anti-Tryptase beta 2 (Gene/pseudogene) (TPSB2) Antibodies

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse TPSB2 TPSB2 17229  
Anti-Rat TPSB2 TPSB2 29268 P50343
Anti-Human TPSB2 TPSB2 64499 P20231
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

More Antibodies against TPSB2 Interaction Partners

Mouse (Murine) Tryptase beta 2 (Gene/pseudogene) (TPSB2) interaction partners

  1. Inflammatory Th2 responses can develop independently of MCP-6, whereas MCP-6 plays a key role in the development of airway hyperresponsiveness.

  2. Tryptase (show TPSAB1 Antibodies)-beta was capable of inducing pelvic pain and was increased in experimental autoimmune prostatitis.

  3. mast cell tryptase, a serglycin proteoglycan (show SRGN Antibodies)-dependent secretory granule protease, has a role in proteolytic histone modification

  4. Trypase can promote atherosclerotic plaque haemorrhage by promoting angiogenesis and regulating the balance of PAI-1 (show SERPINE1 Antibodies) and tPA (show PLAT Antibodies).

  5. This study demonstrates for the first time that an mast cell-restricted tetramer-forming tryptase (show TPSAB1 Antibodies) has a prominent adverse role in experimental chronic obstructive pulmonary disease

  6. this study indicates that mast cells may be a source of TGF-beta (show TGFB1 Antibodies) production after cigarette smoke exposure and that in turn TGF-beta (show TGFB1 Antibodies) may change the tryptase (show TPSAB1 Antibodies) expression in mast cells.

  7. MCP6 actively depletes the local environment of IL-6 (show IL6 Antibodies) to maintain tolerance in mice.

  8. MCP-6 (but not MCP-7 (show TPSAB1 Antibodies)) is an essential mast cell-restricted mediator in chemically induced colitis and acts upstream of many of the factors implicated in inflammatory bowel disease.

  9. mast cell mMCP-4, -5, and -6 (chymase (show CMA1 Antibodies) and tryptase (show TPSAB1 Antibodies)) participate in the acute inflammation and remodeling process of viral myocarditis.

  10. Tryptase (show TPSAB1 Antibodies) contained in the neurons and in the endothelial cells of the mdx (show DMD Antibodies) mouse brain may be involved in the regulation of angiogenesis taking place in mdx (show DMD Antibodies) mouse.

Human Tryptase beta 2 (Gene/pseudogene) (TPSB2) interaction partners

  1. These observations indicate that betaII-tryptase (show TPSAB1 Antibodies) activity is post-translationally regulated by an allosteric disulfide bond.

  2. Results indicate a key role for heparin in the activation of human betaI- and beta2-tryptase (show TPSAB1 Antibodies).

  3. The disease severity and plasma tryptase (show TPSAB1 Antibodies) levels were not affected by the number of alpha or beta tryptase (show TPSAB1 Antibodies) alleles in mastocytosis patients.

  4. Strong linkage of TPSAB1 (show TPSAB1 Antibodies) and TPSB2 and pairing of deficiency alleles with functional alleles in observed haplotypes protect human subjects from "knockout" genomes and indeed from inheritance of fewer than 2 active alleles.

TPSB2 Antigen Profile

Protein Summary

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Gene names and symbols associated with TPSB2

  • tryptase beta 2 (Tpsb2) antibody
  • tryptase beta 2 (gene/pseudogene) (TPSB2) antibody
  • AV011504 antibody
  • Mcp-6 antibody
  • Mcp6 antibody
  • Mcpt6 antibody
  • MMCP-6 antibody
  • TPS2 antibody
  • tryptaseB antibody
  • tryptaseC antibody

Protein level used designations for TPSB2

mast cell protease 6 , tryptase beta-2 , tryptase-2 , rMCP-6 , mast cell tryptase beta II , mast cell tryptase beta III

17229 Mus musculus
29268 Rattus norvegicus
64499 Homo sapiens
Did you look for something else?