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TPI encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Additionally we are shipping Triosephosphate Isomerase Proteins (12) and Triosephosphate Isomerase Kits (3) and many more products for this protein.
Showing 10 out of 37 products:
Human Polyclonal TPI Primary Antibody for IHC, ELISA - ABIN185349
Jiang, Gan, Huang, Shen, Wang, Yao: Proteomics-based identification of proteins with altered expression induced by 12-O-tetradecanoylphorbol 13-acetate in nasopharyngeal carcinoma CNE2 cells. in Acta biochimica et biophysica Sinica 2005
Show all 3 references for ABIN185349
Human Polyclonal TPI Primary Antibody for IF (p), IHC (p) - ABIN752968
Yao, Zhuang, Du, Cheng, Yang, Guan, Hu, Zhu, Christine, Shi, Hua: Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation. in Molecular & cellular proteomics : MCP 2013
our findings are the first to identify, to our knowledge, a functional synaptic defect in TPI (show TPI1 Antibodies) deficiency derived from molecular changes in the TPI (show TPI1 Antibodies) dimer interface.
TIMELESS (show TIMELESS Antibodies) mutants unable to bind PARP1 (show PARP1 Antibodies). TIMELESS (show TIMELESS Antibodies) silencing significantly impairs DNA double-strand break repair.
Data reports the crystal structure of Timeless (show TIMELESS Antibodies)-PARP-1 (show PARP1 Antibodies) complex and provides evidence that Timeless (show TIMELESS Antibodies) is recruited to sites of DNA damage through PARP-1 (show PARP1 Antibodies) to mediate homologous recombination repair of DNA double-strand breaks.
Polyvinylpyrrolidone stabilised silver nanoparticles (60 nM; 2-6 nm diameter) selectively inhibited PfTIM with a 7-fold decrease in enzyme catalytic efficiency (K(cat)/K (show CTSK Antibodies)(m)) over hTIM (show TIMELESS Antibodies).
overexpression of TIM exerts oncogenic function in human HCCs (show HCCS Antibodies), which is mediated via CHEK2 (show CHEK2 Antibodies) and EEF1A2 (show EEF1A2 Antibodies).
TIMELESS (show TIMELESS Antibodies) and RORA (show RORA Antibodies) genes may confer susceptibility to bipolar disorders and impact on circadian phenotypes
results suggest amyloid-beta oligomers induce neuronal death by triggering methylglyoxal(MG) production; increased release of MG is a direct consequence of triosephosphate isomerase (show TPI1 Antibodies) nitrotyrosination due to amyloid-beta peptide action at the 2 tyrosines associated with the catalytic center
The results of this study suggest that the TIMELESS (show TIMELESS Antibodies) gene may be associated with the lithium prophylactic response in bipolar illness.
TPI (show TPI1 Antibodies)-PEP (show PAEP Antibodies) co-crystal structure, demonstrating that PEP (show PAEP Antibodies) directly binds into the catalytic pocket of TPI (show TPI1 Antibodies).
TIMELESS (show TIMELESS Antibodies) is frequently overexpressed in various types of tumor tissues, and elevated TIMELESS (show TIMELESS Antibodies) expression is associated with advanced tumor stage and poorer breast cancer prognosis.
TPI (show TPI1 Antibodies) interacts with Tau protein in a normal, nondisease state as well as in a neurodegenerative state.
Triosephosphate isomerase (show TPI1 Antibodies) activity-deficient mice show haemolytic anaemia in homozygous condition
This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
, protein timeless homolog
, timeless circadian clock 1
, timeless homolog
, triose-phosphate isomerase
, triosephosphate isomerase
, triosephosphate isomerase (TIM, D-glyceraldehyde 3-phosphate ketol-isomerase)