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Triosephosphate Isomerase Proteins (TPI)

TPI encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Additionally we are shipping Triosephosphate Isomerase Antibodies (37) and Triosephosphate Isomerase Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Human TPI TPI 8914 Q9UNS1
Rat TPI TPI 500959  
Mouse TPI TPI 21991 P17751
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Top Triosephosphate Isomerase Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
Yeast Platanus orientalis His tag 1 mg Log in to see 56 to 66 Days
$2,132.17
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Yeast REACT_West Indian ocean coelacanth His tag 1 mg Log in to see 56 to 66 Days
$2,632.67
Details
Yeast REACT_Pork tapeworm His tag 1 mg Log in to see 56 to 66 Days
$2,641.83
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Yeast Leishmania His tag 1 mg Log in to see 56 to 66 Days
$2,643.67
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Yeast REACT_Culex pipiens pipiens His tag 1 mg Log in to see 56 to 66 Days
$2,504.33
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Yeast Mosquito His tag 1 mg Log in to see 56 to 66 Days
$2,504.33
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Yeast Aedes togoi His tag 1 mg Log in to see 56 to 66 Days
$2,504.33
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Yeast Bombyx mori His tag 1 mg Log in to see 56 to 66 Days
$2,632.67
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Yeast Plasmodium falciparum His tag 1 mg Log in to see 56 to 66 Days
$2,634.50
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Yeast Rice His tag 1 mg Log in to see 56 to 66 Days
$2,647.33
Details

More Proteins for Triosephosphate Isomerase (TPI) Interaction Partners

Human Triosephosphate Isomerase (TPI) interaction partners

  1. our findings are the first to identify, to our knowledge, a functional synaptic defect in TPI (show TPI1 Proteins) deficiency derived from molecular changes in the TPI (show TPI1 Proteins) dimer interface.

  2. TIMELESS mutants unable to bind PARP1. TIMELESS silencing significantly impairs DNA double-strand break repair.

  3. Data reports the crystal structure of Timeless-PARP-1 (show PARP1 Proteins) complex and provides evidence that Timeless is recruited to sites of DNA damage through PARP-1 (show PARP1 Proteins) to mediate homologous recombination repair of DNA double-strand breaks.

  4. Polyvinylpyrrolidone stabilised silver nanoparticles (60 nM; 2-6 nm diameter) selectively inhibited PfTIM with a 7-fold decrease in enzyme catalytic efficiency (K(cat)/K(m)) over hTIM.

  5. overexpression of TIM exerts oncogenic function in human HCCs (show HCCS Proteins), which is mediated via CHEK2 (show CHEK2 Proteins) and EEF1A2 (show EEF1A2 Proteins).

  6. TIMELESS and RORA (show RORA Proteins) genes may confer susceptibility to bipolar disorders and impact on circadian phenotypes

  7. results suggest amyloid-beta oligomers induce neuronal death by triggering methylglyoxal(MG) production; increased release of MG is a direct consequence of triosephosphate isomerase (show TPI1 Proteins) nitrotyrosination due to amyloid-beta peptide action at the 2 tyrosines associated with the catalytic center

  8. The results of this study suggest that the TIMELESS gene may be associated with the lithium prophylactic response in bipolar illness.

  9. TPI (show TPI1 Proteins)-PEP (show PAEP Proteins) co-crystal structure, demonstrating that PEP (show PAEP Proteins) directly binds into the catalytic pocket of TPI (show TPI1 Proteins).

  10. TIMELESS is frequently overexpressed in various types of tumor tissues, and elevated TIMELESS expression is associated with advanced tumor stage and poorer breast cancer prognosis.

Mouse (Murine) Triosephosphate Isomerase (TPI) interaction partners

  1. TPI (show TPI1 Proteins) interacts with Tau protein in a normal, nondisease state as well as in a neurodegenerative state.

  2. Triosephosphate isomerase (show TPI1 Proteins) activity-deficient mice show haemolytic anaemia in homozygous condition

Pig (Porcine) Triosephosphate Isomerase (TPI) interaction partners

  1. Sperm TPI content and amounts of GPX5 in seminal plasma may be used as quality markers of boar sperm.

Triosephosphate Isomerase (TPI) Protein Profile

Protein Summary

This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with TPI

  • timeless circadian clock (TIMELESS)
  • triosephosphate isomerase (LOC500959)
  • triosephosphate isomerase (Tpi)
  • triosephosphate isomerase 1 (TPI1)
  • triosephosphate isomerase 1 (Tpi1)
  • AI255506 protein
  • hTIM protein
  • TIM protein
  • TIM1 protein
  • Tpi protein
  • Tpi-1 protein

Protein level used designations for TPI

Tof1 homolog , protein timeless homolog , timeless circadian clock 1 , timeless homolog , TIM , triose-phosphate isomerase , triosephosphate isomerase , triosephosphate isomerase (TIM, D-glyceraldehyde 3-phosphate ketol-isomerase)

GENE ID SPECIES
8914 Homo sapiens
500959 Rattus norvegicus
100146104 Bombyx mori
7167 Homo sapiens
21991 Mus musculus
477711 Canis lupus familiaris
281543 Bos taurus
396435 Gallus gallus
100157582 Sus scrofa
24849 Rattus norvegicus
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