anti-Troponin I Type 3 (Cardiac) (TNNI3) Antibodies

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. Additionally we are shipping Troponin I Type 3 (Cardiac) Kits (107) and Troponin I Type 3 (Cardiac) Proteins (40) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNNI3 7137 P19429
TNNI3 29248 P23693
TNNI3 21954 P48787
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Top anti-Troponin I Type 3 (Cardiac) Antibodies at antibodies-online.com

Showing 10 out of 967 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rabbit heart labeled with Anti CTn1/Troponin I/TNNC1 Polyclonal Antibody,Unconjugated (ABIN728308) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded mouse heart tissue with Anti-CTn1/Troponin I/TNNC1 Polyclonal Antibody, Unconjugated (ABIN728308) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Amphibian Mouse Un-conjugated EIA, WB   1 mg Log in to see 6 to 8 Days
$621.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Tnni3 Antibody Titration: 1.0 ug/ml Positive Control: Rat Pancreas 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Mouse Un-conjugated IA, IHC (p), IP, IHC, ELISA, WB Flow Cytometry: Troponin I Type 3 (cardiac) Antibody (19C7) [ABIN258010] - FACS analysis of Troponin I Type 3 in differentiated ESC cultures using anti-Troponin I Type 3 (cardiac) antibody. Image from verified customer review. Immunocytochemistry: Troponin I Type 3 (cardiac) Antibody (19C7) [ABIN258010] - Analysis of murine early primitive ectoderm-like cells, staining Cardiac Troponin I. 0.2 mg Log in to see 7 to 9 Days
$317.63
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Cow Mouse Un-conjugated EIA, WB   0.25 mg Log in to see 6 to 8 Days
$467.50
Details
Human Goat Un-conjugated EIA   0.2 mg Log in to see 6 to 8 Days
$357.50
Details
Chicken Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details

TNNI3 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Troponin I Type 3 (Cardiac) Antibodies

  1. Human Polyclonal TNNI3 Primary Antibody for IF (p), IHC (p) - ABIN728308 : Liu, Li, Sun, Li, Du, Sun, Cao, Li, Jia, Wang, Chang, Yu, Wang, Peng: The use of antibody modified liposomes loaded with AMO-1 to deliver oligonucleotides to ischemic myocardium for arrhythmia therapy. in Biomaterials 2014 (PubMed)
    Show all 6 references for 728308

  2. Human Polyclonal TNNI3 Primary Antibody for EIA - ABIN318833 : Takeda: Crystal structure of troponin and the molecular mechanism of muscle regulation. in Journal of electron microscopy 2005 (PubMed)
    Show all 2 references for 318833

  3. Cow (Bovine) Monoclonal TNNI3 Primary Antibody for IA, IHC (p) - ABIN258010 : Selimoglu, Kasap, Akpinar, Karadenizli: Overcoming difficulties on synthesis of cardiac troponin-I. in Preparative biochemistry & biotechnology 2016 (PubMed)
    Show all 2 references for 258010

  4. Amphibian Monoclonal TNNI3 Primary Antibody for EIA, WB - ABIN272322 : Laube, Heister, Scholz, Borchardt, Braun: Re-programming of newt cardiomyocytes is induced by tissue regeneration. in Journal of cell science 2006 (PubMed)

  5. Cow (Bovine) Polyclonal TNNI3 Primary Antibody for IHC, WB - ABIN2776782 : Bos, Theis, Tajik, Gersh, Ommen, Ackerman: Relationship between sex, shape, and substrate in hypertrophic cardiomyopathy. in American heart journal 2008 (PubMed)

  6. Cow (Bovine) Monoclonal TNNI3 Primary Antibody for EIA, WB - ABIN118970 : Marian, Zhao, Seta, Roberts, Yu: Expression of a mutant (Arg92Gln) human cardiac troponin T, known to cause hypertrophic cardiomyopathy, impairs adult cardiac myocyte contractility. in Circulation research 1997 (PubMed)

More Antibodies against Troponin I Type 3 (Cardiac) Interaction Partners

Human Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. Study showed that in patients who underwent liver transplantation elevation of preoperative high-sensitivity cardiac troponin I level was associated with 1-year mortality and 30-day mortality.

  2. Serial measurement of troponin I revealed a persistent elevation in patients with diabetes mellitus type 2.

  3. Plasma troponin C1 (cTnI) is biomarker of choice for diagnosing acute myocardial infarction (AMI (show CFD Antibodies)) because of its high specificity as biomarker for damage to myocardial tissue. Data suggest the "best cut-off" for plasma cTnI is 0.014 micrograms/L in AMI (show CFD Antibodies). These studies were conducted in emergency department of a university hospital in Italy using point-of-care testing in patients presenting with chest pain, ages 18-101.

  4. NT-proBNP and hs-cTnI levels were higher in systemic sclerosis patients than controls. Both NT-proBNP and hs-cTnI were associated with the presence of echocardiographic abnormalities.

