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The protein encoded by TRIM2 is a member of the tripartite motif (TRIM) family. Additionally we are shipping TRIM2 Proteins (3) and TRIM2 Kits (1) and many more products for this protein.
Showing 10 out of 80 products:
Human Polyclonal TRIM2 Primary Antibody for IHC (p), IP - ABIN249847
Thompson, Pearson, Ashley, Jessick, Murphy, Gafken, Henshall, Morris, Simon, Meller: Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection. in The Journal of biological chemistry 2011
Show all 2 references for ABIN249847
Human Polyclonal TRIM2 Primary Antibody for IHC, ELISA - ABIN184974
Reymond, Meroni, Fantozzi, Merla, Cairo, Luzi, Riganelli, Zanaria, Messali, Cainarca, Guffanti, Minucci, Pelicci, Ballabio: The tripartite motif family identifies cell compartments. in The EMBO journal 2001
Studies indicate most-studied TRIpartite Motif (TRIM (show TRAT1 Antibodies))-NHL (show RTEL1 Antibodies) proteins TRIM2, TRIM3 (show TRIM3 Antibodies), TRIM32 (show TRIM32 Antibodies) and TRIM71 (show TRIM71 Antibodies), and their mutations have been linked to diseases.
TRIM2 homozygous missense mutation (c.2000A>C; p.D667A) in a patient with peripheral neuropathy and bilateral vocal cord paralysis
The functional role of the C-terminal NHL (show RTEL1 Antibodies) domain was characterized in TRIM2.
TRIM2 is repressed by miR (show MLXIP Antibodies)-9 and -181c, either alone or in combination.
a role for TRIM2 in mediating the p42/p44 (show PSMC6 Antibodies) MAPK (show MAPK3 Antibodies)-dependent ubiquitination of Bim (show BCL2L11 Antibodies) in rapid ischemic tolerance.
Trim2 has an important function in the regulation of axon outgrowth during development.
TRIM2 is an ubiquitin ligase and point to a mechanism regulating neurofilament light subunit metabolism through an ubiquitination pathway that, if deregulated, triggers neurodegeneration
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. Its function has not been identified.
E3 ubiquitin-protein ligase TRIM2
, RING finger protein 86
, tripartite motif protein 2
, tripartite motif protein TRIM2
, tripartite motif-containing 2
, tripartite motif-containing protein 2
, Tripartite motif-containing protein 2
, neural activity-related ring finger protein