anti-Tubulin Folding Cofactor E (TBCE) Antibodies

Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Additionally we are shipping TBCE Proteins (6) and TBCE Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TBCE 70430 Q8CIV8
TBCE 6905 Q15813
TBCE 361255 Q5FVQ9
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Top anti-TBCE Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB TBCE Antibody (Center) western blot analysis in CEM,K562 cell line lysates (35µg/lane).This demonstrates the TBCE antibody detected the TBCE protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB TBCE Antibody (Center) (ABIN653623) western blot analysis in CEM,K562 cell line lysates (35 µg/lane).This demonstrates the TBCE antibody detected the TBCE protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of TBCE expression in transfected 293T cell line by TBCE MaxPab polyclonal antibody.Lane 1: TBCE transfected lysate(57.97 KDa).Lane 2: Non-transfected lysate. TBCE MaxPab polyclonal antibody. Western Blot analysis of TBCE expression in human spleen. 50 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB   0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemistry: PAC2 Antibody (1E8) [NBP2-45438] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) Immunohistochemistry: PAC2 Antibody (1E8) [NBP2-45438] - Analysis of Human Kidney tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using TBCE antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of TBCE transfected lysate using anti-TBCE MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with TBCE purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of TBCE expression in transfected 293T cell line by TBCE MaxPab polyclonal antibody.Lane 1: TBCE transfected lysate(59.30 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 11 to 12 Days
$418.57
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: PAC2 Antibody [NBP2-30576] - Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry: PAC2 Antibody [NBP2-30574] - Immunohistochemical staining of human kidney shows strong luminal membranous positivity in renal tubules. Immunocytochemistry/Immunofluorescence: PAC2 Antibody [NBP2-30574] - Staining of human cell line U-251 MG shows positivity in nucleus. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details

TBCE Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TBCE Antibodies

  1. Human Polyclonal TBCE Primary Antibody for WB - ABIN653623 : Biernacki, Marina, Zhang, Liu, Bruns, Cai, Neuberg, Canning, Alyea, Soiffer, Brusic, Ritz, Wu: Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells. in Cancer research 2010 (PubMed)
    Show all 5 references for 653623

  2. Human Polyclonal TBCE Primary Antibody for EIA, WB - ABIN955104 : Padidela, Kelberman, Press, Al-Khawari, Hindmarsh, Dattani: Mutation in the TBCE gene is associated with hypoparathyroidism-retardation-dysmorphism syndrome featuring pituitary hormone deficiencies and hypoplasia of the anterior pituitary and the corpus callosum. in The Journal of clinical endocrinology and metabolism 2009 (PubMed)
    Show all 3 references for 955104

  3. Human Polyclonal TBCE Primary Antibody for WB - ABIN520724 : Bellouze, Schäfer, Buttigieg, Baillat, Rabouille, Haase: Golgi fragmentation in pmn mice is due to a defective ARF1/TBCE cross-talk that coordinates COPI vesicle formation and tubulin polymerization. in Human molecular genetics 2014 (PubMed)

  4. Human Polyclonal TBCE Primary Antibody for ICC, IF - ABIN4358010 : Sferra, Baillat, Rizza, Barresi, Flex, Tasca, DAmico, Bellacchio, Ciolfi, Caputo, Cecchetti, Torella, Zanni, Diodato, Piermarini, Niceta, Coppola, Tedeschi, Martinelli, Dionisi-Vici, Nigro et al.: TBCE Mutations Cause Early-Onset Progressive Encephalopathy with Distal Spinal Muscular Atrophy. ... in American journal of human genetics 2016 (PubMed)

More Antibodies against TBCE Interaction Partners

Human Tubulin Folding Cofactor E (TBCE) interaction partners

  1. Although loss of function of TBCE has been documented to impact multiple developmental processes, the present findings provide evidence that hypomorphic TBCE mutations primarily drive neurodegeneration

  2. Sanjad-Sakati syndrome molecular pathology has been shown to be due to mutations in the TBCE gene on chromosome 1q42-q43.

  3. the role of the human TBCE and TBCB (show TBCB Antibodies) chaperones in alpha-tubulin (show TUBA4A Antibodies)-beta-tubulin (show TUBB Antibodies) dissociation, was investigated.

  4. tudies confirmed elevated expression of three target antigens RAB38, TBCE, and DUSP12 in CML.

  5. TBCE has a role in membrane trafficking in the Golgi and late endosomal compartments, tubulin (show TUBB Antibodies) assembly, and the development of the parathyroid

  6. Tbce is critical for the maintenance of microtubules in mouse motor axons

  7. The tubulin-specific chaperone E (Tbce) mutation described here suggests that alterations in tubulin (show TUBB Antibodies) assembly lead to retrograde degeneration of motor axons, ultimately resulting in motoneuron cell death.

  8. Reviews recent findings on the molecular mechanisms of the development of the parathyroid glands, with special emphasis on the possible role of tubulin chaperone E (TBCE), implicated in the hypopathyroidism, retardation and dysmorphism (HRD) syndrome.

  9. TBCE, TBCB (show TBCB Antibodies) and alpha-tubulin (show TUBA4A Antibodies) form a ternary complex after heterodimer dissociation. These complexes might serve to escort alpha-tubulin (show TUBA4A Antibodies) towards degradation or recycling, depending on the cell requirements.

  10. Depletion of Op18 (show STMN1 Antibodies) by means of RNA interference increased the susceptibility of tubulin (show TUBB Antibodies) to TBCE or E-like (show TBCEL Antibodies) mediated disruption, while overexpressed Op18 (show STMN1 Antibodies) exerted a tubulin (show TUBB Antibodies)-protective effect.

Mouse (Murine) Tubulin Folding Cofactor E (TBCE) interaction partners

  1. ARF1 (show ARF1 Antibodies)/TBCE-mediated cross-talk that coordinates COPI formation and tubulin (show TUBB Antibodies) polymerization at the Golgi.

  2. We conclude from our study that the mutation of the TBCE gene affects the auditory nerve and the cochlear hair cells simultaneously, leading to progressive hearing loss

  3. Tbce is critical for the maintenance of microtubules in mouse motor axons

TBCE Antigen Profile

Protein Summary

Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex\; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with TBCE

  • tubulin-specific chaperone E (Tbce) antibody
  • tubulin folding cofactor E (TBCE) antibody
  • tubulin folding cofactor E (Tbce) antibody
  • 2610206D02Rik antibody
  • C530005D02Rik antibody
  • HRD antibody
  • KCS antibody
  • KCS1 antibody
  • pac2 antibody
  • pmn antibody

Protein level used designations for TBCE

progressive motor neuropathy , tubulin-folding cofactor E , Kenny-Caffey syndrome , tubulin-specific chaperone E , beta-tubulin cofactor E

GENE ID SPECIES
70430 Mus musculus
6905 Homo sapiens
361255 Rattus norvegicus
505066 Bos taurus
100172438 Pongo abelii
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