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TRIM13 encodes a member of the tripartite motif (TRIM) family. Additionally we are shipping TRIM13 Proteins (5) and many more products for this protein.
Showing 10 out of 56 products:
Cow (Bovine) Polyclonal TRIM13 Primary Antibody for IHC, WB - ABIN2778286
Matsuda, Suzuki, Honda, Muramatsu, Matsuzaki, Nagano, Doi, Shimotohno, Harada, Nishida, Hayashi, Sugano: Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. in Oncogene 2003
TRIM13 mediated NF-kappaB (show NFKB1 Antibodies) repression is essential for negative regulation of clonogenic ability of the cells.
Results show that HRD1 (show SYVN1 Antibodies) and RFP2 contributes are required for the disposal of V247M alpha-sarcoglycan (show SGCA Antibodies) mutant.
This study first time demonstrated the role of TRIM13 as novel regulator of caspase-8 (show CASP8 Antibodies) activation and cell death during endoplasmic reticulum stress.
Shows important roles of TRIM13 in MM tumour survival and proliferation in multiple myeloma.
Results describe the role of TRIM13 in induction of autophagy, which may play an important role in regulation of ER stress and tumor suppression.
Data suggest that irradiation causes RFP2 overexpression, which enhances ionizing radiation-induced apoptosis by increasing p53 (show TP53 Antibodies) stability and decreasing AKT (show AKT1 Antibodies) kinase activity through MDM2 (show MDM2 Antibodies) and AKT (show AKT1 Antibodies) degradation.
Rfp2 contains a C-terminal transmembrane domain indispensable for its localization to the ER
TRIM13, also known as RFP2, promoter area contains multiple quadruplex forming GGGGA-repeats that possesses unusually hight activity, anomalously high electrostatic fields induced by sequence-dependent dipoles and very low nucleosome forming potential.
TRIM13 interacts with MDA5 (show IFIH1 Antibodies) and negatively regulates MDA5 (show IFIH1 Antibodies)-mediated type I IFN production.
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene.
tripartite motif-containing 13
, ret finger protein 2
, B-cell chronic lymphocytic leukemia tumor suppressor Leu5
, CLL-associated RING finger
, E3 ubiquitin-protein ligase TRIM13
, RING finger protein 77
, leukemia-associated protein 5
, putative tumor suppressor RFP2
, tripartite motif protein 13
, tripartite motif-containing protein 13