Tripartite Motif Containing 24 (TRIM24) ELISA Kits

The protein encoded by TRIM24 mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. Additionally we are shipping TRIM24 Antibodies (118) and TRIM24 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TRIM24 8805 O15164
TRIM24 21848 Q64127
Anti-Rat TRIM24 TRIM24 500084  
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More ELISA Kits for TRIM24 Interaction Partners

Human Tripartite Motif Containing 24 (TRIM24) interaction partners

  1. Study showed that TRIM24 was upregulated during gastric carcinogenesis and demonstrated that TRIM24 was a functional target gene of miR (show MLXIP ELISA Kits)-511, and miR (show MLXIP ELISA Kits)-511 inactivated PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) and Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathways by suppressing TRIM24.

  2. Overexpression of KAT6A (show MYST3 ELISA Kits) or TRIM24 promoted PIK3CA (show PIK3CA ELISA Kits) expression, AKT (show AKT1 ELISA Kits) phosphorylation, and cell proliferation.

  3. we identified altered glucose metabolism in the progression of head and neck squamous cell carcinoma and showed that it could be partially attributed to the novel link between GLUT4 (show SLC2A4 ELISA Kits) and TRIM24

  4. This study concluded that reduced TRIM24 protein is associated with poor survival in esophageal squamous cell cancer (ESCC) patients, suggesting TRIM24 protein is a potential prognostic biomarker for ESCC.

  5. Data suggest that, in cardiomyocytes, TRIM32 attenuates activation of SRF signaling and hypertrophy due to dysbindin; TRIM24 promotes these effects. TRIM32 promotes dysbindin degradation; TRIM24 protects dysbindin from degradation. (TRIM = tripartite motif-containing protein; SRF = serum response factor)

  6. hypothesis of "synergistic modification induced recognition" is then proposed to link histone modification and TRIM24 binding

  7. Report provides evidence for an oncogenic role for TRIM24 as a transcriptional activator and mediator of hormone-refractory prostate cancer cell growth in SPOP (show SPOP ELISA Kits) mutant and castration-resistant prostate cells.

  8. TRIM24 expression is positively correlated with Acetylated H3 lysine 23 levels, and high levels of both TRIM24 and Acetylated H3 lysine 23 predict shorter overall survival of breast cancer patients.

  9. TRIM24 regulate resistance to Gefitinib via Akt (show AKT1 ELISA Kits) pathway in non-small cell lung cancer cells.

  10. TRIM24 is overexpressed in human bladder cancer and facilitates bladder cancer growth and invasion, possibly through NF-kappaB (show NFKB1 ELISA Kits) and AKT (show AKT1 ELISA Kits) signaling pathways.

Mouse (Murine) Tripartite Motif Containing 24 (TRIM24) interaction partners

  1. Maintenance of pluripotency is regulated by a network of transcription factors coordinated by Oct4 (show POU5F1 ELISA Kits), Sox2 (show SOX2 ELISA Kits), and Nanog (show NANOG ELISA Kits); Trim24 significantly improved efficiency of cellular reprogramming, demonstrating its direct functionality in establishing pluripotency.

  2. data identify a previously unappreciated Trim24-dependent requirement for IL-1R expression on TH2 cells and an important nonredundant role for T-cell-intrinsic Trim24 in TH2-mediated allergy and antihelminth immunity

  3. Trim24 repressed VL30-class endogenous retroviruses retrotransposons

  4. These results identify Trim24 as a novel negative regulator of the IFN/STAT (show STAT1 ELISA Kits) pathway and suggest that this repression through Rara (show RARA ELISA Kits) inhibition may prevent liver cancer.

  5. Somatic hepatocyte-specific inactivation of TRIM24, TRIM28 (show TRIM28 ELISA Kits), or TRIM33 (show TRIM33 ELISA Kits) all promote hepatocellular carcinoma in a cell-autonomous manner in mice.

  6. TRIM24 regulates AR-mediated transcription in collaboration with TIP60 (show KAT5 ELISA Kits) and BRD7 (show BRD7 ELISA Kits).

  7. TIF1alpha-chromatin association is direct and involves DNA and nucleosome interactions mediated by the bromodomain

  8. These studies indicate that TIF1alpha is a factor that modulates the expression of a set of genes during the first wave of genome activation in the mouse embryo.

  9. The results not only provide genetic evidence that Trim24 and Rara (show RARA ELISA Kits) co-regulate hepatocarcinogenesis in an antagonistic manner but also suggest that aberrant activation of Rara (show RARA ELISA Kits) is deleterious to liver homeostasis.

  10. TIF1alpha-null mutant pathological phenotype supports the hypothesis that aging is promoted by increased activity of the vitamin D signaling pathway

TRIM24 Antigen Profile

Antigen Summary

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with TRIM24

  • tripartite motif containing 24 (TRIM24) antibody
  • tripartite motif containing 24 (trim24) antibody
  • transcription intermediary factor 1-alpha (LOC100548578) antibody
  • tripartite motif containing 24 S homeolog (trim24.S) antibody
  • tripartite motif-containing 24 (Trim24) antibody
  • A130082H20Rik antibody
  • AI447469 antibody
  • D430004I05Rik antibody
  • hTIF1 antibody
  • ptc6 antibody
  • rnf82 antibody
  • tf1a antibody
  • tif1 antibody
  • TIF1-alpha antibody
  • Tif1a antibody
  • TIF1alpha antibody
  • TRIM24 antibody

Protein level used designations for TRIM24

tripartite motif-containing 24 , transcriptional intermediary factor 1 alpha , tripartite motif containing 24 , E3 ubiquitin-protein ligase TRIM24 , RING finger protein 82 , TIF1-alpha , transcription intermediary factor 1-alpha , transcriptional intermediary factor 1 , E3 ubiquitin-protein ligase Trim24 , transcriptional intermediary factor 1, alpha , tripartite motif-containing protein 24 , Ab2-427

418106 Gallus gallus
463762 Pan troglodytes
537246 Bos taurus
710229 Macaca mulatta
100158542 Xenopus (Silurana) tropicalis
100348283 Oryctolagus cuniculus
100548578 Meleagris gallopavo
100558013 Anolis carolinensis
100597413 Nomascus leucogenys
8805 Homo sapiens
495130 Xenopus laevis
21848 Mus musculus
500084 Rattus norvegicus
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