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anti-Tripartite Motif Containing 63 (TRIM63) Antibodies

TRIM63 encodes a member of the RING zinc finger protein family found in striated muscle and iris. Additionally we are shipping TRIM63 Proteins (7) and TRIM63 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRIM63 381485  
TRIM63 365751 Q5PQN5
TRIM63 84676 Q969Q1
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Top anti-TRIM63 Antibodies at antibodies-online.com

Showing 10 out of 146 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Goat Un-conjugated EIA, IHC (p) 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184950 (1.25µg/ml) staining of paraffin embedded Human Skeletal Muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TRIM63 Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-MuRF1/Trim63 Polyclonal Antibody, Unconjugated (ABIN741750) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image MURF1 antibody detects MURF1 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with MURF1 antibody , diluted by 1:1000. ICC/IF Image MURF1 antibody [N1], N-term detects MURF1 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: MURF1 protein stained by MURF1 antibody [N1], N-term , diluted at 1:200. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] , diluted at 1:1000. Blue: Hoechst 33342 staining. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IP, WB TRIM63 MaxPab rabbit polyclonal antibody. Western Blot analysis of TRIM63 expression in NIH/3T3. Immunoprecipitation of TRIM63 transfected lysate using anti-TRIM63 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with TRIM63 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 9 Days
$418.57
Details
Rat Goat Un-conjugated ELISA, IHC, WB   0.1 mg Log in to see 5 to 7 Days
$317.63
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Goat Un-conjugated IHC, ELISA 0.1 mg Log in to see 2 to 3 Days
$481.25
Details

TRIM63 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TRIM63 Antibodies

  1. Rat (Rattus) Polyclonal TRIM63 Primary Antibody for ELISA, IHC - ABIN250793 : Cao, Kim, Lecker: Ubiquitin-protein ligases in muscle wasting. in The international journal of biochemistry & cell biology 2005 (PubMed)
    Show all 6 references for ABIN250793

  2. Cow (Bovine) Polyclonal TRIM63 Primary Antibody for EIA, IHC (p) - ABIN782924 : de Palma, Marinelli, Pavan, Orazi: Ubiquitin ligases MuRF1 and MAFbx in human skeletal muscle atrophy. in Joint, bone, spine : revue du rhumatisme 2008 (PubMed)
    Show all 3 references for ABIN782924

  3. Human Polyclonal TRIM63 Primary Antibody for IP, WB - ABIN529746 : Meinen, Lin, Rüegg, Punga: Fatigue and muscle atrophy in a mouse model of myasthenia gravis is paralleled by loss of sarcolemmal nNOS. in PLoS ONE 2012 (PubMed)

  4. Human Polyclonal TRIM63 Primary Antibody for IHC, ELISA - ABIN184950 : Dai, Liew: A novel human striated muscle RING zinc finger protein, SMRZ, interacts with SMT3b via its RING domain. in The Journal of biological chemistry 2001 (PubMed)

  5. Human Polyclonal TRIM63 Primary Antibody for IF (p), IHC (p) - ABIN741750 : Lin, Hanson, Betik, Brennan-Speranza, Hayes, Levinger: Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2016 (PubMed)

More Antibodies against TRIM63 Interaction Partners

Mouse (Murine) Tripartite Motif Containing 63 (TRIM63) interaction partners

  1. Iron-induced skeletal muscle atrophy is suggested to involve the E3 ubiquitin ligase (show MUL1 Antibodies) mediated by the reduction of Akt (show AKT1 Antibodies)-FOXO3a (show FOXO3 Antibodies) signaling by oxidative stress.

  2. MAFbx (show FBXO32 Antibodies) mRNA expression was decreased in old mice relative to adult mice, whereas MuRF1 mRNA expression was less affected by ageing

  3. MuRF2 (show TRIM55 Antibodies) regulates PPARgamma1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet.

  4. MuRF1 directly interacts with PPARalpha (show PPARA Antibodies), mono-ubiquitinates it, and targets it for nuclear export to inhibit fatty acid oxidation in a proteasome independent manner.

  5. Increased Expression of MuRF1 Is Associated with Radiation-induced Laryngeal Muscle Atrophy.

  6. MURF1 was upregulated in cancer cachexia mice.

  7. Expression of USP19 (show USP19 Antibodies) correlates with that of MuRF1 and MAFbx/atrogin-1 (show FBXO32 Antibodies) in skeletal muscles

  8. Sunitinib is able to restrain the overactivation of STAT3 (show STAT3 Antibodies) and MuRF-1 pathways, involved in enhanced muscle protein catabolism during cancer cachexia.

