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Tripartite Motif Containing 72 Proteins (TRIM72)

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Additionally we are shipping Tripartite Motif Containing 72 Antibodies (53) and Tripartite Motif Containing 72 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRIM72 493829 Q6ZMU5
TRIM72 434246 Q1XH17
TRIM72 365377 A0JPQ4
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Top Tripartite Motif Containing 72 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,345.83
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,345.83
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,345.83
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$3,345.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TRIM72 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Tripartite Motif Containing 72 (TRIM72) Interaction Partners

Human Tripartite Motif Containing 72 (TRIM72) interaction partners

  1. MG53 is a facilitator of rapid injury repair, a mediator of cell migration, and a modulator of myofibroblast differentiation during wound healing

  2. Zn(2+) interacts with MG53 in protection against injury to the cell membrane

  3. MG53 induces FAK (show PTK2 Proteins) ubiquitination with the aid of UBE2H (show UBE2H Proteins) during skeletal myogenesis.

  4. MG53/TRIM72 protein can be directly applied as a therapeutic agent to increase membrane repair capacity of many cell types.

  5. data reveal NM-IIA as a key cytoskeleton motor protein that facilitates vesicle trafficking during MG53-mediated cell membrane repair

  6. membrane-delimited interaction between MG53 and PTRF (show PTRF Proteins) contributes to initiation of cell membrane repair

  7. MG53, annexin A1, and dysferlin localize to the t-tubule network and show enriched labeling at longitudinal tubules of the t-system in overstretch

  8. Crystal structure of PRY-SPRY domain of human TRIM72.

Mouse (Murine) Tripartite Motif Containing 72 (TRIM72) interaction partners

  1. TRIM72 directly and indirectly modulates caveolar endocytosis

  2. MG53 protein is expressed in lung tissue.

  3. Findings indicate that the manifestation of metabolic syndrome alters MG53 activity by reducing its extracellular expression in the serum and causing it to aggregate around mitochondria within striated (show NSDHL Proteins) muscle cells.

  4. MG53 is a facilitator of rapid injury repair, a mediator of cell migration, and a modulator of myofibroblast differentiation during wound healing

  5. MG53 is a vital component of reno-protection, and targeting MG53-mediated repair of renal proximal tubular epithelium cells represents a potential approach to prevention and treatment of acute kidney injury

  6. Zn(2+) interacts with MG53 in protection against injury to the cell membrane

  7. MG53-deficient hearts downregulated PPARalpha (show PPARA Proteins) target genes. MG53 plays a novel role in transcriptional upregulation of PPARalpha (show PPARA Proteins) and its target genes, resulting in lipid accumulation and lipid toxicity, thereby contributing to diabetic cardiomyopathy.

  8. These data suggest an essential role for TRIM72 in repair of alveolar epithelial cells under plasma membrane stress failure.

  9. MG53 is an ubiquitin E3 ligase that induces IRS-1 (show IRS1 Proteins) ubiquitination with the help of an E2-conjugating enzyme, UBE2H (show UBE2H Proteins).

  10. MG53 induces FAK (show PTK2 Proteins) ubiquitination with the aid of UBE2H (show UBE2H Proteins) during skeletal myogenesis.

Tripartite Motif Containing 72 (TRIM72) Protein Profile

Protein Summary

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).

Gene names and symbols associated with TRIM72

  • tripartite motif-containing 72 (TRIM72)
  • mitsugumin 53 (MG53)
  • tripartite motif containing 72 (TRIM72)
  • tripartite motif containing 72 (trim72)
  • tripartite motif-containing 72 (Trim72)
  • BC067209 protein
  • Mg53 protein
  • RGD1562778 protein
  • Trim72 protein

Protein level used designations for TRIM72

tripartite motif-containing 72 , mitsugumin-53 , tripartite motif-containing protein 72 , Mitsugumin-53 , mitsugumin 53 , mg53

GENE ID SPECIES
467960 Pan troglodytes
100008639 Oryctolagus cuniculus
493829 Homo sapiens
489927 Canis lupus familiaris
528804 Bos taurus
379612 Xenopus laevis
434246 Mus musculus
365377 Rattus norvegicus
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