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The protein encoded by TRIM14 is a member of the tripartite motif (TRIM) family. Additionally we are shipping TRIM14 Antibodies (26) and many more products for this protein.
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Data suggest that tripartite motif containing 14 protein (TRIM14) might play an important role in the malignant progression of tongue squamous cells carcinoma (TSCC) and in regulation of the NF_Kappa B (NF-kappaB (show NFKB1 Proteins)) signaling pathway.
stable enhanced expression of trim14 gene in cells activates the transcription of many immunity genes and suppresses Sindbis virus reproduction, but Sindbis virus infection of HEK (show EPHA3 Proteins)-trim14 cells promotes inhibition of some genes involved in innate immunity.
Upon virus infection, TRIM14 recruits NF-kappaB essential modulator (NEMO) to the MAVS complex via ubiquitin chains.
These results demonstrate the presence of the similar mechanism of trim14 gene action in different types of mammalian cells.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants.
tripartite motif protein TRIM14
, tripartite motif-containing 14
, tripartite motif-containing protein 14-like
, tripartite motif containing 14
, tripartite motif-containing protein 14
, PU.1 binding protein Pub
, PU.1-binding protein
, tripartite motif protein 14