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Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Additionally we are shipping TBCC Antibodies (65) and many more products for this protein.
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Human TBCC Protein expressed in Escherichia coli (E. coli) - ABIN1098366
Gonçalves, Nolasco, Nascimento, Lopez Fanarraga, Zabala, Soares: TBCCD1, a new centrosomal protein, is required for centrosome and Golgi apparatus positioning. in EMBO reports 2010
Show all 2 references for ABIN1098366
a testable model for TBCC N-terminal domain/tubulin (show TUBB Proteins) recognition in which the highly charged N-terminus as well as residues from the three helices and the loops interact with the acidic hypervariable regions of tubulin (show TUBB Proteins) monomers
Microtubule dynamicity was reduced in breast cancer cells overexpressing TBCC. Cell cycle distribution was altered in cells containing larger amounts of TBCC. TBCC had little effect on cell proliferation.
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex\; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
tubulin-folding cofactor C
, tubulin-specific chaperone C
, beta-tubulin cofactor C