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anti-Tripartite Motif Containing 21 (TRIM21) Antibodies

TRIM21 encodes a member of the tripartite motif (TRIM) family. Additionally we are shipping TRIM21 Proteins (17) and TRIM21 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRIM21 6737 P19474
TRIM21 20821  
TRIM21 308901  
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Top anti-TRIM21 Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated EIA, IHC (p), WB AP22453PU-N TRIM21 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Colon at 5 µg/ml using Biotin conjugated anti-Goat IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human TRIM21 with C-terminal MYC tag probed with AP22453PU-N TRIM21 antibody (1 µg/ml) in Lane A and probed with anti-MYC Tag (1/1000) in Lane C. Mock-transfected HEK293 probed with AP22453PU-N (1 mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Uterus (formalin-fixed, paraffin-embedded) stained with TRIM21 antibody ABIN364487 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with TRIM21 antibody ABIN364487 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Goat Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated IHC (p), ELISA Human Colon (formalin-fixed, paraffin-embedded) stained with TRIM21 antibody ABIN337310 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details

TRIM21 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) ,


Top referenced anti-TRIM21 Antibodies

  1. Dog (Canine) Polyclonal TRIM21 Primary Antibody for WB - ABIN2778305 : Yamochi, Ohnuma, Hosono, Tanaka, Kanai, Morimoto: SSA/Ro52 autoantigen interacts with Dcp2 to enhance its decapping activity. in Biochemical and biophysical research communications 2008 (PubMed)

  2. Human Polyclonal TRIM21 Primary Antibody for EIA, IHC (p) - ABIN569661 : Chan, Di Donato, Hamel, Tseng, Buyon: 52-kD SS-A/Ro: genomic structure and identification of an alternatively spliced transcript encoding a novel leucine zipper-minus autoantigen expressed in fetal and adult heart. in The Journal of experimental medicine 1995 (PubMed)

More Antibodies against TRIM21 Interaction Partners

Human Tripartite Motif Containing 21 (TRIM21) interaction partners

  1. The interaction of TRIM21 and LFG (show FAIM2 Antibodies) was analyzed by co-immunoprecipitation. To examine changes in regulatory processes, western blot analyses, real-time PCR, activity of apoptotic process and flow cytometric analyses were carried out.

  2. TRIM21 plays an essential role in p62-regulated redox homeostasis and may be a viable target for treating pathological conditions resulting from oxidative damage.

  3. TRIM21-induced exposure of the viral genome promotes sensing of DNA and RNA viruses by cGAS and RIG-I (show DDX58 Antibodies)

  4. we prove that TRIM21 is a potential tumor suppressor in hepatocellular carcinoma and its low expression indicates poor prognosis

  5. Trim21 regulates Nmi (show MYO1C Antibodies)-IFI35 (show IFI35 Antibodies) complex-mediated inhibition of innate antiviral response

  6. TRIM20 (show MEFV Antibodies) and TRIM21 mediate precision autophagy, controlling the hub signaling machineries and key factors, inflammasome and type I interferon (show IFNA Antibodies), directing cardinal (show CARD8 Antibodies) innate immunity response systems in humans.

  7. This study elucidates a complex mechanism of step-wise ubiquitination and deubiquitination activities that allows contemporaneous innate immune signaling and neutralization by TRIM21.

  8. Anti-Ro52/TRIM21 antibodies are independently associated with the presence of interstitial lung disease and poor survival in systemic sclerosis.

  9. Endoplasmic reticulum stress causes autophagy and apoptosis leading to cellular redistribution of the SS-A and SS-B autoantigens in salivary gland epithelial cells of Sjogren's syndrome patients.

  10. These data extend the protective role of TRIM21 from viruses to bacteria and thereby strengthening the general role of antibody-dependent intracellular neutralisation in cellular immunity.

Cow (Bovine) Tripartite Motif Containing 21 (TRIM21) interaction partners

Mouse (Murine) Tripartite Motif Containing 21 (TRIM21) interaction partners

  1. Antibody affinity modulates TRIM21 immune function. TRIM21 mediates neutralization under suboptimal conditions, whereas induction of immune signaling is balanced according to the functional affinity for the incoming immune stimuli.

  2. TRIM21 plays an essential role in p62-regulated redox homeostasis and may be a viable target for treating pathological conditions resulting from oxidative damage.

  3. Trim21, an estrogen receptor (show ESR1 Antibodies) coactivator, induces MYC (show MYC Antibodies) oncogene (show RAB1A Antibodies) by removing repressive CoAA (show RBM14 Antibodies) through E2-dependent degradation of CoAA (show RBM14 Antibodies).

  4. results demonstrate that TRIM21 provides potent antiviral protection and forms an important part of the humoral immune response

  5. Simultaneous neutralization and innate immune detection of replicating mouse adenovirus type 1 by TRIM21.

  6. Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor (show FCGRT Antibodies) TRIM21.

  7. TRIM21 is an interferon (show IFNA Antibodies)-inducible E3 ligase that induces the Lys48-linked ubiquitination and degradation of DDX41 (show DDX41 Antibodies) and negatively regulates the innate immune response to intracellular double-stranded DNA.

  8. analysis of a novel role for tyrosine phosphorylation in regulating the interaction with IRF3 (show IRF3 Antibodies) and the activity of TRIM21 downstream of TLR3 (show TLR3 Antibodies) and TLR4 (show TLR4 Antibodies)

  9. Ro52 is an E3 ligase for interferon (show IFNA Antibodies) regulatory factor (IRF)-8 (show IRF8 Antibodies) that acts in a non-degradation pathway of ubiquitination and contributes to the elicitation of innate immunity in macrophages.

  10. TRIM21 is a previously undescribed type of IgG receptor based on a non-Ig scaffold whose interaction at the fundamental level-structural, thermodynamic, and kinetic-is evolutionarily conserved.

TRIM21 Antigen Profile

Protein Summary

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Gene names and symbols associated with TRIM21

  • tripartite motif containing 21 (TRIM21) antibody
  • tripartite motif-containing 21 (TRIM21) antibody
  • tripartite motif-containing 21 (Trim21) antibody
  • RNF81 antibody
  • Ro52 antibody
  • SSA antibody
  • Ssa1 antibody

Protein level used designations for TRIM21

tripartite motif-containing 21 , 52 kDa Ro protein-like , tripartite motif containing 21 , 52 kDa Ro protein , 52 kDa ribonucleoprotein autoantigen Ro/SS-A , E3 ubiquitin-protein ligase TRIM21 , RING finger protein 81 , SS-A , Sicca syndrome antigen A , Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro) , ro(SS-A) , sjoegren syndrome type A antigen , tripartite motif-containing protein 21 , 52kD Ro/SSA autoantigen , Sjogren syndrome antigen A1 , tripartite motif protein 21

GENE ID SPECIES
717826 Macaca mulatta
100387049 Callithrix jacchus
100454593 Pongo abelii
100601201 Nomascus leucogenys
6737 Homo sapiens
100302538 Sus scrofa
359715 Bos taurus
485226 Canis lupus familiaris
20821 Mus musculus
308901 Rattus norvegicus
Selected quality suppliers for anti-TRIM21 (TRIM21) Antibodies
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