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anti-Tryptophan 2,3-Dioxygenase (TDO2) Antibodies

TDO2 encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Additionally we are shipping Tryptophan 2,3-Dioxygenase Kits (28) and Tryptophan 2,3-Dioxygenase Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TDO2 6999 P48775
TDO2 56720 P48776
Anti-Rat TDO2 TDO2 64206 P21643
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Top anti-Tryptophan 2,3-Dioxygenase Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-TDO2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged TDO2 is approximately 10 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2. Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-TDO2 mouse monoclonal antibody. (ABIN2455754) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Rabbit Un-conjugated WB TDO2 Antibody (N-term) (ABIN658265) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the TDO2 antibody detected the TDO2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB Western Blot analysis of TDO2 expression in transfected 293T cell line by TDO2 MaxPab polyclonal antibody.Lane 1: TDO2 transfected lysate(47.90 KDa).Lane 2: Non-transfected lysate. TDO2 MaxPab rabbit polyclonal antibody. Western Blot analysis of TDO2 expression in Jurkat. 100 μg Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of TDO2 expression in transfected 293T cell line by TDO2 MaxPab polyclonal antibody.Lane 1: TDO2 transfected lysate(44.66 KDa).Lane 2: Non-transfected lysate. TDO2 MaxPab polyclonal antibody. Western Blot analysis of TDO2 expression in human liver. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

TDO2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)


Top referenced anti-Tryptophan 2,3-Dioxygenase Antibodies

  1. Human Monoclonal TDO2 Primary Antibody for ELISA - ABIN394955 : Roeske, Ludwig, Neuhoff, Becker, Bartling, Bruder, Brockschmidt, Warnke, Remschmidt, Hoffmann, Müller-Myhsok, Nöthen, Schulte-Körne: First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children. in Molecular psychiatry 2010 (PubMed)
    Show all 5 references for ABIN394955

  2. Human Polyclonal TDO2 Primary Antibody for WB - ABIN520811 : Ohira, Hagihara, Toyama, Takao, Kanai, Funakoshi, Nakamura, Miyakawa: Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus. in Molecular brain 2010 (PubMed)

  3. Human Polyclonal TDO2 Primary Antibody for WB - ABIN948536 : Xiao, Li, Jones-Brando, Yolken: Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains. in Journal of neural transmission (Vienna, Austria : 1996) 2013 (PubMed)

  4. Dog (Canine) Polyclonal TDO2 Primary Antibody for IHC, WB - ABIN2782334 : Blaschke, Mueller, Markovic-Lipkovski, Puch, Miosge, Becker, Mueller, Klein: Expression of cadherin-8 in renal cell carcinoma and fetal kidney. in International journal of cancer. Journal international du cancer 2002 (PubMed)

More Antibodies against Tryptophan 2,3-Dioxygenase Interaction Partners

Human Tryptophan 2,3-Dioxygenase (TDO2) interaction partners

  1. Crystal tryptophan 2,3-dioxygenase structure revealed eight residues playing critical roles in L-tryptophan oxidation.

  2. IL-1beta (show IL1B Antibodies) is suggested to stimulate tryptophan catabolism and production of IL-6 (show IL6 Antibodies) and IL-8 (show IL8 Antibodies) by increasing TDO (show DLX3 Antibodies) expression in endometriosis.

  3. Identification of 12 polymorphisms in the human TDO2 promoter region, 2 of them corresponding to previously unknown single-nucleotide polymorphisms and 3 of them located in putative glucocorticoid-responsive elements.

  4. TDO (show DLX3 Antibodies) is highly expressed in the brains of Alzheimer disease patients.

  5. The data suggest that TDO (show DLX3 Antibodies) uses a ring-opening mechanism during N-formylkynurenine formation, rather than Criegee or dioxetane mechanisms as previously proposed.

  6. subtle differences between the TDO (show DLX3 Antibodies) and IDO (show IDO1 Antibodies) reactions

  7. Polymorphism of tryptophan 2,3 dioxygenase gene is associated with autism.

  8. We found that astrocytes, neurons, and microglia expressed IDO (show IDO1 Antibodies) but only microglia were able to produce detectable amounts of quinolinic acid. However, astrocytes and neurons had the ability to catabolize quinolinic acid.

  9. The tyrosine 42 of recombinant human TDO (show DLX3 Antibodies) is responsible for the cooperative binding of l-Trp (show TBPL1 Antibodies) by participating in the active site of the adjacent subunit.

  10. TDO (show DLX3 Antibodies) mediates antimicrobial and immunoregulatory effects. TDO (show DLX3 Antibodies)-dependent inhibition of T-cell growth might be involved in the immunotolerance observed in vivo during allogeneic liver transplantation.

