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anti-Tubulin Polymerization Promoting Protein (Tppp) Antibodies

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. Additionally we are shipping Tppp Kits (38) and Tppp Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Tppp 11076 O94811
Tppp 72948 Q7TQD2
Tppp 361466  
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Top anti-Tppp Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated EIA, IHC (p), WB AP21274PU-N TPPP Antibody staining of paraffin embedded Human Cerebral Cortex at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. AP21274PU-N TPPP Antibody staining of Human Cerebellum lysate at 0.001 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Mouse Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB TPPP Antibody (Center)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TPPP antibody detected the TPPP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

Tppp Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Top referenced anti-Tppp Antibodies

  1. Chicken Polyclonal Tppp Primary Antibody for WB - ABIN2780164 : Tirián, Hlavanda, Oláh, Horváth, Orosz, Szabó, Kovács, Szabad, Ovádi: TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)

  2. Human Polyclonal Tppp Primary Antibody for EIA, IHC (p) - ABIN499122 : Ovádi, Orosz: An unstructured protein with destructive potential: TPPP/p25 in neurodegeneration. in BioEssays : news and reviews in molecular, cellular and developmental biology 2009 (PubMed)

More Antibodies against Tppp Interaction Partners

Human Tubulin Polymerization Promoting Protein (Tppp) interaction partners

  1. the central folded domain of TPPP/p25 following binding to microtubules can drive s homotypic protein-protein interactions leading to bundled microtubules.

  2. Results reveal a link between p25 (show LCN2 Antibodies) and BACE1 (show BACE Antibodies) in Alzheimer disease (AD) brains and suggest that upregulated Cdk5 (show CDK5 Antibodies) activation by p25 (show LCN2 Antibodies) accelerates AD pathogenesis by enhancing BACE1 (show BACE Antibodies) activity via phosphorylation.

  3. Epigenetic changes in TPPP, in combination with experiences of maltreatment, may confer risk for depression in children.

  4. suggest that the zinc as a specific divalent cation could be involved in the fine-tuning of the physiological TPPP/p25 level counteracting both the enrichment and the lack of this protein leading to distinct central nervous system diseases

  5. results suggest that ROCK regulates beta-catenin (show CTNNB1 Antibodies) stability in cells via preventing TPPP1-mediated inhibition of HDAC6 (show HDAC6 Antibodies) activity, to reduce its acetylation and degradation via phosphorylation by CK1 (show CSNK1A1L Antibodies) and GSK3beta (show GSK3b Antibodies)

  6. GSK3 (show GSK3b Antibodies) promotes the mitochondrial translocation of p53 (show TP53 Antibodies), enabling its interaction with Bcl2 (show BCL2 Antibodies) to allow Bax (show BAX Antibodies) oligomerization and the subsequent release of cytochrome C (show CYCS Antibodies).

  7. dual Rock and Cdk (show CDK4 Antibodies) phosphorylation of Tppp1 inhibits its regulation of the cell cycle to increase cell proliferation

  8. The RhoA (show RHOA Antibodies)-ROCK-LIMK2 (show LIMK2 Antibodies)-TPPP pathway controls metaphase spindle-orientation; TPPP colocalizes with LIMK2 (show LIMK2 Antibodies) at the mitotic spindle.

  9. Although serine-129 phosphorylation of alpha-synuclein (show SNCA Antibodies) facilitates TPPP-mediated alpha-SYN oligomerization, this modification does not seem to play an inevitable role in the early step of alpha-SYN oligomer formation in a cellular model of multiple system atrophy.

  10. The authors conclude that the modest structural changes that p25alpha undergoes can promote weak intermolecular contacts and that polyanions such as heparin play a central role in stabilizing these aggregates.

Mouse (Murine) Tubulin Polymerization Promoting Protein (Tppp) interaction partners

  1. These results support an essential role for TPPP/p25 in oligodendrocyte differentiation likely via rearrangement of the microtubule system during the process elongation prior to the onset of myelination.

  2. LIMK1 phosphorylation of p25 blocks p25 activity, thus promoting microtubule disassembly.

  3. A pathway was discovered by which p25 (show CDK5R1 Antibodies) and cdk5 (show CDK5 Antibodies) increases the amyloidogenic processing of amyloid precursor protein (show APP Antibodies).

Tppp Antigen Profile

Protein Summary

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.

Gene names and symbols associated with Tppp

  • tubulin polymerization promoting protein (TPPP) antibody
  • tubulin polymerization promoting protein (Tppp) antibody
  • tubulin polymerization promoting protein-like (LOC100358311) antibody
  • 2900041A09Rik antibody
  • AI849835 antibody
  • p24 antibody
  • p25 antibody
  • p25alpha antibody
  • RGD1310121 antibody
  • TPPP/p25 antibody
  • TPPP1 antibody

Protein level used designations for Tppp

brain-specific protein p25 alpha , 25 kDa brain-specific protein , brain specific protein p25 alpha , glycogen synthase kinase 3 (GSK3) inhibitor p24 , p25-alpha , tubulin polymerization-promoting protein , tubulin polymerization promoting protein p25 alpha

GENE ID SPECIES
420800 Gallus gallus
11076 Homo sapiens
488072 Canis lupus familiaris
100144410 Sus scrofa
280968 Bos taurus
72948 Mus musculus
361466 Rattus norvegicus
100734397 Cavia porcellus
101110090 Ovis aries
100358311 Oryctolagus cuniculus
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