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E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. Additionally we are shipping TRIM56 Proteins (3) and many more products for this protein.
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Cow (Bovine) Polyclonal TRIM56 Primary Antibody for WB - ABIN2778370
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
The C-Terminal Tail of TRIM56 Dictates Antiviral Restriction of Influenza A and B Viruses by Impeding Viral RNA Synthesis
Altogether, TRIM56 is a versatile antiviral host factor that confers resistance to yellow fever virus, dengue virus serotype 2, and human coronavirus OC43 through overlapping and distinct molecular determinants
TRIM56 is an essential component of the TLR3 (show TLR3 Antibodies) antiviral signaling pathway and reveal a novel role for TRIM56 in innate antiviral immunity.
TRIM56 is a target gene of the BACH1 (show BACH1 Antibodies) transcription factor according to ChIP-seq analysis in HEK (show EPHA3 Antibodies) 293 cells.
These data demonstrate that TRIM56 is a novel antiviral host factor that restricts pestivirus infection.
TRIM56 is an interferon (show IFNA Antibodies)-inducible E3 ubiquitin ligase (show MUL1 Antibodies) that modulates STING to confer double-stranded DNA-mediated innate immune responses.
E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA.
tripartite motif-containing 56
, tripartite motif-containing protein 56-like
, tripartite motif containing 56
, E3 ubiquitin-protein ligase TRIM56
, RING finger protein 109
, tripartite motif-containing protein 56