You are viewing an incomplete version of our website. Please click to reload the website as full version.

Troponin T2, Cardiac Proteins (TNNT2)

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Additionally we are shipping Cardiac Troponin T2 Antibodies (362) and Cardiac Troponin T2 Kits (71) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNNT2 7139 P45379
TNNT2 24837 P50753
TNNT2 21956 P50752
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Cardiac Troponin T2 Proteins at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$827.20
Details
HOST_Escherichia coli (E. coli) Wild boar His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$862.40
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,746.33
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,753.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,790.33
Details

TNNT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus) , ,
,
Mouse (Murine)
,

More Proteins for Troponin T2, Cardiac (TNNT2) Interaction Partners

Human Troponin T2, Cardiac (TNNT2) interaction partners

  1. sensitivity and specificity of cardiac specific troponin T levels in detecting cardiac damage are much higher according to telecardiography and electrocardiography

  2. since hs-cTnT levels of non-AMI patients can be over the diagnostic cut-off value, further studies are necessary to define clinically applicable cut-off values of hs-cTnT

  3. Data indicate that cardiac troponin T (cTn (show CALCA Proteins)) timing was comparable between the urban university maximum care and the rural regional primary care facility.

  4. Troponin T velocity can be used for early risk stratification of patients with increased risk for cardiac mortality.

  5. hs-cTnT may be a more useful marker than cTnI (show TNNI3 Proteins) to detect peri (show PLIN1 Proteins)-operative myocardial apoptosis and injury during coronary artery bypass grafting with cardiopulmonary bypass.

  6. Hs-cTnT was independently associated with LV dysfunction and LV hypertrophy assessed with MPI (show MPI Proteins) in newly diagnosed hypertensive patients.

  7. In patients with acute ischemic stroke, troponin T levels were elevated compared to controls.

  8. In patients with stable angina, the presence and extent of coronary atherosclerosis is related with circulating levels of hs-cTnT, also in the absence of ischemia, suggesting an ischemia-independent mechanism of hs-cTnT release.

  9. Increased hs-cTnT levels occur in 30% of female patients after TOF (show FEZF2 Proteins) repair, and are associated with greater RV volumes and worse RV EF.

  10. Three homologous genes have evolved in vertebrates to encode three muscle type-specific TnT isoforms: TNNT1 for slow skeletal muscle TnT, TNNT2 for cardiac muscle TnT, and TNNT3 for fast skeletal muscle TnT.

Pig (Porcine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Cow (Bovine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. Significant changes in thin filament Ca2 (show CA2 Proteins)+-sensitivity, structure and kinetics are brought about through PKC phosphorylation of cardiac troponin T.

  2. The mu-calpain-mediated proteolytic modification of TnT by removing the NH2-terminal variable region of TnT may act as an acute mechanism to adjust muscle contractility under stress conditions.

Rabbit Troponin T2, Cardiac (TNNT2) interaction partners

  1. Substituting smooth muscle caldesmon for skeletal muscle troponin produces a similar decrease and re-increase in fluorescence, but the apparent rate constant for the increase is >10 times that observed with troponin.

  2. In ischemic myocardium, the expression of cTnT showed prominent focal or flaky depletion in myocardial cytoplasm with no expression detected in interstitium.

Mouse (Murine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. MBPC and troponin-I phosphorylation modulate myofilament length-dependent activation

  2. Data indicate that the troponin T Tnnt2(MerCreMer/+) mouse model also provides a useful tool to trace myocardial lineage during development.

  3. TnT (show TNNI1 Proteins) mutation F72L leads to contractile changes that are linked to dilated cardiomyopathy in the presence of MYH6 (show MYH6 Proteins) and hypertrophic cardiomyopathy in the presence of MYH7 (show MYH7 Proteins).

  4. TNT increases slightly during low flux-hemodialysis. High-flux hemodialysis eliminates the biomarker and can mask increases caused by cardiac disease.

  5. Dominant negative TnI-TnT interface mutation decreases the binding affinity of cTnI for TnT, causes early ventricular remodeling, and blunts the beta-adrenergic response of cardiac myocytes.

  6. Cardiac muscle activation blunted by a mutation to the regulatory component, troponin T.

  7. Study is the first to show that the interplay between the N terminus of cTnT and the overlapping ends of contiguous Tm effectuates different states of Tm on the actin filament.

  8. We conclude that the observed clinical severity of the cTnT Delta160E mutation is caused by a combination of direct sarcomeric disruption coupled to a profound dysregulation of Ca(2 (show CA2 Proteins)+) homeostasis

  9. Report two distinct functional regions within the N-terminus of cTnT with divergent roles in mediating cardiac contractile activation.

  10. Data show that cardiac TnI (show TNNI2 Proteins) gene transition and the alternatively spliced cardiac TnT isoform switching occur in postnatal pulmonary vein.

Zebrafish Troponin T2, Cardiac (TNNT2) interaction partners

  1. Data showed that CXCR4a was significantly more highly expressed in tnnt2 knocked down mutant at 48 and 60 hpf than controls.

  2. We show that the zebrafish silent heart (sih) mutation affects the gene tnnt2.

  3. Tnnt1 (show TNNI1 Proteins), Tnnt2, and Tnnt3b were conserved in the central tropomyosin (show TPM2 Proteins)- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 (show TNNI1 Proteins) and Tnnt2, but not Tnnt3b.

Cardiac Troponin T2 (TNNT2) Protein Profile

Protein Summary

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Gene names and symbols associated with Troponin T2, Cardiac Proteins (TNNT2)

  • troponin T type 2 (cardiac) (TNNT2)
  • troponin T2, cardiac (Tnnt2)
  • troponin T type 2 (cardiac) (Tnnt2)
  • troponin T type 2 (cardiac) (tnnt2)
  • troponin T2a, cardiac (tnnt2a)
  • CMH2 protein
  • CMPD2 protein
  • CT3 protein
  • cTnT protein
  • Ctt protein
  • CTTG protein
  • LVNC6 protein
  • RATCTTG protein
  • RCM3 protein
  • tnnt2 protein
  • Tnnt3 protein
  • Tnt protein
  • TnTC protein

Protein level used designations for Troponin T2, Cardiac Proteins (TNNT2)

troponin T, cardiac muscle , troponin T2, cardiac , cardiac troponin 2 , cardiac troponin T , troponin T type 2, cardiac , cardiomyopathy, dilated 1D (autosomal dominant) , cardiomyopathy, hypertrophic 2 , Troponin T cardiac , cTnT , cardiac muscle troponin T , cardiac troponin T2 , tnTc , cardiac troponin T form I , tnTC , troponin T, cardiac muscle isoforms , Troponin T, cardiac muscle , troponin T cardiac isoform , cardiac TnT , sih , silent heart

GENE ID SPECIES
493940 Felis catus
100379561 Cavia porcellus
403532 Canis lupus familiaris
7139 Homo sapiens
24837 Rattus norvegicus
398518 Xenopus laevis
396433 Gallus gallus
100622450 Sus scrofa
286816 Bos taurus
100009428 Oryctolagus cuniculus
21956 Mus musculus
58071 Danio rerio
Selected quality suppliers for Cardiac Troponin T2 Proteins (TNNT2)
Did you look for something else?