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Tubulin Polymerization Promoting Protein Proteins (Tppp)

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. Additionally we are shipping Tppp Antibodies (69) and Tppp Kits (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Tppp 11076 O94811
Tppp 72948 Q7TQD2
Rat Tppp Tppp 361466  
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Top Tppp Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,541.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

Tppp Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Tubulin Polymerization Promoting Protein (Tppp) Interaction Partners

Human Tubulin Polymerization Promoting Protein (Tppp) interaction partners

  1. the central folded domain of TPPP/p25 following binding to microtubules can drive s homotypic protein-protein interactions leading to bundled microtubules.

  2. Results reveal a link between p25 (show LCN2 Proteins) and BACE1 (show BACE Proteins) in Alzheimer disease (AD) brains and suggest that upregulated Cdk5 (show CDK5 Proteins) activation by p25 (show LCN2 Proteins) accelerates AD pathogenesis by enhancing BACE1 (show BACE Proteins) activity via phosphorylation.

  3. Epigenetic changes in TPPP, in combination with experiences of maltreatment, may confer risk for depression in children.

  4. suggest that the zinc as a specific divalent cation could be involved in the fine-tuning of the physiological TPPP/p25 level counteracting both the enrichment and the lack of this protein leading to distinct central nervous system diseases

  5. results suggest that ROCK regulates beta-catenin stability in cells via preventing TPPP1-mediated inhibition of HDAC6 activity, to reduce its acetylation and degradation via phosphorylation by CK1 and GSK3beta

  6. GSK3 promotes the mitochondrial translocation of p53 (show TP53 Proteins), enabling its interaction with Bcl2 (show BCL2 Proteins) to allow Bax (show BAX Proteins) oligomerization and the subsequent release of cytochrome C (show CYCS Proteins).

  7. dual Rock and Cdk (show CDK4 Proteins) phosphorylation of Tppp1 inhibits its regulation of the cell cycle to increase cell proliferation

  8. The RhoA (show RHOA Proteins)-ROCK-LIMK2 (show LIMK2 Proteins)-TPPP pathway controls metaphase spindle-orientation; TPPP colocalizes with LIMK2 (show LIMK2 Proteins) at the mitotic spindle.

  9. Although serine-129 phosphorylation of alpha-synuclein facilitates TPPP-mediated alpha-SYN oligomerization, this modification does not seem to play an inevitable role in the early step of alpha-SYN oligomer formation in a cellular model of multiple system atrophy.

  10. The authors conclude that the modest structural changes that p25alpha undergoes can promote weak intermolecular contacts and that polyanions such as heparin play a central role in stabilizing these aggregates.

Mouse (Murine) Tubulin Polymerization Promoting Protein (Tppp) interaction partners

  1. These results support an essential role for TPPP/p25 in oligodendrocyte differentiation likely via rearrangement of the microtubule system during the process elongation prior to the onset of myelination.

  2. LIMK1 phosphorylation of p25 blocks p25 activity, thus promoting microtubule disassembly.

  3. A pathway was discovered by which p25 (show CDK5R1 Proteins) and cdk5 (show CDK5 Proteins) increases the amyloidogenic processing of amyloid precursor protein (show APP Proteins).

Tppp Protein Profile

Protein Summary

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.

Gene names and symbols associated with Tppp

  • tubulin polymerization promoting protein (TPPP)
  • tubulin polymerization promoting protein (Tppp)
  • tubulin polymerization promoting protein-like (LOC100358311)
  • 2900041A09Rik protein
  • AI849835 protein
  • p24 protein
  • p25 protein
  • p25alpha protein
  • RGD1310121 protein
  • TPPP/p25 protein
  • TPPP1 protein

Protein level used designations for Tppp

brain-specific protein p25 alpha , 25 kDa brain-specific protein , brain specific protein p25 alpha , glycogen synthase kinase 3 (GSK3) inhibitor p24 , p25-alpha , tubulin polymerization-promoting protein , tubulin polymerization promoting protein p25 alpha

GENE ID SPECIES
420800 Gallus gallus
11076 Homo sapiens
488072 Canis lupus familiaris
100144410 Sus scrofa
280968 Bos taurus
72948 Mus musculus
361466 Rattus norvegicus
100734397 Cavia porcellus
101110090 Ovis aries
100358311 Oryctolagus cuniculus
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