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Tu Translation Elongation Factor, Mitochondrial Proteins (Tufm)

Tufm encodes a protein which participates in protein translation in mitochondria. Additionally we are shipping Tu Translation Elongation Factor, Mitochondrial Antibodies (63) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Tufm 7284 P49411
Tufm 233870 Q8BFR5
Tufm 293481 P85834
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Top Tu Translation Elongation Factor, Mitochondrial Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Acinetobacter baumannii His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Acinetobacter baumannii His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,405.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,135.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,135.00
Details

Tufm Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Tu Translation Elongation Factor, Mitochondrial (Tufm) Interaction Partners

Human Tu Translation Elongation Factor, Mitochondrial (Tufm) interaction partners

  1. TUFM is a novel regulator of epithelial-mesenchymal transition (EMT (show ITK Proteins)); there may be a molecular link between mitochondrial dysfunction and EMT (show ITK Proteins) induction

  2. NLRX1 and TUFM work in concert to reduce cytokine response and augment autophagy.

  3. Increased expression of TUFM is a promising new prognostic indicator for colorectal carcinoma.

  4. By recruiting Atg5 (show ATG5 Proteins)-Atg12 (show ATG12 Proteins) and NLRX1, TUFM serves as a nodal checkpoint of the RIG-I (show DDX58 Proteins)-MAVS (show MAVS Proteins) axis. It acts similarly to NLRX1 by inhibiting RigI (show DDX58 Proteins)-like-receptor-induced IFN-I but promoting autophagy.

  5. Genetic investigation of patients with defective mitochondrial translation led to the discovery of novel mutations in the mitochondrial elongation factor G1 (EFG1 (show GFM1 Proteins)) in one affected baby and in the mitochondrial elongation factor Tu (show EEF1A1 Proteins) (EFTu) in another one

  6. Myoblasts isolated from the MELAS patients show A3243G mutation in tRNALeu(UUR) produces a severe respiratory chain deficiency and this phenotype can be partially suppressed by overexpression of EFTu and EFG2 (show GFM2 Proteins).

  7. Results suggest that the R336Q mutant mt-EFTu variant fails to bind to aminoacylated mitochondrial tRNAs, thus explaining the observed impairment of mitochondrial translation.

Cow (Bovine) Tu Translation Elongation Factor, Mitochondrial (Tufm) interaction partners

  1. Loss of activity is caused by a significant reduction in the ability of EF-Ts (show TSFM Proteins)(mt) R325W to bind EF-Tu(mt), leading to a defect in nucleotide exchange.

  2. Recombinant mitochondrial EF-Tu prevents thermal aggregation of proteins and enhances protein refolding in vitro.

  3. The arginine residue at position 335 of bovine mitochondrial elongation factor Tu (EF-Tu (show EEF1A1 Proteins)) plays an important role in the binding and EF-Tu-mediated delivery of mitochondrial aminoacyl-tRNAs to the A-site of the ribosome.

Mouse (Murine) Tu Translation Elongation Factor, Mitochondrial (Tufm) interaction partners

  1. By recruiting Atg5 (show ATG5 Proteins)-Atg12 (show ATG12 Proteins) and NLRX1, TUFM serves as a nodal checkpoint of the RIG-I (show DDX58 Proteins)-MAVS (show MAVS Proteins) axis. It acts similarly to NLRX1 by inhibiting RigI (show DDX58 Proteins)-like-receptor-induced IFN-I but promoting autophagy.

Tu Translation Elongation Factor, Mitochondrial (Tufm) Protein Profile

Protein Summary

This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.

Gene names and symbols associated with Tufm

  • Tu translation elongation factor, mitochondrial (TUFM)
  • Tu translation elongation factor, mitochondrial (tufm)
  • Tu translation elongation factor, mitochondrial (Tufm)
  • 2300002G02Rik protein
  • C76308 protein
  • C76389 protein
  • COXPD4 protein
  • D250 protein
  • EF-TuMT protein
  • EFTU protein
  • fi06f04 protein
  • P43 protein
  • TUFM protein
  • wu:fi06f04 protein
  • zgc:110766 protein

Protein level used designations for Tufm

Tu translation elongation factor, mitochondrial , elongation factor Tu, mitochondrial-like , elongation factor Tu, mitochondrial , EF-Tu

GENE ID SPECIES
454018 Pan troglodytes
705462 Macaca mulatta
100455214 Pongo abelii
541378 Danio rerio
7284 Homo sapiens
479796 Canis lupus familiaris
281556 Bos taurus
233870 Mus musculus
293481 Rattus norvegicus
430889 Gallus gallus
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