Mouse (Murine) Tryptophan 2,3-Dioxygenase (TDO2) interaction partners

  1. both TDO and IDO (show IDO1 Antibodies) biosynthesize nicotinamide from D-tryptophan and L-tryptophan in mice

  2. Data indicate that tryptophan 2,3-dioxygenase (Tdo2) may play an important role during mouse decidualization and be regulated by estrogen, progesterone, and cAMP.

  3. These findings demonstrate a direct molecular link between Trp (show TYRP1 Antibodies) metabolism and neurogenesis and anxiety-related behavior under physiological conditions.

  4. Endometrial expression of TDO in epithelial and stromal cells is regulated by HOXA10 (show HOXA10 Antibodies). Expression level of TDO influences infiltration of T-cells into endometrial stroma and thus may influence embryo viability.

  5. These findings indicate that TDO might be required at a late-stage of granule cell development, such as during axonal and dendritic growth, synaptogenesis and its maturation.

  6. No relationship was found between alcohol consumption, Tdo2 activity, and single nucleotide substitution in intron 6 of the Tdo2 gene assoiated with predisposition to alcoholism in humans.

  7. Our findings indicate that TDO and its novel variants may play an important role in not only the liver but also in local areas in developing and adult brain.

Tryptophan 2,3-Dioxygenase (TDO2) Antigen Profile

Protein Summary

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.

Gene names and symbols associated with TDO2

  • tryptophan 2,3-dioxygenase b (tdo2b) antibody
  • tryptophan 2,3-dioxygenase (tdo2) antibody
  • tryptophan 2,3-dioxygenase (TDO2) antibody
  • tryptophan 2,3-dioxygenase (MADE_02822) antibody
  • tryptophan 2,3-dioxygenase (CtCNB1_3657) antibody
  • tryptophan 2,3-dioxygenase a (tdo2a) antibody
  • tryptophan 2,3-dioxygenase (CNC04830) antibody
  • tryptophan 2,3-dioxygenase (tdo) antibody
  • tryptophan 2,3-dioxygenase (Mrub_2119) antibody
  • tryptophan 2,3-dioxygenase (Deipr_2235) antibody
  • tryptophan 2,3-dioxygenase (Acav_1166) antibody
  • tryptophan 2,3-dioxygenase (Mesop_4278) antibody
  • tryptophan 2,3-dioxygenase (Tdo2) antibody
  • tryptophan 2,3-dioxygenase (TDO) antibody
  • AA407491 antibody
  • chky antibody
  • DDBDRAFT_0190495 antibody
  • DDBDRAFT_0231363 antibody
  • DDB_0190495 antibody
  • DDB_0231363 antibody
  • fb62b10 antibody
  • fi30d08 antibody
  • Tdo antibody
  • tdo2 antibody
  • tdo2l antibody
  • TO antibody
  • TPH2 antibody
  • TRPO antibody
  • wu:fb62b10 antibody
  • wu:fi30d08 antibody
  • zgc:63488 antibody
  • zgc:103693 antibody

Protein level used designations for TDO2

TDO-B , TO-B , TRPO-B , tryptamin 2,3-dioxygenase B , tryptophan 2,3-dioxygenase B , tryptophan 2,3-dioxygenase, like , tryptophan oxygenase B , tryptophan pyrrolase B , tryptophanase B , TDO , TO , TRPO , tryptamin 2,3-dioxygenase , tryptophan oxygenase , tryptophan pyrrolase , tryptophanase , tryptophan 2,3-dioxygenase , TDO-A , TO-A , TRPO-A , tryptamin 2,3-dioxygenase A , tryptophan 2,3-dioxygenase A , tryptophan oxygenase A , tryptophan pyrrolase A , tryptophanase A , tdo variant1 , tdo variant2 , tryptophan-2,3-dioxygenase , tryptophan-23-dioxygenase

GENE ID SPECIES
334082 Danio rerio
548450 Xenopus (Silurana) tropicalis
699739 Macaca mulatta
736252 Pan troglodytes
4456236 Ralstonia eutropha H16
4649802 Gramella forsetii KT0803
6776077 Alteromonas macleodii 'Deep ecotype'
8562285 Comamonas testosteroni CNB-2
100008541 Danio rerio
3256592 Cryptococcus neoformans var. neoformans JEC21
8617171 Dictyostelium discoideum AX4
8880228 Meiothermus ruber DSM 1279
10265555 Deinococcus proteolyticus MRP
10306071 Acidovorax avenae subsp. avenae ATCC 19860
10828127 Mesorhizobium opportunistum WSM2075
6999 Homo sapiens
475476 Canis lupus familiaris
56720 Mus musculus
64206 Rattus norvegicus
530397 Bos taurus
100344083 Oryctolagus cuniculus
100727713 Cavia porcellus
100301559 Sus scrofa
422409 Gallus gallus
495495 Xenopus laevis
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