  9. provide evidence that high CO2 activates skeletal muscle atrophy via AMPKalpha2 (show PRKAA2 Antibodies)-FoxO3a (show FOXO3 Antibodies)-MuRF1, which is of biological and potentially clinical significance in patients with lung diseases and hypercapnia

  10. an atrophic role for MuRF1 regulating the magnitude of right ventricular hypertrophy

Human Tripartite Motif Containing 63 (TRIM63) interaction partners

  1. Altogether, these results suggest a novel function for p63 (show RPE65 Antibodies) as a contributor to muscular atrophic processes via the regulation of multiple genes, including the muscle atrophy gene Trim63.

  2. A novel protein aggregate myopathies and cardiomyopathy resulting from combined homozygous MuRF1 null mutation and heterozygous MuRF3 (show TRIM54 Antibodies) missense mutation.

  3. Vitamin D3 might have an inhibitory effect on the expression of MAFbx (show FBXO32 Antibodies) and MuRF1 in skeletal muscle.

  4. MURF1 expression intended to be increased in the skeletal muscle of patients with malignant disease even before cancer related cachexia weight loss.

  5. TRIM63 gene expression involved in skin hyperpigmentation.

  6. Expression of USP19 (show USP19 Antibodies) correlates with that of MuRF1 and MAFbx/atrogin-1 (show FBXO32 Antibodies) in skeletal muscles

  7. Skeletal muscle atrophy induced by Angiotensin II involves activation of MuRF1 expression.

  8. These data strongly supported that rare variants in MuRF1 and MuRF2 (show TRIM55 Antibodies) are associated with higher penetrance and more severe clinical manifestations of hypertrophic cardiomyopathy.

  9. In conclusion, atrogin-1 (show FBXO32 Antibodies), MuRF1, FOXO1 (show FOXO1 Antibodies)/3A, and eIF3 (show EIF3A Antibodies)-f mRNA, and protein levels, are differentially regulated by exercise contraction mode but not WPH supplementation combined with hypertrophy-inducing training.

  10. Data reveal that Titin (show TTN Antibodies) protein is a pseudokinase with non-detectable catalytic output but is a high-affinity binding locus for MuRF1.

TRIM63 Antigen Profile

Protein Summary

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.

Gene names and symbols associated with TRIM63

  • tripartite motif-containing 55 (Trim55) antibody
  • tripartite motif-containing 63 (TRIM63) antibody
  • tripartite motif-containing 63 (trim63) antibody
  • tripartite motif containing 63 (TRIM63) antibody
  • tripartite motif-containing 63 (LOC100221817) antibody
  • tripartite motif containing 63, E3 ubiquitin protein ligase (TRIM63) antibody
  • tripartite motif containing 63, E3 ubiquitin protein ligase (Trim63) antibody
  • tripartite motif-containing 63 (Trim63) antibody
  • D830041C10Rik antibody
  • IRF antibody
  • MGC80210 antibody
  • Murf antibody
  • MuRF1 antibody
  • MURF2 antibody
  • RF1 antibody
  • Rnf28 antibody
  • Rnf29 antibody
  • rnf30 antibody
  • SMRZ antibody
  • TRIM63 antibody

Protein level used designations for TRIM63

ring finger protein 29 , tripartite motif-containing protein 55 , MURF-2 , muRF2 , muscle-specific RING finger protein 2 , tripartite motif-containing 63 , ring finger protein 30 , muscle specific ring finger protein 1 , E3 ubiquitin-protein ligase TRIM63 , muscle ring finger protein 1 , muscle specific RING finger protein-1 , e3 ubiquitin-protein ligase TRIM63-like , tripartite motif containing 63 , iris ring finger protein , muscle specific ring finger protein 2 , muscle-specific RING finger protein 1 , ring finger protein 28 , striated muscle RING zinc finger protein , tripartite motif-containing protein 63 , MURF-1 , tripartite motif protein 63

GENE ID SPECIES
381485 Mus musculus
365751 Rattus norvegicus
426754 Gallus gallus
446518 Xenopus laevis
469240 Pan troglodytes
487362 Canis lupus familiaris
528912 Bos taurus
713802 Macaca mulatta
100144767 Ovis aries
100221817 Taeniopygia guttata
100431101 Sus scrofa
100483233 Ailuropoda melanoleuca
100581509 Nomascus leucogenys
84676 Homo sapiens
140939 Rattus norvegicus
433766 Mus musculus
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