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Tripartite Motif Containing 37 Proteins (TRIM37)

TRIM37 encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. Additionally we are shipping TRIM37 Antibodies (55) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat TRIM37 TRIM37 360592  
TRIM37 4591 O94972
TRIM37 68729 Q6PCX9
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Top TRIM37 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details

TRIM37 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Tripartite Motif Containing 37 (TRIM37) Interaction Partners

Human Tripartite Motif Containing 37 (TRIM37) interaction partners

  1. These finding may provide insight into the understanding of TRIM37 as a novel critical factor of HCC (show FAM126A Proteins) and a candidate target for HCC (show FAM126A Proteins) treatment.

  2. results reveal TRIM37 as an oncogenic H2A ubiquitin ligase that is overexpressed in a subset of breast cancers and promotes transformation by facilitating silencing of tumour suppressors and other genes.

  3. In this study, authors demonstrate that human Trim 37 possesses anti-HIV-1 activity.

  4. The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder

  5. The TRIM37 acts as a TRIM domain-dependent E3 ubiquitin ligase and imply defective ubiquitin-dependent degradation of an as-yet-unidentified target protein in the pathogenesis of mulibrey nanism.

  6. Functional link of TRIM37 to the ubiquitin-proteosome pathway may provide novel clues to the development of metabolic syndrome.

  7. TRIM37 expression is regulated by several mechanisms: through nonsense surveillance of non-functional transcripts, as well as through 3'UTR regulatory sequences and/or naturally occurring antisense RNAs especially in testis.

  8. Novel mutations in the tumor necrosis factor (show TNF Proteins) receptor associated factor (TRAF (show TRAF1 Proteins)) domain alter the subcellular localization of TRIM37, and are associated with Wilm's tumor in a patient with mulibrey nanism.

  9. Mutation screening of the TRIM37 gene revealed that the proband had a homozygous two base pair deletion, c.1894_1895delGA, resulting in a frame-shift and a premature termination codon.

  10. inherited biallelic inactivation of TRIM37 (Mulibrey nanism) predisposes to both mesenchymal and epithelial ovarian tumors and dysregulation of TRIM37 may also be involved in the pathogenesis of sporadic fibrothecomas.

Mouse (Murine) Tripartite Motif Containing 37 (TRIM37) interaction partners

  1. Trim37 deficiency in mouse lead to infertility, prenatal-onset growth failure, infertility, cardiopathy, risk for tumors, fatty liver, and type 2 diabetes.

  2. We here show that the mouse Trim37 gene presents several alternative splice variants, including a testis-specific (show AIF1 Proteins) transcript with an additional 3' exon.

TRIM37 Protein Profile

Protein Summary

This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with TRIM37

  • tripartite motif-containing 37 (Trim37)
  • tripartite motif containing 37 (TRIM37)
  • tripartite motif-containing 37 (TRIM37)
  • 1110032A10Rik protein
  • 2810004E07Rik protein
  • AI848587 protein
  • AU043018 protein
  • mKIAA0898 protein
  • MUL protein
  • POB1 protein
  • TEF3 protein

Protein level used designations for TRIM37

E3 ubiquitin-protein ligase TRIM37 , tripartite motif protein 37 , tripartite motif-containing 37 , tripartite motif-containing 37 protein , tripartite motif-containing protein 37 , E3 ubiquitin-protein ligase TRIM37-like , tripartite motif containing 37 , RING-B-box-coiled-coil protein , mulibrey nanism protein , TRAF encompassing factor 3

GENE ID SPECIES
360592 Rattus norvegicus
417628 Gallus gallus
455163 Pan troglodytes
100010737 Monodelphis domestica
100057121 Equus caballus
100225193 Taeniopygia guttata
100403783 Callithrix jacchus
100435296 Pongo abelii
100467093 Ailuropoda melanoleuca
100518931 Sus scrofa
100550103 Meleagris gallopavo
100583751 Nomascus leucogenys
4591 Homo sapiens
480575 Canis lupus familiaris
617078 Bos taurus
68729 Mus musculus
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