You are viewing an incomplete version of our website. Please click to reload the website as full version.

Troponin T, Slow Skeletal Muscle Proteins (TNNI1)

TNNI1 encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. Additionally we are shipping TNNI1 Antibodies (28) and TNNI1 Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNNI1 7138 P13805
TNNI1 171409 Q7TNB2
TNNI1 21955 O88346
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top TNNI1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,674.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,682.17
Details

TNNI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Rat (Rattus)

Mouse (Murine)

More Proteins for Troponin T, Slow Skeletal Muscle (TNNI1) Interaction Partners

Zebrafish Troponin T, Slow Skeletal Muscle (TNNI1) interaction partners

  1. Complete loss of troponin T3a, T3b and T2c activities leads to loss of sarcomere structure.

  2. Tnnt1, Tnnt2 (show TNNT2 Proteins), and Tnnt3b were conserved in the central tropomyosin (show TPM2 Proteins)- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 and Tnnt2 (show TNNT2 Proteins), but not Tnnt3b.

Human Troponin T, Slow Skeletal Muscle (TNNI1) interaction partners

  1. Three homologous genes have evolved in vertebrates to encode three muscle type-specific TnT isoforms: TNNT1 for slow skeletal muscle TnT, TNNT2 for cardiac muscle TnT, and TNNT3 for fast skeletal muscle TnT.

  2. Nemaline body myopathy Palestinian patients were found to have a novel mutation in troponin T1.

  3. troponin T and creatinine kinase isoenzyme (CK-MB) have roles in combined renal and myocardial injuries in asphyxiated infants

  4. Biopsy-proven acute and viral myocarditis is associated with elevated concentrations of hs-TnT.

  5. Troponin T1 blood levels had a positive association with increased risk for hypertrophic cardiomyopathy.

  6. TNNT1 DNA methylation (show HELLS Proteins) levels were positively correlated with mean HDL (show HSD11B1 Proteins) particle size, HDL (show HSD11B1 Proteins)-phospholipid, HDL (show HSD11B1 Proteins)-apolipoprotein AI (show APOA1 Proteins), HDL (show HSD11B1 Proteins)-C and TNNT1 expression levels.

  7. Human slow skeletal troponin T (HSSTnT) isoforms, despite being homologues of cardiac TnT may display distinct functional properties in muscle regulation.

  8. analysis of parameters of oxygen-dependent metabolism of neutrophils by NBT test and levels of vWF antigen in the serum can be used for predicting the risk of unfavorable outcome in patients with ACS and normal troponin T

  9. In heart failure patients with normal ejection fraction, highly sensitive troponin T and heart fatty acid binding protein (show FABP3 Proteins) are elevated independent of coronary artery disease.

  10. baseline cTnT (show TNNT2 Proteins) levels are higher in patients with MPI (show MPI Proteins) evidence of reversible myocardial ischaemia than those without reversible ischaemia

Mouse (Murine) Troponin T, Slow Skeletal Muscle (TNNI1) interaction partners

  1. Mouse tumor endothelial cells express troponin T.

  2. demonstrated that ssTnT deficiency resulted in significantly decreased levels of other slow fibre-specific myofilament proteins whereas fast fibre-specific myofilament proteins were increased correspondingly

  3. the induction of Tnnt1 gene expression in adult mouse brains by ketamine may illustrate the genes involved in the metabolic syndromes observed in neuropsychiatric disorders

  4. Data show that cardiac expression of slow skeletal troponin T (Tnnt1) strictly depends on the physical interaction between GATA4-FOG2 in the myocardium of both atria and ventricles.

TNNI1 Protein Profile

Protein Summary

This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TNNI1

  • troponin I, skeletal, slow a (tnni1a)
  • troponin I type 1 (skeletal, slow) (tnni1)
  • troponin I type 1 (skeletal, slow) (TNNI1)
  • troponin I, skeletal, slow b (tnni1b)
  • troponin I, slow skeletal muscle (tnni1)
  • troponin T type 1 (skeletal, slow) (tnnt1)
  • troponin T type 1 (skeletal, slow) (TNNT1)
  • troponin T type 1 (skeletal, slow) (Tnnt1)
  • troponin T1, skeletal, slow (tnnt1)
  • troponin T1, skeletal, slow (Tnnt1)
  • ANM protein
  • AW146156 protein
  • cb328 protein
  • Fang2 protein
  • MGC75706 protein
  • NEM5 protein
  • sb:cb328 protein
  • si:dz182n13.3 protein
  • ssTnT protein
  • stnt protein
  • TNNI1 protein
  • Tnnt protein
  • Tnt protein
  • tnTs protein
  • zgc:86847 protein
  • zgc:103458 protein

Protein level used designations for TNNI1

troponin I type 1 (skeletal, slow) , troponin I, skeletal, slow 1 , troponin I, skeletal, slow , TnnI-HC , nemaline myopathy type 5 , slow skeletal muscle troponin T , troponin T, slow skeletal muscle , troponin-T1, skeletal, slow , sTnT , tnTs , troponin T slow type isoform sTnT1 , troponin T1, skeletal, slow , skeletal muscle slow-twitch TnT

GENE ID SPECIES
368778 Danio rerio
394556 Xenopus (Silurana) tropicalis
469636 Pan troglodytes
494070 Danio rerio
100196284 Salmo salar
444636 Xenopus laevis
7138 Homo sapiens
396579 Sus scrofa
282095 Bos taurus
171409 Rattus norvegicus
353248 Danio rerio
21955 Mus musculus
Selected quality suppliers for TNNI1 Proteins (TNNI1)
Did you look for something else?