  5. value of cTnI level assessed 24 hours post-surgery was a reliable predictor of death following liver transplantation with optimal cut-off value of 0.215 ng/mL. The surgery time was the most important predictor of cTnI elevation.

  6. cTnI levels are common in Fabry disease patients, reflecting cardiac involvement.

  7. Report novel troponin I rule-out value below the upper reference limit for acute myocardial infarction.

  8. cTnI determined in hemodynamically stable patients with suspected AMI (show CFD Antibodies) and wide QRS (show QARS Antibodies) complex using optimized diagnostic thresholds improves rule-in and rule-out with respect to presence of a significant obstructive CAD (show CAD Antibodies)

  9. 83 preterm infants with Bronchopulmonary dysplasia born <28-wk gestation and still inpatients at 36-wk corrected age received an echocardiogram and blood tests of B-type natriuretic peptide (BNP (show BNP Antibodies)), troponin I, and YKL-40 (show CHI3L1 Antibodies).

  10. Serum cardiac troponin I was increased in septic patients with myocardial depression compared to those without myocardial depression.

Pig (Porcine) Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

  2. hFABP (show FABP3 Antibodies) rises faster and correlates better with infarct size and no-reflow than hsTnI in myocardial infarction + reperfusion when measured early after reperfusion.

  3. analysis of expression profiling of porcine troponin I family in three different types of muscles during development

Horse (Equine) Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. Cardiac ANP was increased in horses with mitral regurgitation (MR) and cardiac troponin levels were low in healthy and MR affected horses.

Mouse (Murine) Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. Hyperphosphorylation of this serine199 in cTnI C terminus impacts heart function by depressing diastolic function at baseline and limiting systolic reserve under physiological stresses. Paradoxically, it preserves heart function after ischemia/reperfusion injury, potentially by decreasing proteolysis of cTnI.

  2. The contributions of cardiac myosin binding protein C and troponin I phosphorylation to beta-adrenergic enhancement of in vivo cardiac function

  3. The difference in myosin regulatory light chain phosphorylation between the ventricles of R21C(+/+) in cardiac troponin I mice likely contributes to observed differences in contractile force and the lower tension monitored in the LV of HCM mice

  4. troponin I phosphorylation specifically alters the Ca(2 (show CA2 Antibodies)+) sensitivity of isometric tension and the time course of relaxation in cardiac muscle myofibrils

  5. Combined troponin I Ser (show SIGLEC1 Antibodies)-150 and Ser (show SIGLEC1 Antibodies)-23/24 phosphorylation sustains thin filament Ca(2 (show CA2 Antibodies)+) sensitivity playing an adaptive role to preserve contraction during acidic ischemia.

  6. these results indicate that the inability to enhance myofilament relaxation through cTnI phosphorylation predisposes the heart to abnormal diastolic function, reduced accessibility of cardiac reserves, dysautonomia, and hypertrophy.

  7. Dominant negative TnI-TnT interface mutation decreases the binding affinity of cTnI for TnT, causes early ventricular remodeling, and blunts the beta-adrenergic response of cardiac myocytes.

  8. R193H and R205H mutation increase the binding affinity of Troponin I for Troponin T and Troponin C.

  9. Conclude that dilated cardiomyopathy-causing mutations in thin filament proteins abolish the relationship between myofilament Ca(2+) sensitivity and troponin I phosphorylation by PKA.

  10. The pattern of cTnI post-translational modification depends on sex and hypertrophic cardiomyopathy genotype.

Cow (Bovine) Troponin I Type 3 (Cardiac) (TNNI3) interaction partners

  1. An Ala8Val mutation enhances the effect of cardiac troponin I pseudophosphorylation on the rate of dissociation of calcium from reconstituted thin filaments.

  2. Serum cardiac troponin I cannot be used to distinguish cattle with pericarditis from cattle with other primary cardiac diseases or noncardiac, intrathoracic disorders.

Troponin I Type 3 (Cardiac) (TNNI3) Antigen Profile

Protein Summary

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit\; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Gene names and symbols associated with TNNI3

  • troponin I type 3 (cardiac) (TNNI3) antibody
  • cardiac troponin I (tnni3) antibody
  • troponin I type 3 (cardiac) (Tnni3) antibody
  • troponin I, cardiac 3 (Tnni3) antibody
  • troponin I, cardiac muscle-like (LOC511094) antibody
  • CMD1FF antibody
  • CMD2A antibody
  • CMH7 antibody
  • cTNI antibody
  • RCM1 antibody
  • Tn1 antibody
  • TnI antibody
  • TNNC1 antibody
  • TNNI3 antibody

Protein level used designations for TNNI3

troponin I type 3 (cardiac) , troponin I, cardiac muscle , troponin IC , cardiac troponin I , troponin 1, type 3

GENE ID SPECIES
698470 Macaca mulatta
397803 Xenopus laevis
396428 Gallus gallus
7137 Homo sapiens
403566 Canis lupus familiaris
493744 Felis catus
100049696 Sus scrofa
29248 Rattus norvegicus
100034065 Equus caballus
101121961 Ovis aries
21954 Mus musculus
511094 Bos taurus
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