anti-Tripeptidyl Peptidase II (Tpp2) Antibodies

Tpp2 encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. Additionally we are shipping Tpp2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Tpp2 7174 P29144
Tpp2 22019 Q64514
Tpp2 81815 Q64560
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Top anti-Tpp2 Antibodies at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TPP2 Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell TPP2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Chicken Un-conjugated WB   100 μL Log in to see 6 to 8 Days
$420.42
Details
Guinea Pig Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: Tripeptidyl peptidase II Antibody  - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II. Western Blot: Tripeptidyl peptidase II Antibody  - Analysis in human cell line Jurkat. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF Immunocytochemistry/Immunofluorescence: Tripeptidyl peptidase II Antibody  - Staining of human cell line RH-30 shows localization to nuclear bodies & cytosol. 100 μL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of TPP2 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i Immunohistochemical analysis of TPP2 staining in mouse lung formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the ant 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using TPP2 antibody. Immunohistochemistry of paraffin-embedded Mouse lung using TPP2 antibody at dilution of 1:100 (x400 lens). 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated IF, IHC, WB   50 μL Log in to see 7 to 9 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   50 μL Log in to see 13 to 16 Days
$313.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 11 to 12 Days
$420.00
Details

Tpp2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,

Mouse (Murine)


Rat (Rattus)


More Antibodies against Tpp2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Tripeptidyl Peptidase II (Tpp2) interaction partners

  1. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases.

  2. a systematic kinetic analysis of wild type Drosophila melanogaster TPPII and five point mutants of the double-Glu (show SLC2A1 Antibodies)-motif (E312/E343) involving natural substrates were performed.

  3. The structure suggests a model for activation of TPP II involving the relocation of a flexible loop and a repositioning of the active-site serine, coupling it to holocomplex assembly and active-site sequestration.

  4. The 150 kDa subunits of TPPII form a superstructure composed of 2 segmented & twisted (show POMT2 Antibodies) strands. Each strand is 12.5 nm in width & composed of 11 segments that enclose a central channel.

  5. the unique spindle form of the holo-complex of TPP II represents an assembly motif stabilizing a highly active state

Arabidopsis thaliana Tripeptidyl Peptidase II (Tpp2) interaction partners

  1. The purification and characterization of tripeptidyl peptidase II from Arabidopsis thaliana is reported.

Human Tripeptidyl Peptidase II (Tpp2) interaction partners

  1. Novel interactions of TPPII, p53 (show TP53 Antibodies), and SIRT7 (show SIRT7 Antibodies) presented in this study might contribute to the knowledge of the regulatory effects of these proteins on apoptotic pathways and to the understanding mechanisms of aging and lifespan regulation.

  2. TPP2 mediates many important cellular functions by controlling ERK1 (show MAPK3 Antibodies) and ERK2 (show MAPK1 Antibodies) phosphorylation.

  3. Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with TPP2 deficiency have been described in two consanguineous siblings.

  4. Study found that autosomal recessive TPP2 mutations cause recurrent infections, autoimmunity, and neurodevelopmental delay in humans.

  5. TPPII, MYBBP1A (show MYBBP1A Antibodies) and CDK2 (show CDK2 Antibodies) form a protein-protein interaction network.

  6. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases.

  7. Study showed that overexpression of Tripeptidyl peptidase II (TPP2) occurs frequently during oral carcinogenesis and might be associated with the progression of Oral Squamous Cell Carcinoma (OSCC) via Spindle Assembly Checkpoint(SAC (show ADCY10 Antibodies)) activation.

  8. obtained a 3D structure of the human TPPII

  9. Current knowledge about TPPII with a focus on structural aspects.

  10. Results suggest an important function of TPPII in the maintenance of viral growth and may have implications for anti-viral therapy.

Mouse (Murine) Tripeptidyl Peptidase II (Tpp2) interaction partners

  1. Data indicate that TPPII can regulate sperm maturation by modulating intracellular Ca(2 (show CA2 Antibodies)+) stores via the type 3 RyR (show RYR1 Antibodies).

  2. Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases.

  3. Tripeptidyl peptidase II is crucial for nucleoprotein epitope generation during major histocompatibility complex class I complex viral antigen processing both in the presence and absence of lactacystin-sensitive proteasome action.

  4. TPPII is not generally required for the production of major histocompatibility class I-restricted peptides, but presentation of some peptides can be negatively affected by TPPII.

  5. Data show that mice that were homozygous for an insertion in the Tpp2 locus were embryonic lethal and Tpp2 heterozygous mutants were lean compared with wild-type littermates, although food intake was normal.

  6. The data suggest a moderate, predominantly destructive role of TPPII in class I Ag processing.

  7. TPPII is important for maintaining normal cellular and systemic physiology, which may be relevant for potential therapeutic applications of TPPII inhibitors

  8. These results do not support a generally important role of TPPII for viability and proliferation of transformed cells or their p53 (show TP53 Antibodies)-mediated DNA damage response.

  9. These data indicate that while TPPII contributes to the trimming of peptides with very long N-terminal extensions, TPPII is not essential for generating most MHC class I-presented peptides or for stimulating CTL responses to several Ags (show GLA Antibodies) in vivo.

Tpp2 Antigen Profile

Protein Summary

This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase\; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.

Gene names and symbols associated with Tpp2

  • tripeptidyl peptidase 2 (TPP2) antibody
  • tripeptidyl peptidase II (Tpp2) antibody
  • tripeptidyl-peptidase II (TppII) antibody
  • tripeptidyl peptidase 2 (Tpp2) antibody
  • tripeptidyl peptidase 2 L homeolog (tpp2.L) antibody
  • tripeptidyl peptidase ii (TPP2) antibody
  • tripeptidyl-peptidase 2 (LOC5572106) antibody
  • tripeptidyl peptidase 2 (tpp2) antibody
  • anon-WO0118547.127 antibody
  • CG3991 antibody
  • DKFZp468E2313 antibody
  • Dmel\\CG3991 antibody
  • dTPPII antibody
  • dTPP II antibody
  • l(2)k14301 antibody
  • MGC83244 antibody
  • T13K14.10 antibody
  • T13K14_10 antibody
  • TPP-2 antibody
  • TPP2 antibody
  • TPPII antibody
  • TPP II antibody
  • tripeptidyl peptidase ii antibody

Protein level used designations for Tpp2

TPP-II , tripeptidyl aminopeptidase , tripeptidyl-peptidase 2 , tripeptidyl-peptidase II , CG3991-PA , CG3991-PD , TppII-PA , TppII-PD , Tripeptidyl-peptidase II , tripeptidyl peptidase II , tripeptidylpeptidase II , tripeptidyl peptidase ii

GENE ID SPECIES
7174 Homo sapiens
22019 Mus musculus
36444 Drosophila melanogaster
81815 Rattus norvegicus
428020 Gallus gallus
443806 Xenopus laevis
526052 Bos taurus
827833 Arabidopsis thaliana
5572106 Aedes aegypti
100101674 Xenopus (Silurana) tropicalis
100172493 Pongo abelii
100359134 Oryctolagus cuniculus
100552517 Anolis carolinensis
100720822 Cavia porcellus
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