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The protein encoded by TRIM11 is a member of the tripartite motif (TRIM) family. Additionally we are shipping Tripartite Motif Containing 11 Proteins (6) and many more products for this protein.
Showing 10 out of 79 products:
Human Polyclonal TRIM11 Primary Antibody for IHC (p), IHC - ABIN249839
Reymond, Meroni, Fantozzi, Merla, Cairo, Luzi, Riganelli, Zanaria, Messali, Cainarca, Guffanti, Minucci, Pelicci, Ballabio: The tripartite motif family identifies cell compartments. in The EMBO journal 2001
TRIM11 is a host cellular factor that interferes with the early steps of HIV-1 replication and provides a connection between viral protein and host antiviral factors.
TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.
TRIM11 negatively regulates IFN-beta (show IFNB1 Antibodies) production and antiviral activity by targeting TBK1 (show TBK1 Antibodies).
Study shows that the E3 ubiquitin ligase (show MUL1 Antibodies) TRIM11 plays a critical role in the clearance of mutant PHOX2B (show PHOX2B Antibodies), which causes congenital central hypoventilation syndrome, through the proteasome.
PAX6 (show PAX6 Antibodies) interacts with HOMER3 (show HOMER3 Antibodies), DNCL1 (show DYNLL1 Antibodies), and TRIM11. Three C-terminal PAX6 (show PAX6 Antibodies) mutations, previously identified in patients with eye malformations, all reduced or abolished the interactions.
These results suggest that TRIM11, with the ubiquitin-proteasome pathway, regulates ARC105 (show MED15 Antibodies) function in TGFbeta (show TGFB1 Antibodies) signaling.
Downregulation of TRIM11 and TRIM15 (show TRIM15 Antibodies) enhanced virus release suggesting that these proteins contribute to the endogenous restriction of retroviruses in cells.
This study suggests a potential role for Trim11 in the specification of NA phenotype by interaction with Phox2b (show PHOX2B Antibodies).
The results suggest that TRIM11 plays a role in the regulation of intracellular humanin level through ubiquitin-mediated protein degradation pathways.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified.
tripartite motif-containing 11
, tripartite motif containing 11
, E3 ubiquitin-protein ligase TRIM11
, RING finger protein 92
, tripartite motif-containing protein 11
, tripartite motif protein 11