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Tripartite Motif Containing 25 (TRIM25) ELISA Kits

The protein encoded by TRIM25 is a member of the tripartite motif (TRIM) family. Additionally we are shipping TRIM25 Antibodies (132) and TRIM25 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TRIM25 7706 Q14258
Anti-Mouse TRIM25 TRIM25 217069 Q61510
Anti-Rat TRIM25 TRIM25 494338  
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More ELISA Kits for TRIM25 Interaction Partners

Human Tripartite Motif Containing 25 (TRIM25) interaction partners

  1. TRIM25 may exert its function through TGF-beta (show TGFB1 ELISA Kits) pathway.

  2. TRIM25 plays an additional role in RIG-I (show DDX58 ELISA Kits)/MDA5 (show IFIH1 ELISA Kits) signaling other than RIG-I (show DDX58 ELISA Kits) ubiquitination via activation of NF-kappaB (show NFKB1 ELISA Kits).

  3. Data show that TRIM25 enhances p53 (show TP53 ELISA Kits) and Mdm2 (show MDM2 ELISA Kits) abundance by preventing their proteasomal degradation. At the same time, TRIM25 inhibits p53 (show TP53 ELISA Kits)'s transcriptional activity and dampens the response to DNA damage.

  4. The PR-2B DENV-2 produced increased levels of subgenomic flavivirus RNA (sfRNA) relative to genomic RNA during replication. PR-2B sfRNA showed sequence dependent binding to and prevention of tripartite motif 25 (TRIM25) deubiquitylation, which is critical for sustained and amplified retinoic acid-inducible gene 1 (show RARRES3 ELISA Kits) (RIG-I (show DDX58 ELISA Kits))-induced type I interferon (show IFNA ELISA Kits) expression.

  5. Trim25 binds to the conserved terminal loop (CTL) of pre-let-7 and activates TuT4 (show ZCCHC11 ELISA Kits), allowing for more efficient Lin28a (show LIN28A ELISA Kits)-mediated uridylation.

  6. Our data uncovers a previously unknown functional link between gp78 (show AMFR ELISA Kits) and TRIM25 and provides mechanistic insight into gp78 (show AMFR ELISA Kits)-mediated protein ubiquitylation.

  7. Data indicate ubiquitin-specific protease 15 (USP15 (show USP15 ELISA Kits)) as a critical regulator of the tripartite motif protein 25 (TRIM25)- and RNA sensor retinoic acid-inducible gene-I (RIG-I (show DDX58 ELISA Kits))-mediated antiviral immune response

  8. In controls, RNF125 (show RNF125 ELISA Kits) is the highest expressed gene, whereas in HIV infection progressors, RIG-I (show DDX58 ELISA Kits) is either the highest expressed gene or is expressed similarly to RNF125 (show RNF125 ELISA Kits) and TRIM25.

  9. Study reports that RLR (show DHX58 ELISA Kits) activation triggers MAVS (show MAVS ELISA Kits) ubiquitination on lysine 7 and 10 by the E3 ubiquitin ligase TRIM25 and marks it for proteasomal degradation concomitantly with downstream signaling.

  10. 14-3-3epsilon is essential for the stable interaction of RIG-I (show DDX58 ELISA Kits) with TRIM25, which facilitates RIG-I (show DDX58 ELISA Kits) ubiquitination and initiation of innate immunity against hepatitis C virus and other pathogenic RNA viruses.

Mouse (Murine) Tripartite Motif Containing 25 (TRIM25) interaction partners

  1. Two key residues (Asp (show C3 ELISA Kits)(488) and Trp (show TYRP1 ELISA Kits)(621)) in the TRIM25 B30.2 domain are critical for binding to the RIG-I (show DDX58 ELISA Kits) CARDs.

  2. Two well-known E3 ubiquitin ligases, Trim25 (also called Efp) and Trim71 (show TRIM71 ELISA Kits) (also called Lin41 (show TRIM71 ELISA Kits)), are validated as RNA-binding proteins, revealing a potential link between RNA biology and protein-modification pathways.

TRIM25 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Gene names and symbols associated with TRIM25

  • tripartite motif containing 25 (TRIM25) antibody
  • tripartite motif-containing 25 (trim25) antibody
  • tripartite motif containing 25 (trim25) antibody
  • tripartite motif-containing 25 (Trim25) antibody
  • AA960166 antibody
  • AL022677 antibody
  • Efp antibody
  • MGC130751 antibody
  • RNF147 antibody
  • Z147 antibody
  • Zfp147 antibody
  • zgc:55773 antibody
  • Znf147 antibody

Protein level used designations for TRIM25

tripartite motif-containing 25 , E3 ubiquitin/ISG15 ligase TRIM25 , tripartite motif containing 25 , RING finger protein 147 , estrogen-responsive finger protein , tripartite motif protein TRIM25 , tripartite motif-containing protein 25 , ubiquitin/ISG15-conjugating enzyme TRIM25 , zinc finger protein 147 (estrogen-responsive finger protein) , zinc finger protein-147 , tripartite motif protein 25 , zinc finger protein 147

100146440 Equus caballus
393144 Danio rerio
431932 Xenopus laevis
455146 Pan troglodytes
100013883 Monodelphis domestica
100127751 Xenopus (Silurana) tropicalis
100440167 Pongo abelii
100599729 Nomascus leucogenys
7706 Homo sapiens
417401 Gallus gallus
510923 Bos taurus
491103 Canis lupus familiaris
217069 Mus musculus
494338 Rattus norvegicus
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