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Troponin I Type 3 (Cardiac) Proteins (TNNI3)

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. Additionally we are shipping Troponin I Type 3 (Cardiac) Antibodies (1006) and Troponin I Type 3 (Cardiac) Kits (107) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNNI3 7137 P19429
TNNI3 29248 P23693
TNNI3 21954 P48787
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Top Troponin I Type 3 (Cardiac) Proteins at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Troponin I Type 3 (Cardiac) (TNNI3) protein 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Baculovirus Human His tag 50 μg Log in to see 13 to 16 Days
$1,353.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,387.00
Details
Yeast Horse His tag   1 mg Log in to see 56 to 66 Days
$2,498.83
Details

TNNI3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Rat (Rattus) , ,

Mouse (Murine)

Top referenced Troponin I Type 3 (Cardiac) Proteins

  1. Human TNNI3 Protein expressed in Escherichia coli (E. coli) - ABIN1047784 : Hunkeler, Kullman, Murphy: Troponin I isoform expression in human heart. in Circulation research 1991 (PubMed)
    Show all 2 references for ABIN1047784

More Proteins for Troponin I Type 3 (Cardiac) (TNNI3) Interaction Partners

Human Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. Compromised interactions of K206I with actin and hcTnC may lead to impaired relaxation and HCM.

  2. hsTnI at the time of presentation followed by early advanced coronary CTA (show PCYT1A Proteins) assessment improves the risk stratification and diagnostic accuracy for acute coronary syndromes.

  3. These findings showed that a double heterozygous mutation in the TNNI3 gene is involved in the pathogenesis of hypertrophic cardiomyopathy via haploinsufficiency.

  4. The incidence of adverse cardiovascular events was significantly higher in patients with troponin elevation after carotid endarterectomy, which was mainly attributable to silent non-ST segment elevation MIs (show AMH Proteins) that occurred in the early post-operative phase.

  5. Four novel missense variants were identified in TNNI3.

  6. Letter/Case Report: acute decompensated heart failure with troponin I elevation in hereditary hemochromatosis (show HFE Proteins).

  7. In this pilot study, the addition of CACS to hsTnI improves the identification of low-risk subjects in whom CTA (show PCYT1A Proteins) might be avoided.

  8. Exclusion of acute myocardial infarction 2h after presentation in emergency patients with possible acute coronary syndrome can be achieved using hs-cTnT or hs-cTnI assays.

  9. Troponin C (TnC) and the N-terminal helix of Troponin I (TnI N-helix), which occurs in vivo during muscle contraction.

  10. Hybrid coronary revascularization is associated with lower postoperative cTn (show CALCA Proteins) release, compared with off-pump coronary artery bypass surgery.

Pig (Porcine) Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

  2. hFABP (show FABP3 Proteins) rises faster and correlates better with infarct size and no-reflow than hsTnI in myocardial infarction + reperfusion when measured early after reperfusion.

  3. analysis of expression profiling of porcine troponin I family in three different types of muscles during development

Horse (Equine) Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. Cardiac ANP was increased in horses with mitral regurgitation (MR) and cardiac troponin levels were low in healthy and MR affected horses.

Mouse (Murine) Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. The difference in myosin regulatory light chain phosphorylation between the ventricles of R21C(+/+) in cardiac troponin I mice likely contributes to observed differences in contractile force and the lower tension monitored in the LV of HCM mice

  2. troponin I phosphorylation specifically alters the Ca(2 (show CA2 Proteins)+) sensitivity of isometric tension and the time course of relaxation in cardiac muscle myofibrils

  3. Combined troponin I Ser (show SIGLEC1 Proteins)-150 and Ser (show SIGLEC1 Proteins)-23/24 phosphorylation sustains thin filament Ca(2 (show CA2 Proteins)+) sensitivity playing an adaptive role to preserve contraction during acidic ischemia.

  4. these results indicate that the inability to enhance myofilament relaxation through cTnI phosphorylation predisposes the heart to abnormal diastolic function, reduced accessibility of cardiac reserves, dysautonomia, and hypertrophy.

  5. Dominant negative TnI-TnT interface mutation decreases the binding affinity of cTnI for TnT, causes early ventricular remodeling, and blunts the beta-adrenergic response of cardiac myocytes.

  6. R193H and R205H mutation increase the binding affinity of Troponin I for Troponin T and Troponin C.

  7. Conclude that dilated cardiomyopathy-causing mutations in thin filament proteins abolish the relationship between myofilament Ca(2+) sensitivity and troponin I phosphorylation by PKA.

  8. The pattern of cTnI post-translational modification depends on sex and hypertrophic cardiomyopathy genotype.

  9. A new functional and pathological role of amino acid modifications in the N-terminal acidic domain of cardiac TnI (show TNNI2 Proteins) has been found that is modified by phosphorylations at TnI (show TNNI2 Proteins)(S23 (show RPS23 Proteins)/S24 (show RPS24 Proteins)).

  10. Data show that cardiac TnI (show TNNI2 Proteins) gene transition and the alternatively spliced cardiac TnT isoform switching occur in postnatal pulmonary vein.

Cow (Bovine) Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. An Ala8Val mutation enhances the effect of cardiac troponin I pseudophosphorylation on the rate of dissociation of calcium from reconstituted thin filaments.

  2. Serum cardiac troponin I cannot be used to distinguish cattle with pericarditis from cattle with other primary cardiac diseases or noncardiac, intrathoracic disorders.

Troponin I Type 3 (Cardiac) (TNNI3) Protein Profile

Protein Summary

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit\; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Gene names and symbols associated with TNNI3

  • troponin I type 3 (cardiac) (TNNI3)
  • cardiac troponin I (tnni3)
  • troponin I type 3 (cardiac) (Tnni3)
  • troponin I, cardiac 3 (Tnni3)
  • troponin I, cardiac muscle-like (LOC511094)
  • CMD1FF protein
  • CMD2A protein
  • CMH7 protein
  • cTNI protein
  • RCM1 protein
  • Tn1 protein
  • TnI protein
  • TNNC1 protein
  • TNNI3 protein

Protein level used designations for TNNI3

troponin I type 3 (cardiac) , troponin I, cardiac muscle , troponin IC , cardiac troponin I , troponin 1, type 3

GENE ID SPECIES
698470 Macaca mulatta
397803 Xenopus laevis
396428 Gallus gallus
7137 Homo sapiens
403566 Canis lupus familiaris
493744 Felis catus
100049696 Sus scrofa
29248 Rattus norvegicus
100034065 Equus caballus
101121961 Ovis aries
21954 Mus musculus
511094 Bos taurus
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