M14Rik protein
  • TMLD protein
  • Tmlh protein
  • TMLHED protein
  • XAP130 protein

Protein level used designations for TMLHE

trimethyllysine hydroxylase, epsilon , TML hydroxylase , TML-alpha-ketoglutarate dioxygenase , butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 2 , epsilon-trimethyllysine 2-oxoglutarate dioxygenase , epsilon-trimethyllysine hydroxylase , trimethyllysine dioxygenase, mitochondrial , TML dioxygenase , TMLD , butyrobetaine (gamma), 2-oxoglutarate dioxygenase 2 (gamma-butyrobetaine hydroxylase)

GENE ID SPECIES
465953 Pan troglodytes
481090 Canis lupus familiaris
703711 Macaca mulatta
100124877 Xenopus (Silurana) tropicalis
100189568 Xenopus laevis
100230324 Taeniopygia guttata
100338782 Oryctolagus cuniculus
100595389 Nomascus leucogenys
55217 Homo sapiens
192289 Mus musculus
170898 Rattus norvegicus
535630 Bos taurus
422296 Gallus gallus
Selected quality suppliers for Trimethyllysine Hydroxylase, epsilon Proteins (TMLHE)
Did you look for something else?